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MIRAGE
frizzled related protein

Summary
Gene Symbol
  • FRZB
Organism
Homo sapiens (human)
NCBI Gene
2487
PubChem
2487
Alliance of Genome Resources
Annotation
Keyword
  • Developmental protein
  • Differentiation
  • Direct protein sequencing
  • Disease variant
  • Disulfide bond
  • Glycoprotein
  • Reference proteome
  • Secreted
  • Signal
  • Wnt signaling pathway
Proteins
Displaying all 2 entries
UniProt Protein Name
D9ZGF6
  • Frizzled-related protein 1
  • FrzB-1
Q92765
  • Frezzled
  • Fritz
  • Frizzled-related protein 1
  • FrzB-1
Annotation information from UniProt.
Gene Ontology (GO)
Displaying entries 1 - 5 of 20 in total
GO Term Evidence Code PMID
skeletal system development
epithelial cell development
negative regulation of cell population proliferation
negative regulation of cell development
neural crest cell differentiation
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Eukaryota
Group Name
secreted frizzled-related protein
Functional Category
  • G: Carbohydrate transport and metabolism
  • O: Posttranslational modification, protein turnover, chaperones
  • T: Signal transduction mechanisms
Displaying all 4 entries
Gene Ontology
Wnt-protein binding
canonical Wnt signaling pathway
cell differentiation
non-canonical Wnt signaling pathway
Displaying all 6 entries
InterPro
Frizzled cysteine-rich domain superfamily
Frizzled domain
Frizzled/secreted frizzled-related protein
Netrin domain
Netrin module, non-TIMP type
Tissue inhibitor of metalloproteinases-like, OB-fold
Disease
Disease Ontology
Displaying all 2 entries
DO ID Disease Name Source
DOID:3908 lung non-small cell carcinoma
DOID:8398 osteoarthritis
Ortholog
Displaying entries 1 - 10 of 68 in total
Species Gene ID Alliance of Genome Resources Orthologous MAtrix
2487 Xenbase:XB-GENE-481353
20378 Xenbase:XB-GENE-481353 MOUSE33925
30119 DANRE44581
281170 BOVIN23941
295691 RATNO26119
706048 MACMU06031
742552 PANTR29303
100008629 RABIT11829
100027678 MONDO21096
100068206 HORSE13421
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025