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Protein phosphatase 1 regulatory subunit 15A

Summary

UniProt ID

O75807

Gene Symbol

PPP1R15A
GADD34

Organism

Homo sapiens (human)

External Links

GlyGen: O75807
PubChem: O75807
The Human Metabolome Database: HMDBP14465

Annotation

Keyword

3D-structure
Alternative splicing
Apoptosis
Endoplasmic reticulum
Mitochondrion outer membrane
Phosphoprotein
Reference proteome
Repeat
Stress response
Translation regulation
Ubl conjugation

Gene Ontology (GO)

Displaying entries **1 - 10** of 14 in total

1

2

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GO Term
negative regulation of phosphoprotein phosphatase activity
positive regulation of phosphoprotein phosphatase activity
negative regulation of PERK-mediated unfolded protein response
positive regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation
protein localization to endoplasmic reticulum
negative regulation of protein dephosphorylation
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
positive regulation of translational initiation in response to stress
regulation of translational initiation by eIF2 alpha dephosphorylation
positive regulation of peptidyl-serine dephosphorylation

Displaying **all 9** entries
GO Term
endoplasmic reticulum
endoplasmic reticulum membrane
Golgi apparatus
cytosol
cytoplasm
mitochondrion
membrane
protein phosphatase type 1 complex
mitochondrial outer membrane

Displaying **all 4** entries
GO Term
protein phosphatase 1 binding
protein kinase binding
protein phosphatase activator activity
protein phosphatase regulator activity

Annotation information from UniProt.

Sequence

MAPGQAPHQATPWRDAHPFFLLSPVMGLLSRAWSRLRGLGPLEPWLVEAVKGAALVEAGLEGEARTPLAIPHTPWGRRPEEEAEDSGGPGEDRETLGLKTSSSLPEAWGLLDDDDGMYGEREATSVPRGQGSQFADGQRAPLSPSLLIRTLQGSDKNPGEEKAEEEGVAEEEGVNKFSYPPSHRECCPAVEEEDDEEAVKKEAHRTSTSALSPGSKPSTWVSCPGEEENQATEDKRTERSKGARKTSVSPRSSGSDPRSWEYRSGEASEEKEEKAHKETGKGEAAPGPQSSAPAQRPQLKSWWCQPSDEEEGEVKALGAAEKDGEAECPPCIPPPSAFLKAWVYWPGEDTEEEEDEEEDEDSDSGSDEEEGEAEASSSTPATGVFLKSWVYQPGEDTEEEEDEDSDTGSAEDEREAETSASTPPASAFLKAWVYRPGEDTEEEEDEDVDSEDKEDDSEAALGEAESDPHPSHPDQRAHFRGWGYRPGKETEEEEAAEDWGEAEPCPFRVAIYVPGEKPPPPWAPPRLPLRLQRRLKRPETPTHDPDPETPLKARKVRFSEKVTVHFLAVWAGPAQAARQGPWEQLARDRSRFARRITQAQEELSPCLTPAARARAWARLRNPPLAPIPALTQTLPSSSVPSSPVQTTPLSQAVATPSRSSAAAAAALDLSGRRG

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites