Submissions
GlyTouCan
Glycan Structure Repository
GlyComb
Glycoconjugate Repository
GlycoPOST
Glycomics MS raw data Repository
UniCarb-DR
Glycomics MS Repository for glycan annotations from GlycoWorkbench
Resources Genes Glycoproteins Lectins Glycolipids Glycans Pathways Diseases Organisms
All Resources
Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Other Information
Release Statistics Download
Tools
SugarDrawer GlycanBuilder Glycan Converters GlycoMaple GlycomeAtlas LM-GlycomeAtlas GALAXY MCAW GlycoSim GRable
Search Tools
Cross Search Glycan Search Publication Search Programmatic Access
Standards Ontologies Notations
TGF-beta receptor type-2

Summary
UniProt ID
P37173
Gene Symbol
  • TGFBR2
Organism
Homo sapiens (human)
External Links
GlycoProtDB
GPDB0011669
GlyConnect
GlyGen
P37173
PubChem
P37173
The Human Metabolome Database
HMDBP01237
RaftProt
P37173
Annotation
Keyword
  • 3D-structure
  • ATP-binding
  • Alternative splicing
  • Aortic aneurysm
  • Apoptosis
  • Cell membrane
  • Craniosynostosis
  • Differentiation
  • Direct protein sequencing
  • Disease variant
  • Disulfide bond
  • Glycoprotein
  • Growth regulation
  • Hereditary nonpolyposis colorectal cancer
  • Magnesium
  • Manganese
  • Metal-binding
  • Phosphoprotein
  • Receptor
  • Reference proteome
  • Secreted
  • Serine/threonine-protein kinase
  • Signal
  • Transmembrane helix
Gene Ontology (GO)
Annotation information from UniProt.
Sequence
MGRGLLRGLWPLHIVLWTRIASTIPPHVQKSVNNDMIVTDNNGAVKFPQLCKFCDVRFSTCDNQKSCMSNCSITSICEKPQEVCVAVWRKNDENITLETVCHDPKLPYHDFILEDAASPKCIMKEKKKPGETFFMCSCSSDECNDNIIFSEEYNTSNPDLLLVIFQVTGISLLPPLGVAISVIIIFYCYRVNRQQKLSSTWETGKTRKLMEFSEHCAIILEDDRSDISSTCANNINHNTELLPIELDTLVGKGRFAEVYKAKLKQNTSEQFETVAVKIFPYEEYASWKTEKDIFSDINLKHENILQFLTAEERKTELGKQYWLITAFHAKGNLQEYLTRHVISWEDLRKLGSSLARGIAHLHSDHTPCGRPKMPIVHRDLKSSNILVKNDLTCCLCDFGLSLRLDPTLSVDDLANSGQVGTARYMAPEVLESRMNLENVESFKQTDVYSMALVLWEMTSRCNAVGEVKDYEPPFGSKVREHPCVESMKDNVLRDRGRPEIPSFWLNHQGIQMVCETLTECWDHDPEARLTAQCVAERFSELEHLDRLSGRSCSEEKIPEDGSLNTTK
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 7 entries
Position Description PubMed ID GlyTouCan ID Source
31
39
70 N-linked (GlcNAc...) asparagine
94 N-linked (GlcNAc...) asparagine
154 N-linked (GlcNAc...) asparagine
266
564
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 9 entries
Pathway Name Organism
Downregulation of TGF-beta receptor signaling Homo sapiens
SMAD2/3 Phosphorylation Motif Mutants in Cancer Homo sapiens
TGF-beta receptor signaling activates SMADs Homo sapiens
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) Homo sapiens
TGFBR1 KD Mutants in Cancer Homo sapiens
TGFBR1 LBD Mutants in Cancer Homo sapiens
TGFBR2 Kinase Domain Mutants in Cancer Homo sapiens
TGFBR2 MSI Frameshift Mutants in Cancer Homo sapiens
UCH proteinases Homo sapiens
About Release Notes Help Feedback

Click here to visit the beta site.

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

Logo License Policies Site Map

Contact: support@glycosmos.org

This work is licensed under Creative Commons Attribution 4.0 International

GlyCosmos Portal v4.0.0

Last updated: August 19, 2024