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alpha 1,4-galactosyltransferase

Summary

Gene Symbol

A4galt

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

239559

KEGG Gene ID

mmu:239559

PubChem

239559

Alliance of Genome Resources

MGI:3512453

Annotation

Keyword

Glycoprotein
Glycosyltransferase
Golgi apparatus
Lipid biosynthesis
Reference proteome
Signal-anchor
Transmembrane helix

Proteins

Displaying **all 4** entries
UniProt	Protein Name
Q3UF00	Alpha-1,4-N-acetylglucosaminyltransferase Alpha-1,4-galactosyltransferase Globotriaosylceramide synthase UDP-galactose:beta-D-galactosyl-beta1-R 4-alpha-D-galactosyltransferase
Q0R0H6	Alpha-1,4-N-acetylglucosaminyltransferase Alpha-1,4-galactosyltransferase Globotriaosylceramide synthase UDP-galactose:beta-D-galactosyl-beta1-R 4-alpha-D-galactosyltransferase
Q67BJ4	Alpha-1,4-N-acetylglucosaminyltransferase Alpha-1,4-galactosyltransferase Alpha4Gal-T1 Globotriaosylceramide synthase UDP-galactose:beta-D-galactosyl-beta1-R 4-alpha-D-galactosyltransferase
Q3TRS1	Alpha-1,4-N-acetylglucosaminyltransferase Alpha-1,4-galactosyltransferase Globotriaosylceramide synthase UDP-galactose:beta-D-galactosyl-beta1-R 4-alpha-D-galactosyltransferase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
plasma membrane organization	ISO
protein O-linked glycosylation	IBA
lipid metabolic process	IEA
globoside biosynthetic process	IDA IMP	16476743 22875802

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

globoside metabolic process [inference]

globoside biosynthetic process

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

carbohydrate derivative biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

cellular metabolic process [inference]

cellular biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

globoside metabolic process [inference]

globoside biosynthetic process

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

sphingolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

globoside metabolic process [inference]

globoside biosynthetic process

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

primary metabolic process [inference]

lipid metabolic process

lipid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

globoside metabolic process [inference]

globoside biosynthetic process

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

sphingolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

globoside metabolic process [inference]

globoside biosynthetic process

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

globoside metabolic process [inference]

globoside biosynthetic process

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein O-linked glycosylation

organic substance metabolic process [inference]

lipid metabolic process

lipid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

globoside metabolic process [inference]

globoside biosynthetic process

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

sphingolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

globoside metabolic process [inference]

globoside biosynthetic process

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

globoside metabolic process [inference]

globoside biosynthetic process

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein O-linked glycosylation

carbohydrate derivative metabolic process [inference]

carbohydrate derivative biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

globoside metabolic process [inference]

globoside biosynthetic process

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

globoside metabolic process [inference]

globoside biosynthetic process

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

carbohydrate derivative biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

globoside metabolic process [inference]

globoside biosynthetic process

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

sphingolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

globoside metabolic process [inference]

globoside biosynthetic process

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

cellular component organization or biogenesis [inference]

cellular component organization [inference]

membrane organization [inference]

plasma membrane organization

Displaying **all 3** entries
GO Term	Evidence Code	PMID
membrane	ISO
Golgi apparatus	IEA
Golgi membrane

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

organelle membrane [inference]

bounding membrane of organelle [inference]

Golgi membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

Displaying entry **6 - 6** of 6 in total

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GO Term	Evidence Code	PMID
lactosylceramide 4-alpha-galactosyltransferase activity	IDA IMP	16476743 22875802

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity

glycosyltransferase activity

UDP-glycosyltransferase activity [inference]

acetylglucosaminyltransferase activity

UDP-galactosyltransferase activity [inference]

lactosylceramide 4-alpha-galactosyltransferase activity

hexosyltransferase activity [inference]

acetylglucosaminyltransferase activity

galactosyltransferase activity

UDP-galactosyltransferase activity [inference]

lactosylceramide 4-alpha-galactosyltransferase activity

binding [inference]

toxic substance binding

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K01988

Name

lactosylceramide 4-alpha-galactosyltransferase [EC:2.4.1.228]

References

10748143

Reactions

Displaying **all 3** entries
KEGG Reaction	Enzyme	Acceptor	Product
R11375	2.4.1.228	G58896AZ	G12460DL
R05960	2.4.1.228	G84224TW	G00059MO
R11376	2.4.1.228	G00061MO	G33020YH

Rhea

RHEA:11924

a β-D-Gal-(1→4)-β-D-Glc-(1↔1)-Cer(d18:1(4E)) + UDP-α-D-galactose

H⁺ + a globoside Gb3Cer (d18:1(4E)) + UDP

Enzyme

2.4.1.228

PMID

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP000275
Gene Name: alpha 1,4-galactosyltransferase

Ortholog

Displaying entries **1 - 10** of 62 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	33512	FB:FBgn0031491
Drosophila melanogaster	43124	FB:FBgn0039378
Latimeria chalumnae	102364135		LATCH08731
Latimeria chalumnae	102367121		LATCH00394
Xenopus tropicalis	100495236	Xenbase:XB-GENE-493407
Chrysemys picta bellii	101950887		CHRPI35643
Crocodylus porosus	109316363		CROPO04590
Meleagris gallopavo	100550373		MELGA00770
Serinus canaria	103819578		SERCA15051
Ornithorhynchus anatinus	100090950		ORNAN05726

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

KEGG BRITE Database

LIPID MAPS Gene / Proteome Database

International Collaboration

Acknowledgements