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protein phosphatase 1 regulatory subunit 15A

Summary

Gene Symbol

PPP1R15A

Organism

Homo sapiens (human)

External Links

NCBI Gene

23645

PubChem

23645

Alliance of Genome Resources

HGNC:14375

Annotation

Keyword

3D-structure
Alternative splicing
Apoptosis
Endoplasmic reticulum
Mitochondrion outer membrane
Phosphoprotein
Reference proteome
Repeat
Stress response
Translation regulation
Ubl conjugation

Proteins

Displaying 1 entry
UniProt	Protein Name
O75807	Growth arrest and DNA damage-inducible protein GADD34 Myeloid differentiation primary response protein MyD116 homolog

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 17 in total

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GO Term	Evidence Code	PMID
positive regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	TAS	22934019
positive regulation of phosphoprotein phosphatase activity
negative regulation of protein dephosphorylation
positive regulation of translational initiation in response to stress

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation [inference]

regulation of translational initiation by eIF2 alpha dephosphorylation

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

dephosphorylation [inference]

protein dephosphorylation [inference]

regulation of translational initiation by eIF2 alpha dephosphorylation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation [inference]

regulation of translational initiation by eIF2 alpha dephosphorylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation [inference]

regulation of translational initiation by eIF2 alpha dephosphorylation

macromolecule modification [inference]

protein modification process [inference]

protein dephosphorylation [inference]

regulation of translational initiation by eIF2 alpha dephosphorylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation [inference]

regulation of translational initiation by eIF2 alpha dephosphorylation

cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

intrinsic apoptotic signaling pathway [inference]

intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress

apoptotic signaling pathway [inference]

intrinsic apoptotic signaling pathway [inference]

intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress

cell death [inference]

programmed cell death [inference]

apoptotic process

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

dephosphorylation [inference]

protein dephosphorylation [inference]

regulation of translational initiation by eIF2 alpha dephosphorylation

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to endoplasmic reticulum

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to DNA damage stimulus

response to endoplasmic reticulum stress

intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress

cellular component organization or biogenesis [inference]

cellular component organization [inference]

regulation of cellular component size [inference]

regulation of translational initiation by eIF2 alpha dephosphorylation

regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation [inference]

positive regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

cellular response to DNA damage stimulus

response to endoplasmic reticulum stress

intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to DNA damage stimulus

response to endoplasmic reticulum stress

intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to endoplasmic reticulum

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to endoplasmic reticulum

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation [inference]

positive regulation of translational initiation [inference]

positive regulation of translational initiation in response to stress

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

post-transcriptional regulation of gene expression [inference]

regulation of translation [inference]

regulation of translational initiation

regulation of translational initiation in response to stress

regulation of translational initiation by eIF2 alpha dephosphorylation

positive regulation of translational initiation [inference]

positive regulation of translational initiation in response to stress

regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation [inference]

positive regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation

regulation of translation in response to stress [inference]

regulation of translational initiation in response to stress

regulation of translational initiation by eIF2 alpha dephosphorylation

positive regulation of translation [inference]

positive regulation of translational initiation [inference]

positive regulation of translational initiation in response to stress

positive regulation of gene expression [inference]

positive regulation of translation [inference]

positive regulation of translational initiation [inference]

positive regulation of translational initiation in response to stress

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation [inference]

positive regulation of translational initiation [inference]

positive regulation of translational initiation in response to stress

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation [inference]

positive regulation of translational initiation [inference]

positive regulation of translational initiation in response to stress

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein dephosphorylation

negative regulation of phosphoprotein phosphatase activity

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of dephosphorylation [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity

negative regulation of protein dephosphorylation

negative regulation of phosphoprotein phosphatase activity

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein dephosphorylation

negative regulation of phosphoprotein phosphatase activity

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation [inference]

positive regulation of translational initiation [inference]

positive regulation of translational initiation in response to stress

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation [inference]

positive regulation of translational initiation [inference]

positive regulation of translational initiation in response to stress

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein dephosphorylation [inference]

positive regulation of translation [inference]

positive regulation of translational initiation [inference]

positive regulation of translational initiation in response to stress

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of dephosphorylation [inference]

positive regulation of phosphatase activity [inference]

positive regulation of phosphoprotein phosphatase activity

positive regulation of protein dephosphorylation [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation [inference]

positive regulation of translational initiation [inference]

positive regulation of translational initiation in response to stress

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of amide metabolic process [inference]

positive regulation of translation [inference]

positive regulation of translational initiation [inference]

positive regulation of translational initiation in response to stress

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein dephosphorylation [inference]

positive regulation of translation [inference]

positive regulation of translational initiation [inference]

positive regulation of translational initiation in response to stress

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of dephosphorylation [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity

negative regulation of protein dephosphorylation

negative regulation of phosphoprotein phosphatase activity

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of dephosphorylation [inference]

positive regulation of phosphatase activity [inference]

positive regulation of phosphoprotein phosphatase activity

positive regulation of protein dephosphorylation [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation [inference]

positive regulation of translational initiation [inference]

positive regulation of translational initiation in response to stress

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

post-transcriptional regulation of gene expression [inference]

regulation of translation [inference]

regulation of translational initiation

regulation of translational initiation in response to stress

regulation of translational initiation by eIF2 alpha dephosphorylation

positive regulation of translational initiation [inference]

positive regulation of translational initiation in response to stress

regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation [inference]

positive regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation

regulation of translation in response to stress [inference]

regulation of translational initiation in response to stress

regulation of translational initiation by eIF2 alpha dephosphorylation

positive regulation of translation [inference]

positive regulation of translational initiation [inference]

positive regulation of translational initiation in response to stress

positive regulation of gene expression [inference]

positive regulation of translation [inference]

positive regulation of translational initiation [inference]

positive regulation of translational initiation in response to stress

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation [inference]

positive regulation of translational initiation [inference]

positive regulation of translational initiation in response to stress

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation [inference]

positive regulation of translational initiation [inference]

positive regulation of translational initiation in response to stress

regulation of phosphorus metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of dephosphorylation [inference]

positive regulation of phosphatase activity [inference]

positive regulation of phosphoprotein phosphatase activity

positive regulation of protein dephosphorylation [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of dephosphorylation [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity

negative regulation of protein dephosphorylation

negative regulation of phosphoprotein phosphatase activity

regulation of phosphate metabolic process [inference]

regulation of dephosphorylation [inference]

regulation of phosphatase activity [inference]

positive regulation of phosphatase activity [inference]

positive regulation of phosphoprotein phosphatase activity

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity

regulation of phosphoprotein phosphatase activity [inference]

regulation of protein dephosphorylation [inference]

positive regulation of protein dephosphorylation [inference]

negative regulation of protein dephosphorylation

negative regulation of phosphoprotein phosphatase activity

regulation of phosphoprotein phosphatase activity [inference]

regulation of peptidyl-serine dephosphorylation [inference]

positive regulation of peptidyl-serine dephosphorylation

regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation [inference]

positive regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation

negative regulation of dephosphorylation [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity

negative regulation of protein dephosphorylation

negative regulation of phosphoprotein phosphatase activity

positive regulation of dephosphorylation [inference]

positive regulation of phosphatase activity [inference]

positive regulation of phosphoprotein phosphatase activity

positive regulation of protein dephosphorylation [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of dephosphorylation [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity

negative regulation of protein dephosphorylation

negative regulation of phosphoprotein phosphatase activity

positive regulation of phosphate metabolic process [inference]

positive regulation of dephosphorylation [inference]

positive regulation of phosphatase activity [inference]

positive regulation of phosphoprotein phosphatase activity

positive regulation of protein dephosphorylation [inference]

regulation of nitrogen compound metabolic process [inference]

regulation of amide metabolic process [inference]

regulation of translation [inference]

regulation of translational initiation

regulation of translational initiation in response to stress

regulation of translational initiation by eIF2 alpha dephosphorylation

positive regulation of translational initiation [inference]

positive regulation of translational initiation in response to stress

regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation [inference]

positive regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation

regulation of translation in response to stress [inference]

regulation of translational initiation in response to stress

regulation of translational initiation by eIF2 alpha dephosphorylation

positive regulation of translation [inference]

positive regulation of translational initiation [inference]

