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alpha 1,4-galactosyltransferase

Summary

Gene Symbol

A4galt

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

239559

KEGG Gene ID

mmu:239559

PubChem

239559

Alliance of Genome Resources

MGI:3512453

Annotation

Keyword

Glycoprotein
Glycosyltransferase
Golgi apparatus
Lipid biosynthesis
Reference proteome
Signal-anchor
Transmembrane helix

Proteins

Displaying **all 4** entries
UniProt	Protein Name
Q3UF00	Alpha-1,4-N-acetylglucosaminyltransferase Alpha-1,4-galactosyltransferase Globotriaosylceramide synthase UDP-galactose:beta-D-galactosyl-beta1-R 4-alpha-D-galactosyltransferase
Q0R0H6	Alpha-1,4-N-acetylglucosaminyltransferase Alpha-1,4-galactosyltransferase Globotriaosylceramide synthase UDP-galactose:beta-D-galactosyl-beta1-R 4-alpha-D-galactosyltransferase
Q67BJ4	Alpha-1,4-N-acetylglucosaminyltransferase Alpha-1,4-galactosyltransferase Alpha4Gal-T1 Globotriaosylceramide synthase UDP-galactose:beta-D-galactosyl-beta1-R 4-alpha-D-galactosyltransferase
Q3TRS1	Alpha-1,4-N-acetylglucosaminyltransferase Alpha-1,4-galactosyltransferase Globotriaosylceramide synthase UDP-galactose:beta-D-galactosyl-beta1-R 4-alpha-D-galactosyltransferase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
globoside biosynthetic process	IDA	16476743
globoside biosynthetic process	IMP	16476743 22875802
lipid metabolic process
glycosphingolipid biosynthetic process	IBA
plasma membrane organization	ISO

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

globoside metabolic process [inference]

globoside biosynthetic process

glycosphingolipid biosynthetic process

globoside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

carbohydrate derivative biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

cellular metabolic process [inference]

cellular biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

globoside metabolic process [inference]

globoside biosynthetic process

glycosphingolipid biosynthetic process

globoside biosynthetic process

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

sphingolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

globoside metabolic process [inference]

globoside biosynthetic process

glycosphingolipid biosynthetic process

globoside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

primary metabolic process [inference]

lipid metabolic process

lipid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

globoside metabolic process [inference]

globoside biosynthetic process

glycosphingolipid biosynthetic process

globoside biosynthetic process

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

sphingolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

globoside metabolic process [inference]

globoside biosynthetic process

glycosphingolipid biosynthetic process

globoside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

globoside metabolic process [inference]

globoside biosynthetic process

glycosphingolipid biosynthetic process

globoside biosynthetic process

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

organic substance metabolic process [inference]

lipid metabolic process

lipid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

globoside metabolic process [inference]

globoside biosynthetic process

glycosphingolipid biosynthetic process

globoside biosynthetic process

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

sphingolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

globoside metabolic process [inference]

globoside biosynthetic process

glycosphingolipid biosynthetic process

globoside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

globoside metabolic process [inference]

globoside biosynthetic process

glycosphingolipid biosynthetic process

globoside biosynthetic process

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

carbohydrate derivative metabolic process [inference]

carbohydrate derivative biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

globoside metabolic process [inference]

globoside biosynthetic process

glycosphingolipid biosynthetic process

globoside biosynthetic process

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

globoside metabolic process [inference]

globoside biosynthetic process

glycosphingolipid biosynthetic process

globoside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

carbohydrate derivative biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

globoside metabolic process [inference]

globoside biosynthetic process

glycosphingolipid biosynthetic process

globoside biosynthetic process

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

sphingolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

globoside metabolic process [inference]

globoside biosynthetic process

glycosphingolipid biosynthetic process

globoside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

cellular component organization or biogenesis [inference]

cellular component organization [inference]

membrane organization [inference]

plasma membrane organization

Displaying **all 2** entries
GO Term	Evidence Code	PMID
Golgi membrane	IEA
membrane	ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

organelle membrane [inference]

bounding membrane of organelle [inference]

Golgi membrane

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
galactosyltransferase activity	ISO
galactosyltransferase activity	IBA
toxic substance binding	IMP	16476743
hexosyltransferase activity
lactosylceramide 4-alpha-galactosyltransferase activity	IDA	16476743

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

UDP-glycosyltransferase activity [inference]

UDP-galactosyltransferase activity [inference]

lactosylceramide 4-alpha-galactosyltransferase activity

hexosyltransferase activity

galactosyltransferase activity

UDP-galactosyltransferase activity [inference]

lactosylceramide 4-alpha-galactosyltransferase activity

binding [inference]

toxic substance binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

mannosyltransferase

Functional Category

C: Energy production and conversion
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying **all 2** entries
InterPro
Glycosyltransferase, DXD sugar-binding motif
Nucleotide-diphospho-sugar transferases

KEGG BRITE Database

Orthology

K01988

Name

lactosylceramide 4-alpha-galactosyltransferase [EC:2.4.1.228]

References

10748143

Reactions

Displaying **all 3** entries
KEGG Reaction	Enzyme	Acceptor	Product
R11376	2.4.1.228	G00061MO	G33020YH
R11375	2.4.1.228	G58896AZ	G12460DL
R05960	2.4.1.228	G84224TW	G00059MO

Rhea

RHEA:11924

a β-D-Gal-(1→4)-β-D-Glc-(1↔1)-Cer(d18:1(4E)) + UDP-α-D-galactose

H⁺ + a globoside Gb3Cer (d18:1(4E)) + UDP

Enzyme

2.4.1.228

PMID

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP000275
Gene Name: alpha 1,4-galactosyltransferase

Ortholog

Displaying entries **1 - 10** of 69 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	33512	Xenbase:XB-GENE-493407
Xenopus tropicalis	43124	Xenbase:XB-GENE-493407
Drosophila melanogaster	51146	FB:FBgn0039378
Homo sapiens	53947	Xenbase:XB-GENE-493407	HUMAN60914
Rattus norvegicus	63888	Xenbase:XB-GENE-493407	RATNO38274
Xenopus tropicalis	239559	Xenbase:XB-GENE-493407
Drosophila melanogaster	333424	FB:FBgn0039378
Pan troglodytes	470230		PANTR26754
Drosophila melanogaster	549416	FB:FBgn0039378
Bos taurus	618369		BOVIN30808

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

KEGG BRITE Database

LIPID MAPS Gene / Proteome Database

International Collaboration

Acknowledgements