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MIRAGE
Secreted frizzled-related protein 3

Summary
UniProt ID
Q92765
Gene Symbol
  • FIZ
  • FRE
  • FRP
  • FRZB
  • FRZB1
  • SFRP3
Gene ID
2487
Organism
Homo sapiens (human)
GlyConnect
GlyGen
Q92765
Re-Glyco
Q92765
Annotation
Keyword
  • Developmental protein
  • Differentiation
  • Direct protein sequencing
  • Disease variant
  • Disulfide bond
  • Glycoprotein
  • Reference proteome
  • Secreted
  • Signal
  • Wnt signaling pathway
Gene Ontology (GO)
Displaying all 3 entries
GO Term
extracellular space
cytoplasm
membrane
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying 1 entry
GO Term
Wnt-protein binding
Annotation information from UniProt.
Sequence
MVCGSPGGMLLLRAGLLALAALCLLRVPGARAAACEPVRIPLCKSLPWNMTKMPNHLHHSTQANAILAIEQFEGLLGTHCSPDLLFFLCAMYAPICTIDFQHEPIKPCKSVCERARQGCEPILIKYRHSWPENLACEELPVYDRGVCISPEAIVTADGADFPMDSSNGNCRGASSERCKCKPIRATQKTYFRNNYNYVIRAKVKEIKTKCHDVTAVVEVKEILKSSLVNIPRDTVNLYTSSGCLCPPLNVNEEYIIMGYEDEERSRLLLVEGSIAEKWKDRLGKKVKRWDMKLRHLGLSKSDSSNSDSTQSQKSGRNSNPRQARN
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying 1 entry
Position Description PubMed ID GlyTouCan ID Source
49 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Disease
Displaying all 2 entries
DO ID Disease Name Source
DOID:3908 lung non-small cell carcinoma
DOID:8398 osteoarthritis
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025