positive regulation of translational initiation in response to stress

positive regulation of amide metabolic process [inference]

positive regulation of translation [inference]

positive regulation of translational initiation [inference]

positive regulation of translational initiation in response to stress

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein dephosphorylation

negative regulation of phosphoprotein phosphatase activity

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of amide metabolic process [inference]

positive regulation of translation [inference]

positive regulation of translational initiation [inference]

positive regulation of translational initiation in response to stress

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein dephosphorylation [inference]

positive regulation of translation [inference]

positive regulation of translational initiation [inference]

positive regulation of translational initiation in response to stress

regulation of protein metabolic process [inference]

regulation of translation [inference]

regulation of translational initiation

regulation of translational initiation in response to stress

regulation of translational initiation by eIF2 alpha dephosphorylation

positive regulation of translational initiation [inference]

positive regulation of translational initiation in response to stress

regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation [inference]

positive regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation

regulation of translation in response to stress [inference]

regulation of translational initiation in response to stress

regulation of translational initiation by eIF2 alpha dephosphorylation

positive regulation of translation [inference]

positive regulation of translational initiation [inference]

positive regulation of translational initiation in response to stress

regulation of protein modification process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein dephosphorylation

negative regulation of phosphoprotein phosphatase activity

positive regulation of protein modification process [inference]

positive regulation of protein dephosphorylation [inference]

regulation of protein dephosphorylation [inference]

positive regulation of protein dephosphorylation [inference]

negative regulation of protein dephosphorylation

negative regulation of phosphoprotein phosphatase activity

regulation of phosphoprotein phosphatase activity [inference]

regulation of peptidyl-serine dephosphorylation [inference]

positive regulation of peptidyl-serine dephosphorylation

regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation [inference]

positive regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein dephosphorylation [inference]

positive regulation of translation [inference]

positive regulation of translational initiation [inference]

positive regulation of translational initiation in response to stress

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein dephosphorylation

negative regulation of phosphoprotein phosphatase activity

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

post-transcriptional regulation of gene expression [inference]

regulation of translation [inference]

regulation of translational initiation

regulation of translational initiation in response to stress

regulation of translational initiation by eIF2 alpha dephosphorylation

positive regulation of translational initiation [inference]

positive regulation of translational initiation in response to stress

regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation [inference]

positive regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation

regulation of translation in response to stress [inference]

regulation of translational initiation in response to stress

regulation of translational initiation by eIF2 alpha dephosphorylation

positive regulation of translation [inference]

positive regulation of translational initiation [inference]

positive regulation of translational initiation in response to stress

positive regulation of gene expression [inference]

positive regulation of translation [inference]

positive regulation of translational initiation [inference]

positive regulation of translational initiation in response to stress

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation [inference]

positive regulation of translational initiation [inference]

positive regulation of translational initiation in response to stress

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation [inference]

positive regulation of translational initiation [inference]

positive regulation of translational initiation in response to stress

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein dephosphorylation [inference]

positive regulation of translation [inference]

positive regulation of translational initiation [inference]

positive regulation of translational initiation in response to stress

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein dephosphorylation

negative regulation of phosphoprotein phosphatase activity

regulation of protein metabolic process [inference]

regulation of translation [inference]

regulation of translational initiation

regulation of translational initiation in response to stress

regulation of translational initiation by eIF2 alpha dephosphorylation

positive regulation of translational initiation [inference]

positive regulation of translational initiation in response to stress

regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation [inference]

positive regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation

regulation of translation in response to stress [inference]

regulation of translational initiation in response to stress

regulation of translational initiation by eIF2 alpha dephosphorylation

positive regulation of translation [inference]

positive regulation of translational initiation [inference]

positive regulation of translational initiation in response to stress

regulation of protein modification process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein dephosphorylation

negative regulation of phosphoprotein phosphatase activity

positive regulation of protein modification process [inference]

positive regulation of protein dephosphorylation [inference]

regulation of protein dephosphorylation [inference]

positive regulation of protein dephosphorylation [inference]

negative regulation of protein dephosphorylation

negative regulation of phosphoprotein phosphatase activity

regulation of phosphoprotein phosphatase activity [inference]

