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alpha 1,4-galactosyltransferase

Summary

Gene Symbol

A4galt

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

239559

KEGG Gene ID

mmu:239559

PubChem

239559

Alliance of Genome Resources

MGI:3512453

Annotation

Keyword

Glycoprotein
Glycosyltransferase
Golgi apparatus
Lipid biosynthesis
Reference proteome
Signal-anchor
Transmembrane helix

Proteins

Displaying **all 4** entries
UniProt	Protein Name
Q3UF00	Alpha-1,4-N-acetylglucosaminyltransferase Alpha-1,4-galactosyltransferase Globotriaosylceramide synthase UDP-galactose:beta-D-galactosyl-beta1-R 4-alpha-D-galactosyltransferase
Q0R0H6	Alpha-1,4-N-acetylglucosaminyltransferase Alpha-1,4-galactosyltransferase Globotriaosylceramide synthase UDP-galactose:beta-D-galactosyl-beta1-R 4-alpha-D-galactosyltransferase
Q67BJ4	Alpha-1,4-N-acetylglucosaminyltransferase Alpha-1,4-galactosyltransferase Alpha4Gal-T1 Globotriaosylceramide synthase UDP-galactose:beta-D-galactosyl-beta1-R 4-alpha-D-galactosyltransferase
Q3TRS1	Alpha-1,4-N-acetylglucosaminyltransferase Alpha-1,4-galactosyltransferase Globotriaosylceramide synthase UDP-galactose:beta-D-galactosyl-beta1-R 4-alpha-D-galactosyltransferase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
plasma membrane organization	ISO
protein O-linked glycosylation	IBA
lipid metabolic process	IEA
globoside biosynthetic process	IDA IMP	16476743 22875802

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

globoside metabolic process [inference]

globoside biosynthetic process

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

carbohydrate derivative biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

cellular metabolic process [inference]

cellular biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

globoside metabolic process [inference]

globoside biosynthetic process

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

sphingolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

globoside metabolic process [inference]

globoside biosynthetic process

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

primary metabolic process [inference]

lipid metabolic process

lipid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

globoside metabolic process [inference]

globoside biosynthetic process

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

sphingolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

globoside metabolic process [inference]

globoside biosynthetic process

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

globoside metabolic process [inference]

globoside biosynthetic process

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein O-linked glycosylation

organic substance metabolic process [inference]

lipid metabolic process

lipid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

globoside metabolic process [inference]

globoside biosynthetic process

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

sphingolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

globoside metabolic process [inference]

globoside biosynthetic process

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

globoside metabolic process [inference]

globoside biosynthetic process

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein O-linked glycosylation

carbohydrate derivative metabolic process [inference]

carbohydrate derivative biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

globoside metabolic process [inference]

globoside biosynthetic process

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

globoside metabolic process [inference]

globoside biosynthetic process

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

carbohydrate derivative biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

globoside metabolic process [inference]

globoside biosynthetic process

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

sphingolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

globoside metabolic process [inference]

globoside biosynthetic process

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

globoside biosynthetic process

cellular component organization or biogenesis [inference]

cellular component organization [inference]

membrane organization [inference]

plasma membrane organization

Displaying **all 3** entries
GO Term	Evidence Code	PMID
membrane	ISO
Golgi apparatus	IEA
Golgi membrane

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

organelle membrane [inference]

bounding membrane of organelle [inference]

Golgi membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
glycosyltransferase activity	IEA
transferase activity	IEA
toxic substance binding	IMP	16476743
galactosyltransferase activity	IBA ISO
acetylglucosaminyltransferase activity	IBA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity

glycosyltransferase activity

UDP-glycosyltransferase activity [inference]

acetylglucosaminyltransferase activity

UDP-galactosyltransferase activity [inference]

lactosylceramide 4-alpha-galactosyltransferase activity

hexosyltransferase activity [inference]

acetylglucosaminyltransferase activity

galactosyltransferase activity

UDP-galactosyltransferase activity [inference]

lactosylceramide 4-alpha-galactosyltransferase activity

binding [inference]

toxic substance binding

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K01988

Name

lactosylceramide 4-alpha-galactosyltransferase [EC:2.4.1.228]

References

10748143

Reactions

Displaying **all 3** entries
KEGG Reaction	Enzyme	Acceptor	Product
R11375	2.4.1.228	G58896AZ	G12460DL
R05960	2.4.1.228	G84224TW	G00059MO
R11376	2.4.1.228	G00061MO	G33020YH

Rhea

RHEA:11924

a β-D-Gal-(1→4)-β-D-Glc-(1↔1)-Cer(d18:1(4E)) + UDP-α-D-galactose

H⁺ + a globoside Gb3Cer (d18:1(4E)) + UDP

Enzyme

2.4.1.228

PMID

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP000275
Gene Name: alpha 1,4-galactosyltransferase

Ortholog

Displaying entries **31 - 40** of 62 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Loxodonta africana	100654825		LOXAF04423
Equus caballus	102150730		HORSE25863
Sus scrofa	100524987		PIGXX24962
Bos taurus	618369		BOVIN30808
Capra hircus	102190112		CAPHI25844
Oryctolagus cuniculus	100347783		RABIT15044
Dipodomys ordii	105992037		DIPOR15625
Cricetulus griseus	100770462		CRIGR17465
Rattus norvegicus	63888	RGD:621583	RATNO38274
Cavia porcellus	100721247		CAVPO13227

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

KEGG BRITE Database

LIPID MAPS Gene / Proteome Database

International Collaboration

Acknowledgements