Downregulation of TGF-beta receptor signaling

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
SMAD7TGFB1: p-TGFBR: I-SMAD7TGFB1:TGFBR2:p-TGFBR1STRAPTGFB1:p-TGFBR:STRAPTGFB1: p-TGFBR: STRAP: SMAD7TGFB1: TGFBR2: p-TGFBR1: BAMBI: SMAD7BAMBISARATGFB1:p-TGFBR:I-SMAD7:GADD34:PP1:SARAGADD34:PP1H2OPiTGFB1:TGFBR2:TGFBR1SMAD7SMAD7:SMURF2SMURF2SMAD7:SMURF2SMURF1SMAD7:SMURF1SMAD7:SMURF1:XPO1XPO1SMAD7:SMURF1XPO1NEDD4LSMAD7:NEDD4LSMAD7:NEDD4LTGFB1:TGFBR2:p-TGFBR1:SMAD7:SMURF/NEDD4LSMAD7:SMURF/NEDD4LSMURF/NEDD4LUbTGFB1:TGFBR2:Ub-p-TGFBR1:Ub-SMAD7UCHL5/USP15TGFB1:TGFBR2:Ub-p-TGFBR1:Ub-SMAD7:UCHL5/USP15TGFB1:TGFBR2:p-TGFBR1:Ub-SMAD7SMAD2SMAD2:SMURF2SMURF2Ub-SMAD2STUB1SMAD3:STUB1SMAD3STAG1p-2S-SMAD2/3:PMEPA1p-2S-SMAD2,3SMAD2,3SMAD2/3:PMEPA1STAG1p-2S-SMAD2/3:MTMR4MTMR4Ub-SMAD3
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025