regulation of peptidyl-serine dephosphorylation [inference]

positive regulation of peptidyl-serine dephosphorylation

regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation [inference]

positive regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein dephosphorylation [inference]

positive regulation of translation [inference]

positive regulation of translational initiation [inference]

positive regulation of translational initiation in response to stress

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein dephosphorylation

negative regulation of phosphoprotein phosphatase activity

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of translation [inference]

regulation of translational initiation

regulation of translational initiation in response to stress

regulation of translational initiation by eIF2 alpha dephosphorylation

positive regulation of translational initiation [inference]

positive regulation of translational initiation in response to stress

regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation [inference]

positive regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation

regulation of translation in response to stress [inference]

regulation of translational initiation in response to stress

regulation of translational initiation by eIF2 alpha dephosphorylation

positive regulation of translation [inference]

positive regulation of translational initiation [inference]

positive regulation of translational initiation in response to stress

regulation of protein modification process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein dephosphorylation

negative regulation of phosphoprotein phosphatase activity

positive regulation of protein modification process [inference]

positive regulation of protein dephosphorylation [inference]

regulation of protein dephosphorylation [inference]

positive regulation of protein dephosphorylation [inference]

negative regulation of protein dephosphorylation

negative regulation of phosphoprotein phosphatase activity

regulation of phosphoprotein phosphatase activity [inference]

regulation of peptidyl-serine dephosphorylation [inference]

positive regulation of peptidyl-serine dephosphorylation

regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation [inference]

positive regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein dephosphorylation [inference]

positive regulation of translation [inference]

positive regulation of translational initiation [inference]

positive regulation of translational initiation in response to stress

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein dephosphorylation

negative regulation of phosphoprotein phosphatase activity

regulation of signaling [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

regulation of PERK-mediated unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation [inference]

positive regulation of translational initiation [inference]

positive regulation of translational initiation in response to stress

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation [inference]

positive regulation of translational initiation [inference]

positive regulation of translational initiation in response to stress

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein dephosphorylation [inference]

positive regulation of translation [inference]

positive regulation of translational initiation [inference]

positive regulation of translational initiation in response to stress

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of dephosphorylation [inference]

positive regulation of phosphatase activity [inference]

positive regulation of phosphoprotein phosphatase activity

positive regulation of protein dephosphorylation [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation [inference]

positive regulation of translational initiation [inference]

positive regulation of translational initiation in response to stress

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of amide metabolic process [inference]

positive regulation of translation [inference]

positive regulation of translational initiation [inference]

positive regulation of translational initiation in response to stress

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein dephosphorylation [inference]

positive regulation of translation [inference]

positive regulation of translational initiation [inference]

positive regulation of translational initiation in response to stress

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of dephosphorylation [inference]

positive regulation of phosphatase activity [inference]

positive regulation of phosphoprotein phosphatase activity

positive regulation of protein dephosphorylation [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation [inference]

positive regulation of translational initiation [inference]

positive regulation of translational initiation in response to stress

positive regulation of cellular component organization [inference]

positive regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein dephosphorylation

negative regulation of phosphoprotein phosphatase activity

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of dephosphorylation [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity

negative regulation of protein dephosphorylation

negative regulation of phosphoprotein phosphatase activity

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein dephosphorylation

negative regulation of phosphoprotein phosphatase activity

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of dephosphorylation [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity

negative regulation of protein dephosphorylation

negative regulation of phosphoprotein phosphatase activity

negative regulation of response to endoplasmic reticulum stress [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

negative regulation of response to endoplasmic reticulum stress [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

regulation of PERK-mediated unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

negative regulation of response to endoplasmic reticulum stress [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

regulation of response to stress [inference]

regulation of cellular response to stress [inference]

regulation of response to endoplasmic reticulum stress [inference]

regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

regulation of PERK-mediated unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

negative regulation of response to endoplasmic reticulum stress [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

regulation of cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

intrinsic apoptotic signaling pathway [inference]

intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress

apoptotic signaling pathway [inference]

intrinsic apoptotic signaling pathway [inference]

intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress

regulation of cell communication [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

regulation of PERK-mediated unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of dephosphorylation [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity

