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nei like 3 (E. coli)

Summary

Gene Symbol

Neil3

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

234258

PubChem

234258

Alliance of Genome Resources

MGI:2384588

Annotation

Keyword

3D-structure
Alternative splicing
Chromosome
DNA repair
DNA-binding
Glycosidase
Lyase
Multifunctional enzyme
Nucleus
Phosphoprotein
Reference proteome
Repeat
Zinc-finger

Proteins

Displaying 1 entry
UniProt	Protein Name
Q8K203	DNA glycosylase FPG2 DNA glycosylase/AP lyase Neil3 Endonuclease VIII-like 3 Nei-like protein 3

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
interstrand cross-link repair	ISS
base-excision repair	IBA IDA ISO	20185759
single strand break repair	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

cellular response to stimulus [inference]

cellular response to stress [inference]

DNA damage response [inference]

DNA repair [inference]

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

DNA damage response [inference]

DNA repair [inference]

cellular response to stimulus [inference]

cellular response to stress [inference]

DNA damage response [inference]

DNA repair [inference]

Displaying **all 3** entries
GO Term	Evidence Code	PMID
nucleoplasm	ISO TAS
nucleus	IBA IDA ISO	16428305
chromosome	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

nucleoplasm

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

chromosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular non-membrane-bounded organelle [inference]

chromosome

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
zinc ion binding	IEA
DNA N-glycosylase activity	IBA IDA ISO TAS	20185759
single-stranded DNA binding	IDA ISO	20185759
bubble DNA binding	IDA	20185759
double-stranded DNA binding	IDA	20185759

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on glycosyl bonds [inference]

hydrolase activity, hydrolyzing N-glycosyl compounds [inference]

DNA N-glycosylase activity

lyase activity [inference]

carbon-oxygen lyase activity [inference]

class I DNA-(apurinic or apyrimidinic site) endonuclease activity

catalytic activity, acting on a nucleic acid [inference]

catalytic activity, acting on DNA [inference]

DNA-(apurinic or apyrimidinic site) endonuclease activity

class I DNA-(apurinic or apyrimidinic site) endonuclease activity

DNA N-glycosylase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

zinc ion binding

protein-containing complex binding [inference]

MCM complex binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

DNA binding [inference]

DNA secondary structure binding [inference]

bubble DNA binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

Zinc finger, RanBP2-type

Functional Category

G: Carbohydrate transport and metabolism
L: Replication, recombination and repair
O: Posttranslational modification, protein turnover, chaperones

Displaying entries **11 - 13** of 13 in total

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Gene Ontology
lyase activity
metal ion binding
zinc ion binding

Displaying **all 9** entries
InterPro
DNA glycosylase/AP lyase, H2TH DNA-binding
DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site
Formamidopyrimidine-DNA glycosylase, catalytic domain
MutM-like, N-terminal
Small ribosomal subunit protein uS13-like, H2TH
Zinc finger, DNA glycosylase/AP lyase-type
Zinc finger, GRF-type
Zinc finger, RanBP2-type superfamily
Zinc finger, RanBP2-type

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:684	hepatocellular carcinoma	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of **107** in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	55247		HGNC:24573	HUMAN78221
Rattus norvegicus	290729	10116_1:004979	RGD:1310562	RATNO11893
Pan troglodytes	471359			PANTR34859
Canis lupus familiaris	475639			CANLF04806
Danio rerio	492463		ZFIN:ZDB-GENE-041114-18	DANRE07885
Bos taurus	515343			BOVIN21889
Xenopus tropicalis	549955		Xenbase:XB-GENE-1001611
Macaca mulatta	699618			MACMU37337
Monodelphis domestica	100017570			MONDO26309
Equus caballus	100060702			HORSE25059

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Last updated: December 9, 2024