GlyCosmos Portal

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
intracellular membrane-bounded organelle	IDA
vacuolar proton-transporting V-type ATPase, V0 domain	IEA
proton-transporting V-type ATPase complex		33065002
transmembrane transporter complex	IEA
plasma membrane	IBA IDA

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

proton-transporting two-sector ATPase complex [inference]

proton-transporting V-type ATPase complex

vacuolar proton-transporting V-type ATPase complex

proton-transporting two-sector ATPase complex, proton-transporting domain [inference]

proton-transporting V-type ATPase, V0 domain [inference]

vacuolar proton-transporting V-type ATPase, V0 domain

transmembrane transporter complex

catalytic complex [inference]

ATPase complex [inference]

proton-transporting two-sector ATPase complex [inference]

proton-transporting V-type ATPase complex

vacuolar proton-transporting V-type ATPase complex

transporter complex [inference]

transmembrane transporter complex

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endosome membrane

endocytic vesicle membrane [inference]

phagocytic vesicle membrane

bounding membrane of organelle [inference]

Golgi membrane

vacuolar membrane [inference]

lytic vacuole membrane [inference]

lysosomal membrane

endosome membrane

endocytic vesicle membrane [inference]

phagocytic vesicle membrane

cell junction [inference]

anchoring junction [inference]

cell-substrate junction [inference]

focal adhesion

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule [inference]

acrosomal vesicle

intracellular membrane-bounded organelle

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule [inference]

acrosomal vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule [inference]

acrosomal vesicle

perinuclear region of cytoplasm

Displaying **all 3** entries
GO Term	Evidence Code	PMID
ATPase binding	IBA
proton-transporting ATPase activity, rotational mechanism	IEA
protein binding	IPI	16415858

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic cation transmembrane transporter activity [inference]

proton transmembrane transporter activity [inference]

proton-transporting ATPase activity, rotational mechanism

ATPase-coupled monoatomic cation transmembrane transporter activity [inference]

proton-transporting ATPase activity, rotational mechanism

active monoatomic ion transmembrane transporter activity [inference]

ATPase-coupled monoatomic cation transmembrane transporter activity [inference]

proton-transporting ATPase activity, rotational mechanism

inorganic molecular entity transmembrane transporter activity [inference]

inorganic cation transmembrane transporter activity [inference]

proton transmembrane transporter activity [inference]

proton-transporting ATPase activity, rotational mechanism

active transmembrane transporter activity [inference]

primary active transmembrane transporter activity [inference]

ATPase-coupled transmembrane transporter activity [inference]

ATPase-coupled monoatomic cation transmembrane transporter activity [inference]

proton-transporting ATPase activity, rotational mechanism

ATPase-coupled ion transmembrane transporter activity [inference]

ATPase activity, coupled to transmembrane movement of ions, rotational mechanism [inference]

proton-transporting ATPase activity, rotational mechanism

active monoatomic ion transmembrane transporter activity [inference]

ATPase-coupled monoatomic cation transmembrane transporter activity [inference]

proton-transporting ATPase activity, rotational mechanism

binding [inference]

protein binding

enzyme binding [inference]

ATPase binding

ATP-dependent activity [inference]

ATPase-coupled transmembrane transporter activity [inference]

ATPase-coupled monoatomic cation transmembrane transporter activity [inference]

proton-transporting ATPase activity, rotational mechanism

ATPase-coupled ion transmembrane transporter activity [inference]

ATPase activity, coupled to transmembrane movement of ions, rotational mechanism [inference]

proton-transporting ATPase activity, rotational mechanism

Gene Ontology information from NCBI Gene and UniProt.

Human Protein Atlas

ENSG00000185344

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

Data available from v23.0.proteinatlas.org. Image credit: Human Protein Atlas

KEGG BRITE Database

Orthology

K02154

Name

V-type H+-transporting ATPase subunit a

References

Disease

Disease Ontology

Displaying entries **51 - 60** of **121** in total

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DO ID	Disease Name	Source
DOID:0111136	congenital generalized lipodystrophy type 2	DisGeNET
DOID:0111137	congenital generalized lipodystrophy type 3	DisGeNET
DOID:0111138	congenital generalized lipodystrophy type 4	DisGeNET
DOID:0111266	geroderma osteodysplasticum	DisGeNET
DOID:0112171	wrinkly skin syndrome	Alliance of Genome Resources
DOID:10461	dentin caries	DisGeNET
DOID:1059	intellectual disability	DisGeNET
DOID:10763	hypertension	DisGeNET
DOID:10825	essential hypertension	DisGeNET
DOID:10907	microcephaly	DisGeNET

The Human Phenotype Ontology

Displaying entries **111 - 114** of **114** in total

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HPO ID	HPO Term
HP:0011995	Atrial septal dilatation
HP:0012368	Flat face
HP:0100874	Thick hair
HP:0200141	Small, conical teeth

Displaying **all 4** entries
Disease ID	Disease Name
OMIM:219200	autosomal recessive cutis laxa type 2A
ORPHA:357074	autosomal recessive cutis laxa type 2, classic type
OMIM:278250	wrinkly skin syndrome
ORPHA:2834	wrinkly skin syndrome

PubChem Disease

GHR Health Conditions

Cutis laxa

MedGen Diseases

OMIM Phenotypes

KEGG Diseases

Cutis laxa

Gene-Disease-Co-Occurrences-in-Literature (PubChem)

Ortholog

Displaying entries **1 - 10** of **106** in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Caenorhabditis elegans	174743	WB:WBGene00006915
Caenorhabditis elegans	176257	WB:WBGene00006768
Caenorhabditis elegans	177626	WB:WBGene00006914
Caenorhabditis elegans	178219	WB:WBGene00006916
Drosophila melanogaster	34587	FB:FBgn0032373
Drosophila melanogaster	42214	FB:FBgn0038613
Drosophila melanogaster	246543	FB:FBgn0028669
Callorhinchus milii	103188002		CALMI38026
Latimeria chalumnae	102351124		LATCH18385
Danio rerio	561117	ZFIN:ZDB-GENE-060526-4	DANRE36906

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

KEGG BRITE Database

PubChem Disease

International Collaboration

Acknowledgements