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Lysine-specific histone demethylase 1A
Summary
- UniProt ID
- O60341
- Gene Symbol
-
- KDM1A
- AOF2
- KDM1
- KIAA0601
- LSD1
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- O60341
- PubChem
- O60341
- The Human Metabolome Database
- HMDBP08273
- The O-GlcNAc Database
- O60341
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Alternative splicing
- Chromatin regulator
- Chromosome
- Coiled coil
- Developmental protein
- Direct protein sequencing
- Disease variant
- FAD
- Isopeptide bond
- Nucleus
- Oxidoreductase
- Phosphoprotein
- Reference proteome
- Repressor
- Transcription regulation
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| chromatin |
| nucleus |
| protein-containing complex |
| chromosome, telomeric region |
| nucleoplasm |
| transcription regulator complex |
| DNA repair complex |
Sequence
MLSGKKAAAAAAAAAAAATGTEAGPGTAGGSENGSEVAAQPAGLSGPAEVGPGAVGERTPRKKEPPRASPPGGLAEPPGSAGPQAGPTVVPGSATPMETGIAETPEGRRTSRRKRAKVEYREMDESLANLSEDEYYSEEERNAKAEKEKKLPPPPPQAPPEEENESEPEEPSGVEGAAFQSRLPHDRMTSQEAACFPDIISGPQQTQKVFLFIRNRTLQLWLDNPKIQLTFEATLQQLEAPYNSDTVLVHRVHSYLERHGLINFGIYKRIKPLPTKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLGAMVVTGLGGNPMAVVSKQVNMELAKIKQKCPLYEANGQAVPKEKDEMVEQEFNRLLEATSYLSHQLDFNVLNNKPVSLGQALEVVIQLQEKHVKDEQIEHWKKIVKTQEELKELLNKMVNLKEKIKELHQQYKEASEVKPPRDITAEFLVKSKHRDLTALCKEYDELAETQGKLEEKLQELEANPPSDVYLSSRDRQILDWHFANLEFANATPLSTLSLKHWDQDDDFEFTGSHLTVRNGYSCVPVALAEGLDIKLNTAVRQVRYTASGCEVIAVNTRSTSQTFIYKCDAVLCTLPLGVLKQQPPAVQFVPPLPEWKTSAVQRMGFGNLNKVVLCFDRVFWDPSVNLFGHVGSTTASRGELFLFWNLYKAPILLALVAGEAAGIMENISDDVIVGRCLAILKGIFGSSAVPQPKETVVSRWRADPWARGSYSYVAAGSSGNDYDLMAQPITPGPSIPGAPQPIPRLFFAGEHTIRNYPATVHGALLSGLREAGRIADQFLGAMYTLPRQATPGVPAQQSPSM
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 35 |
|
|||
| 335 |
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 | Homo sapiens |
| Estrogen-dependent gene expression | Homo sapiens |
| Factors involved in megakaryocyte development and platelet production | Homo sapiens |
| HDACs deacetylate histones | Homo sapiens |
| HDMs demethylate histones | Homo sapiens |
| LXRs regulate gene expression linked to cholesterol transport and efflux | Homo sapiens |
| Potential therapeutics for SARS | Homo sapiens |
| Regulation of PTEN gene transcription | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