negative regulation of protein dephosphorylation

negative regulation of phosphoprotein phosphatase activity

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of dephosphorylation [inference]

positive regulation of phosphatase activity [inference]

positive regulation of phosphoprotein phosphatase activity

positive regulation of protein dephosphorylation [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation [inference]

positive regulation of translational initiation [inference]

positive regulation of translational initiation in response to stress

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

post-transcriptional regulation of gene expression [inference]

regulation of translation [inference]

regulation of translational initiation

regulation of translational initiation in response to stress

regulation of translational initiation by eIF2 alpha dephosphorylation

positive regulation of translational initiation [inference]

positive regulation of translational initiation in response to stress

regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation [inference]

positive regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation

regulation of translation in response to stress [inference]

regulation of translational initiation in response to stress

regulation of translational initiation by eIF2 alpha dephosphorylation

positive regulation of translation [inference]

positive regulation of translational initiation [inference]

positive regulation of translational initiation in response to stress

positive regulation of gene expression [inference]

positive regulation of translation [inference]

positive regulation of translational initiation [inference]

positive regulation of translational initiation in response to stress

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation [inference]

positive regulation of translational initiation [inference]

positive regulation of translational initiation in response to stress

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation [inference]

positive regulation of translational initiation [inference]

positive regulation of translational initiation in response to stress

regulation of phosphorus metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of dephosphorylation [inference]

positive regulation of phosphatase activity [inference]

positive regulation of phosphoprotein phosphatase activity

positive regulation of protein dephosphorylation [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of dephosphorylation [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity

negative regulation of protein dephosphorylation

negative regulation of phosphoprotein phosphatase activity

regulation of phosphate metabolic process [inference]

regulation of dephosphorylation [inference]

regulation of phosphatase activity [inference]

positive regulation of phosphatase activity [inference]

positive regulation of phosphoprotein phosphatase activity

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity

regulation of phosphoprotein phosphatase activity [inference]

regulation of protein dephosphorylation [inference]

positive regulation of protein dephosphorylation [inference]

negative regulation of protein dephosphorylation

negative regulation of phosphoprotein phosphatase activity

regulation of phosphoprotein phosphatase activity [inference]

regulation of peptidyl-serine dephosphorylation [inference]

positive regulation of peptidyl-serine dephosphorylation

regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation [inference]

positive regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation

negative regulation of dephosphorylation [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity

negative regulation of protein dephosphorylation

negative regulation of phosphoprotein phosphatase activity

positive regulation of dephosphorylation [inference]

positive regulation of phosphatase activity [inference]

positive regulation of phosphoprotein phosphatase activity

positive regulation of protein dephosphorylation [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of dephosphorylation [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity

negative regulation of protein dephosphorylation

negative regulation of phosphoprotein phosphatase activity

positive regulation of phosphate metabolic process [inference]

positive regulation of dephosphorylation [inference]

positive regulation of phosphatase activity [inference]

positive regulation of phosphoprotein phosphatase activity

positive regulation of protein dephosphorylation [inference]

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of dephosphorylation [inference]

positive regulation of phosphatase activity [inference]

positive regulation of phosphoprotein phosphatase activity

positive regulation of protein dephosphorylation [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation [inference]

positive regulation of translational initiation [inference]

positive regulation of translational initiation in response to stress

positive regulation of cellular component organization [inference]

positive regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of dephosphorylation [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity

negative regulation of protein dephosphorylation

negative regulation of phosphoprotein phosphatase activity

negative regulation of response to endoplasmic reticulum stress [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

regulation of cellular component organization [inference]

positive regulation of cellular component organization [inference]

positive regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation

regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation [inference]

positive regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation

regulation of cell cycle

regulation of cellular response to stress [inference]

regulation of response to endoplasmic reticulum stress [inference]

regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

regulation of PERK-mediated unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

negative regulation of response to endoplasmic reticulum stress [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of PERK-mediated unfolded protein response

regulation of biological quality [inference]

regulation of anatomical structure size [inference]

regulation of cellular component size [inference]

regulation of translational initiation by eIF2 alpha dephosphorylation

regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation [inference]

