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dopamine receptor D2
Summary
- Gene Symbol
-
- Drd2
- Organism
- Rattus norvegicus (Norway rat)
Annotation
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| cellular response to ethanol | ||
| positive regulation of urine volume | ||
| release of sequestered calcium ion into cytosol | ||
| response to ethanol | ||
| temperature homeostasis |
GO Hierarchy
- pigmentation
biological process
cellular process [inference]
homeostatic process [inference]
response to stimulus [inference]
localization [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of phosphorus metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of signaling [inference]
regulation of signal transduction [inference]
regulation of trans-synaptic signaling [inference]
regulation of localization [inference]
regulation of transport [inference]
regulation of transmembrane transport [inference]
regulation of monoatomic ion transport [inference]
regulation of secretion [inference]
negative regulation of transport [inference]
regulation of amine transport [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
negative regulation of cellular process [inference]
negative regulation of response to stimulus [inference]
negative regulation of transport [inference]
regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
signal transduction [inference]
regulation of cell communication [inference]
regulation of signal transduction [inference]
regulation of trans-synaptic signaling [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of phosphorus metabolic process [inference]
regulation of transmembrane transport [inference]
positive regulation of cellular process [inference]
negative regulation of cellular process [inference]
regulation of cellular component organization [inference]
regulation of secretion by cell [inference]
regulation of multicellular organismal process [inference]
regulation of biological quality [inference]
regulation of molecular function [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| dendritic spine | ||
| membrane | ||
| endocytic vesicle | ||
| axon terminus | ||
| perikaryon |
| GO Term | Evidence Code | PMID |
|---|---|---|
| organic cyclic compound binding | ||
| heterotrimeric G-protein binding | ||
| dopamine neurotransmitter receptor activity, coupled via Gi/Go | ||
| dopamine binding | ||
| protein binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- Zinc finger, RING-type
- Functional Category
-
- G: Carbohydrate transport and metabolism
- M: Cell wall/membrane/envelope biogenesis
- X: Mobilome: prophages, transposons
| InterPro |
|---|
| Dopamine D2 receptor |
| Dopamine receptor family |
| G protein-coupled receptor, rhodopsin-like |
| GPCR, rhodopsin-like, 7TM |
Alliance of Genome Resources
- Expression
| Location | References |
|---|---|
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:1307 | dementia | |
| DOID:14330 | Parkinson's disease | |
| DOID:1574 | alcohol use disorder | |
| DOID:1596 | depressive disorder | |
| DOID:1742 | drug psychosis | |
| DOID:2030 | anxiety disorder | |
| DOID:2316 | brain ischemia | |
| DOID:251 | alcohol-induced mental disorder | |
| DOID:2559 | opiate dependence | |
| DOID:2560 | morphine dependence |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 1813 | HGNC:3023 | HUMAN09422 | ||
| 13489 | 10090_1:002e09 | MGI:94924 | MOUSE60647 | |
| 33007 | FB:FBgn0053517 | |||
| 179347 | WB:WBGene00001053 | |||
| 281126 | BOVIN06473 | |||
| 282557 | ZFIN:ZDB-GENE-021119-2 | DANRE08232 | ||
| 378719 | ZFIN:ZDB-GENE-030910-2 | |||
| 403701 | CANLF15278 | |||
| 451553 | PANTR04355 | |||
| 694181 | MACMU11300 |
