Factors involved in megakaryocyte development and platelet production

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
RAD51BRAD51B:RAD51CRAD51CRAD51B:RAD51C:Single-stranded DNASingle-stranded DNADual-specific AKAPsDual-specific AKAPs:PKA tetramerPKA tetramerMitofusinsMitofusin complexSIN3Ap53:MYB:SIN3AMYBTP53 TetramerIFNB1 geneIRF1:Promotors of IFN alpha, IFN betaIFNA genesIRF1Type-I IFN genesIFNA/BIRF2:promoters of INF alpha, INF betaIRF2CBX5HP1alpha:Histone H3 methylated at K9Histone H3 methylated at lysine-9ATPADPI(3,4,5,6)P4I(1,3,4,5,6)P5I(1,3,4)P3I(1,3,4,5)P4I(1,3,4,6)P4CPLRRC16A:F-actin capping proteinLRRC16ACAPZBCAPZAf-actinF-actin capping protein:f-actinTPNHTPNO2H2O2BHC complexBHC complex:REST:REST DNA binding sitesREST:REST DNA binding sitesGATA proteinsZFPM proteins:GATA proteinsZFPM1, ZFPM2Histone H3 mono or di-methylated at K9Histone H3 mono- or unmethylated at K9p-Y813-JAK2SH2B family:p-Y813-JAK2SH2B familyGTPADPAMPGDPSmall Maf family membersNF-E2NFE2Promotor region of beta-globinNF-E2:Promoter region of beta-globinGlobin genesHBG2HBDHBG1HBE1HBBC-terminal EH domain containing proteinsC-terminal EH domain containing proteins:Rabenosyn-5ZFYVE20Rabenosyn-5:VPS-45VPS45RAB5ADOCK-GEFsDOCK-GEFs:RAC1, CDC42RAC1, CDC42CABLESCDK5:CABLES:ABLABL1CDK5WEE1CDK2:CABLES1:WEE1CDK2CABLES1
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
Displaying entries 1 - 10 of 50 in total
UniProt ID Protein Name Gene Symbol Pathway Viewer
O15315 DNA repair protein RAD51 homolog 2
  • RAD51B
  • RAD51L1
  • REC2
view
O15525 Transcription factor MafG
  • MAFG
view
O43502 DNA repair protein RAD51 homolog 3
  • RAD51C
  • RAD51L2
view
O60341 Lysine-specific histone demethylase 1A
  • AOF2
  • KDM1
  • KDM1A
  • KIAA0601
  • LSD1
view
O60675 Transcription factor MafK
  • MAFK
view
P00519 Tyrosine-protein kinase ABL1
  • ABL
  • ABL1
  • JTK7
view
P01563 Interferon alpha-2
  • IFNA2
  • IFNA2A
  • IFNA2B
  • IFNA2C
view
P01570 Interferon alpha-14
  • IFNA14
view
P01574 Interferon beta
  • IFB
  • IFNB
  • IFNB1
view
P04637 Cellular tumor antigen p53
  • P53
  • TP53
view
a simple tooltip

About Release Notes Help Feedback

Click here to visit the beta site.


International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


Logo License Policies Site Map

Contact: support@glycosmos.org

This work is licensed under Creative Commons Attribution 4.0 International


GlyCosmos Portal v4.1.1

Last updated: February 17, 2025