positive regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation

regulation of molecular function [inference]

negative regulation of molecular function [inference]

negative regulation of catalytic activity [inference]

negative regulation of hydrolase activity [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity

positive regulation of molecular function [inference]

positive regulation of catalytic activity [inference]

positive regulation of hydrolase activity [inference]

positive regulation of phosphatase activity [inference]

positive regulation of phosphoprotein phosphatase activity

regulation of catalytic activity [inference]

positive regulation of catalytic activity [inference]

positive regulation of hydrolase activity [inference]

positive regulation of phosphatase activity [inference]

positive regulation of phosphoprotein phosphatase activity

negative regulation of catalytic activity [inference]

negative regulation of hydrolase activity [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity

regulation of hydrolase activity [inference]

regulation of phosphatase activity [inference]

positive regulation of phosphatase activity [inference]

positive regulation of phosphoprotein phosphatase activity

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity

regulation of phosphoprotein phosphatase activity [inference]

positive regulation of hydrolase activity [inference]

positive regulation of phosphatase activity [inference]

positive regulation of phosphoprotein phosphatase activity

negative regulation of hydrolase activity [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
protein phosphatase type 1 complex	IBA IDA	11564868 12556489
membrane	IDA	21518769
Golgi apparatus	IDA	21518769
endoplasmic reticulum membrane	NAS	21518769
mitochondrial outer membrane	IEA

GO Hierarchy

cellular component

protein-containing complex [inference]

catalytic complex [inference]

phosphatase complex [inference]

protein serine/threonine phosphatase complex [inference]

protein phosphatase type 1 complex

cellular anatomical entity [inference]

membrane

outer membrane [inference]

organelle outer membrane [inference]

mitochondrial outer membrane

organelle membrane [inference]

endoplasmic reticulum membrane

mitochondrial membrane [inference]

mitochondrial outer membrane

bounding membrane of organelle [inference]

organelle outer membrane [inference]

mitochondrial outer membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Displaying **all 5** entries
GO Term	Evidence Code	PMID
protein binding	IPI	11564868 15231748 21988832 26095357 29109149
protein phosphatase 1 binding	IDA IPI	11564868 12556489 21518769
protein kinase binding	IPI	11517336
protein phosphatase activator activity
protein phosphatase regulator activity	IBA IDA	12556489

GO Hierarchy

molecular function

binding [inference]

protein binding

enzyme binding [inference]

kinase binding [inference]

protein kinase binding

phosphatase binding [inference]

protein phosphatase binding [inference]

protein phosphatase 1 binding

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme activator activity [inference]

phosphatase activator activity [inference]

protein phosphatase activator activity

phosphatase regulator activity [inference]

phosphatase activator activity [inference]

protein phosphatase activator activity

protein phosphatase regulator activity

protein phosphatase activator activity

molecular function activator activity [inference]

enzyme activator activity [inference]

phosphatase activator activity [inference]

protein phosphatase activator activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

uncharacterized protein

Functional Category

G: Carbohydrate transport and metabolism
J: Translation, ribosomal structure and biogenesis
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
negative regulation of phosphate metabolic process
negative regulation of protein modification process
response to endoplasmic reticulum stress

Displaying 1 entry
InterPro
Protein phosphatase 1, regulatory subunit 15A/B, C-terminal

Disease

Disease Ontology

Displaying **all 3** entries
DO ID	Disease Name	Source
DOID:10241	thalassemia	Alliance of Genome Resources
DOID:224	transient cerebral ischemia	Alliance of Genome Resources
DOID:2316	brain ischemia	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 43 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Mus musculus	17872		MGI:1927072	MOUSE54899
Drosophila melanogaster	37820		FB:FBgn0034948
Rattus norvegicus	171071		RGD:621526	RATNO17270
Xenopus tropicalis	394604		Xenbase:XB-GENE-5742862
Pan troglodytes	456191	9598_0:004dde		PANTR18862
Bos taurus	514688			BOVIN11476
Macaca mulatta	718350			MACMU18158
Danio rerio	797943		ZFIN:ZDB-GENE-030131-4408
Equus caballus	100051382			HORSE01031
Pongo abelii	100449481	9601_0:004aff		PONAB15805

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements