GlyCosmos Portal

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GO Term	Evidence Code	PMID
protein binding	IPI	16530705 20224550 21130043 22939624 23878260 27991863 35384245
vascular endothelial growth factor receptor activity	IBA IDA IMP	11532940 19779139 23878260 9012504
transmembrane receptor protein tyrosine kinase activity	IMP	7898938
protein phosphatase binding	IPI	20826270
growth factor binding	IPI	9435229

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

protein kinase activity [inference]

protein tyrosine kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity

vascular endothelial growth factor receptor activity

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity

vascular endothelial growth factor receptor activity

phosphotransferase activity, alcohol group as acceptor [inference]

protein kinase activity [inference]

protein tyrosine kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity

vascular endothelial growth factor receptor activity

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity

vascular endothelial growth factor receptor activity

catalytic activity, acting on a protein [inference]

protein kinase activity [inference]

protein tyrosine kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity

vascular endothelial growth factor receptor activity

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity

vascular endothelial growth factor receptor activity

binding [inference]

protein binding

growth factor binding

enzyme binding [inference]

phosphatase binding [inference]

protein phosphatase binding

identical protein binding [inference]

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity

vascular endothelial growth factor receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Vascular endothelial growth factor receptor 2

Functional Category

I: Lipid transport and metabolism
K: Transcription
T: Signal transduction mechanisms

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Gene Ontology
ATP binding
angiogenesis
cell migration
endothelial cell differentiation
growth factor binding
metal ion binding
nucleotide binding
positive regulation of angiogenesis
positive regulation of cell migration
regulation of MAPK cascade

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InterPro
Tyrosine-protein kinase, active site
Tyrosine-protein kinase, catalytic domain
Tyrosine-protein kinase, receptor class III, conserved site
VEGFR-2, transmembrane domain

Disease

Disease Ontology

Displaying **all 8** entries
DO ID	Disease Name	Source
DOID:0050580	hereditary lymphedema	Alliance of Genome Resources
DOID:0070210	hereditary lymphedema IA	Alliance of Genome Resources
DOID:1475	lymphangioma	Alliance of Genome Resources
DOID:162	cancer	Alliance of Genome Resources
DOID:305	carcinoma	Alliance of Genome Resources
DOID:3963	thyroid gland carcinoma	Alliance of Genome Resources
DOID:418	systemic scleroderma	Alliance of Genome Resources
DOID:585	nephrolithiasis	Alliance of Genome Resources

Ortholog

Displaying entries **11 - 20** of 78 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Oryctolagus cuniculus	100008829			RABIT14962
Equus caballus	100066773			HORSE08319
Ornithorhynchus anatinus	100087557			ORNAN28365
Taeniopygia guttata	100218470			TAEGU04179
Oryzias latipes	100335137			ORYLA01286
Callithrix jacchus	100388404			CALJA26937
Pongo abelii	100462098	9601_0:00165f		PONAB29766
Ailuropoda melanoleuca	100478767			AILME03986
Xenopus tropicalis	100493801		Xenbase:XB-GENE-483183
Sus scrofa	100518179			PIGXX19063

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements