GlyCosmos Portal

Submissions

C-type lectin domain containing 16A

Summary

Gene Symbol

CLEC16A

Aliases

Gop-1

Organism

Homo sapiens (human)

External Links

NCBI Gene

23274

HGNC

29013

KEGG Gene ID

hsa:23274

PubChem

23274

Alliance of Genome Resources

HGNC:29013

Annotation

Keyword

Alternative splicing
Autophagy
Diabetes mellitus
Endosome
Lysosome
Membrane
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
Q2KHT3	C-type lectin domain family 16 member A

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
endosome to lysosome transport	IBA
positive regulation of TORC1 signaling	IMP	28223137
negative regulation of autophagosome maturation	IMP	28223137
cellular response to starvation	IMP	28223137
autophagy	IEA

GO Hierarchy

biological process

metabolic process [inference]

catabolic process [inference]

cellular catabolic process [inference]

autophagy

cellular metabolic process [inference]

cellular catabolic process [inference]

autophagy

cellular process [inference]

cell communication [inference]

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation

vesicle-mediated transport [inference]

cellular metabolic process [inference]

cellular catabolic process [inference]

autophagy

cellular localization [inference]

intracellular transport [inference]

vacuolar transport [inference]

lysosomal transport [inference]

endosome to lysosome transport

endosomal transport

cellular response to stimulus [inference]

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation

cellular response to stress [inference]

cellular response to starvation

process utilizing autophagic mechanism [inference]

autophagy

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

cellular response to starvation

response to starvation [inference]

cellular response to starvation

response to external stimulus [inference]

response to extracellular stimulus [inference]

response to nutrient levels [inference]

cellular response to nutrient levels [inference]

cellular response to starvation

response to starvation [inference]

cellular response to starvation

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation

cellular response to external stimulus [inference]

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation

cellular response to stimulus [inference]

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation

cellular response to stress [inference]

cellular response to starvation

localization [inference]

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

intracellular transport [inference]

vacuolar transport [inference]

lysosomal transport [inference]

endosome to lysosome transport

endosomal transport

establishment of localization in cell [inference]

intracellular transport [inference]

vacuolar transport [inference]

lysosomal transport [inference]

endosome to lysosome transport

endosomal transport

cellular localization [inference]

intracellular transport [inference]

vacuolar transport [inference]

lysosomal transport [inference]

endosome to lysosome transport

endosomal transport

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

negative regulation of metabolic process [inference]

negative regulation of catabolic process [inference]

negative regulation of cellular catabolic process [inference]

negative regulation of autophagy [inference]

negative regulation of macroautophagy [inference]

negative regulation of autophagosome maturation

negative regulation of cellular metabolic process [inference]

negative regulation of cellular catabolic process [inference]

negative regulation of autophagy [inference]

negative regulation of macroautophagy [inference]

negative regulation of autophagosome maturation

regulation of catabolic process [inference]

negative regulation of catabolic process [inference]

negative regulation of cellular catabolic process [inference]

negative regulation of autophagy [inference]

negative regulation of macroautophagy [inference]

negative regulation of autophagosome maturation

regulation of cellular catabolic process [inference]

regulation of autophagy [inference]

negative regulation of autophagy [inference]

negative regulation of macroautophagy [inference]

negative regulation of autophagosome maturation

regulation of macroautophagy [inference]

negative regulation of macroautophagy [inference]

negative regulation of autophagosome maturation

regulation of autophagosome maturation

negative regulation of autophagosome maturation

negative regulation of cellular catabolic process [inference]

negative regulation of autophagy [inference]

negative regulation of macroautophagy [inference]

negative regulation of autophagosome maturation

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular catabolic process [inference]

negative regulation of autophagy [inference]

negative regulation of macroautophagy [inference]

negative regulation of autophagosome maturation

regulation of cellular catabolic process [inference]

regulation of autophagy [inference]

negative regulation of autophagy [inference]

negative regulation of macroautophagy [inference]

negative regulation of autophagosome maturation

regulation of macroautophagy [inference]

negative regulation of macroautophagy [inference]

negative regulation of autophagosome maturation

regulation of autophagosome maturation

negative regulation of autophagosome maturation

negative regulation of cellular catabolic process [inference]

negative regulation of autophagy [inference]

negative regulation of macroautophagy [inference]

negative regulation of autophagosome maturation

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of TOR signaling [inference]

positive regulation of TORC1 signaling

regulation of intracellular signal transduction [inference]

regulation of TOR signaling [inference]

positive regulation of TOR signaling [inference]

positive regulation of TORC1 signaling

regulation of TORC1 signaling [inference]

positive regulation of TORC1 signaling

positive regulation of intracellular signal transduction [inference]

positive regulation of TOR signaling [inference]

positive regulation of TORC1 signaling

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of TOR signaling [inference]

positive regulation of TORC1 signaling

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of TOR signaling [inference]

positive regulation of TORC1 signaling

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of TOR signaling [inference]

positive regulation of TORC1 signaling

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of TOR signaling [inference]

positive regulation of TORC1 signaling

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of catabolic process [inference]

negative regulation of cellular catabolic process [inference]

negative regulation of autophagy [inference]

negative regulation of macroautophagy [inference]

negative regulation of autophagosome maturation

negative regulation of cellular metabolic process [inference]

negative regulation of cellular catabolic process [inference]

negative regulation of autophagy [inference]

negative regulation of macroautophagy [inference]

negative regulation of autophagosome maturation

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular catabolic process [inference]

negative regulation of autophagy [inference]

negative regulation of macroautophagy [inference]

negative regulation of autophagosome maturation

negative regulation of cellular component organization [inference]

negative regulation of protein-containing complex disassembly [inference]

negative regulation of autophagosome maturation

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of TOR signaling [inference]

positive regulation of TORC1 signaling

regulation of intracellular signal transduction [inference]

regulation of TOR signaling [inference]

positive regulation of TOR signaling [inference]

positive regulation of TORC1 signaling

regulation of TORC1 signaling [inference]

positive regulation of TORC1 signaling

positive regulation of intracellular signal transduction [inference]

positive regulation of TOR signaling [inference]

positive regulation of TORC1 signaling

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of TOR signaling [inference]

positive regulation of TORC1 signaling

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of TOR signaling [inference]

positive regulation of TORC1 signaling

regulation of intracellular signal transduction [inference]

regulation of TOR signaling [inference]

positive regulation of TOR signaling [inference]

positive regulation of TORC1 signaling

regulation of TORC1 signaling [inference]

positive regulation of TORC1 signaling

positive regulation of intracellular signal transduction [inference]

positive regulation of TOR signaling [inference]

positive regulation of TORC1 signaling

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of TOR signaling [inference]

positive regulation of TORC1 signaling

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular catabolic process [inference]

negative regulation of autophagy [inference]

negative regulation of macroautophagy [inference]

negative regulation of autophagosome maturation

regulation of cellular catabolic process [inference]

regulation of autophagy [inference]

negative regulation of autophagy [inference]

negative regulation of macroautophagy [inference]

negative regulation of autophagosome maturation

regulation of macroautophagy [inference]

negative regulation of macroautophagy [inference]

negative regulation of autophagosome maturation

regulation of autophagosome maturation

negative regulation of autophagosome maturation

negative regulation of cellular catabolic process [inference]

negative regulation of autophagy [inference]

negative regulation of macroautophagy [inference]

negative regulation of autophagosome maturation

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of TOR signaling [inference]

positive regulation of TORC1 signaling

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular catabolic process [inference]

negative regulation of autophagy [inference]

negative regulation of macroautophagy [inference]

negative regulation of autophagosome maturation

negative regulation of cellular component organization [inference]

negative regulation of protein-containing complex disassembly [inference]

negative regulation of autophagosome maturation

regulation of cellular component organization [inference]

regulation of organelle organization [inference]

regulation of autophagosome maturation

negative regulation of autophagosome maturation

regulation of protein-containing complex disassembly [inference]

negative regulation of protein-containing complex disassembly [inference]

negative regulation of autophagosome maturation

regulation of autophagosome maturation

negative regulation of autophagosome maturation

negative regulation of cellular component organization [inference]

negative regulation of protein-containing complex disassembly [inference]

negative regulation of autophagosome maturation

Displaying **all 5** entries
GO Term	Evidence Code	PMID
vesicle	IDA	28223137
cytosol	IDA	28223137
endolysosome membrane	IBA
Golgi apparatus	IDA	28223137
late endosome	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytosol

membrane [inference]

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endosome membrane [inference]

endolysosome membrane

bounding membrane of organelle [inference]

vacuolar membrane [inference]

lytic vacuole membrane [inference]

lysosomal membrane [inference]

endolysosome membrane

endosome membrane [inference]

endolysosome membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

late endosome

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

late endosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

late endosome

Displaying 1 entry
GO Term	Evidence Code	PMID
molecular_function	ND

GO Hierarchy

molecular function

Gene Ontology information from NCBI Gene and UniProt.

Human Protein Atlas

ENSG00000038532

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

Data available from v23.0.proteinatlas.org. Image credit: Human Protein Atlas

KEGG BRITE Database

Orthology

K19513

Name

protein CLEC16A

References

24949970

Disease

Disease Ontology

Displaying entries **1 - 10** of **102** in total

1

2

3

4

5

…

Next ›

Last »
DO ID	Disease Name	Source
DOID:0050589	inflammatory bowel disease	DisGeNET DisGeNET
DOID:0060025	immunoglobulin alpha deficiency	DisGeNET DisGeNET
DOID:0060192	Crohn's colitis	DisGeNET
DOID:0060643	primary sclerosing cholangitis	DisGeNET
DOID:0080348	Alzheimer's disease 1	DisGeNET
DOID:0110035	Alzheimer's disease 2	DisGeNET
DOID:0110037	Alzheimer's disease 5	DisGeNET
DOID:0110038	Alzheimer's disease 6	DisGeNET
DOID:0110039	Alzheimer's disease 7	DisGeNET
DOID:0110041	Alzheimer's disease 8	DisGeNET

PubChem Disease

KEGG Diseases

Type 1 diabetes mellitus

Gene-Disease-Co-Occurrences-in-Literature (PubChem)

Ortholog

Displaying entries **1 - 10** of 75 in total

1

2

3

4

5

…

Next ›

Last »
Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Caenorhabditis elegans	175721	WB:WBGene00001660
Drosophila melanogaster	41992	FB:FBgn0038427
Callorhinchus milii	103186066		CALMI33760
Danio rerio	393184	ZFIN:ZDB-GENE-040426-951
Electrophorus electricus	113572843		ELEEL12055
Oreochromis niloticus	100711144		ORENI55678
Xenopus laevis	108701522	Xenbase:XB-GENE-17334295
Xenopus laevis	108703106	Xenbase:XB-GENE-6489231
Xenopus tropicalis	100488730	Xenbase:XB-GENE-1018324
Chrysemys picta bellii	101934831		CHRPI19444

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

KEGG BRITE Database

PubChem Disease

International Collaboration

Acknowledgements