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Submissions

calcium voltage-gated channel subunit alpha1 A

Summary

Gene Symbol

Cacna1a

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

25398

PubChem

25398

Alliance of Genome Resources

RGD:2244

Annotation

Keyword

Alternative splicing
Calcium channel
Cell membrane
Disulfide bond
Glycoprotein
Metal-binding
Phosphoprotein
Reference proteome
Repeat
Transmembrane helix
Voltage-gated channel

Proteins

Displaying **all 2** entries
UniProt	Protein Name
O70368	Voltage-gated calcium channel subunit alpha Cav2.1
P54282	Brain calcium channel I Calcium channel, L type, alpha-1 polypeptide, isoform 4 Rat brain class A Voltage-gated calcium channel subunit alpha Cav2.1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 63 in total

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GO Term	Evidence Code	PMID
calcium ion transport	ISO
calcium ion transport	IDA	9593738
calcium ion transport	IMP	14673106
positive regulation of cytosolic calcium ion concentration	ISS
positive regulation of cytosolic calcium ion concentration	ISO

GO Hierarchy

biological process

metabolic process [inference]

biosynthetic process [inference]

hormone biosynthetic process

hormone metabolic process [inference]

hormone biosynthetic process

cellular process [inference]

cell communication [inference]

cell-cell signaling [inference]

gamma-aminobutyric acid signaling pathway

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission

cell death [inference]

programmed cell death [inference]

apoptotic process [inference]

neuron apoptotic process

vesicle-mediated transport [inference]

exocytosis [inference]

regulated exocytosis [inference]

synaptic vesicle exocytosis [inference]

calcium ion-regulated exocytosis of neurotransmitter

calcium-ion regulated exocytosis

calcium ion-regulated exocytosis of neurotransmitter

vesicle-mediated transport in synapse [inference]

synaptic vesicle exocytosis [inference]

calcium ion-regulated exocytosis of neurotransmitter

cellular developmental process [inference]

cell differentiation [inference]

cell differentiation in spinal cord [inference]

spinal cord motor neuron differentiation

cell differentiation in hindbrain [inference]

cerebellar Purkinje cell differentiation

neuron differentiation [inference]

central nervous system neuron differentiation

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

receptor clustering

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to membrane [inference]

receptor clustering

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to amyloid-beta

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to amyloid-beta

cellular response to oxygen-containing compound [inference]

cellular response to peptide [inference]

cellular response to amyloid-beta

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport

calcium ion transmembrane import into cytosol [inference]

calcium ion import across plasma membrane

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

calcium ion transmembrane transport

calcium ion transmembrane import into cytosol [inference]

calcium ion import across plasma membrane

inorganic cation import across plasma membrane [inference]

calcium ion import across plasma membrane

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

calcium ion import across plasma membrane

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

calcium ion import across plasma membrane

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

cell junction assembly [inference]

synapse assembly

cell projection organization [inference]

cell projection morphogenesis [inference]

plasma membrane bounded cell projection morphogenesis [inference]

neuron projection morphogenesis [inference]

dendrite morphogenesis

cell junction organization [inference]

cell junction assembly [inference]

synapse assembly

synapse organization [inference]

synapse assembly

export from cell [inference]

secretion by cell [inference]

exocytosis [inference]

regulated exocytosis [inference]

synaptic vesicle exocytosis [inference]

calcium ion-regulated exocytosis of neurotransmitter

calcium-ion regulated exocytosis

calcium ion-regulated exocytosis of neurotransmitter

signal release [inference]

signal release from synapse [inference]

synaptic vesicle exocytosis [inference]

calcium ion-regulated exocytosis of neurotransmitter

multicellular organismal process [inference]

system process [inference]

nervous system process

transmission of nerve impulse

neuromuscular process

musculoskeletal movement [inference]

musculoskeletal movement, spinal reflex action

neuromuscular process controlling balance

behavior [inference]

locomotory behavior [inference]

adult locomotory behavior [inference]

adult walking behavior

walking behavior [inference]

adult walking behavior

adult behavior [inference]

adult locomotory behavior [inference]

adult walking behavior

behavioral response to pain

multicellular organismal response to stress [inference]

response to pain

multicellular organismal movement [inference]

musculoskeletal movement [inference]

musculoskeletal movement, spinal reflex action

developmental process [inference]

anatomical structure morphogenesis [inference]

cellular anatomical entity morphogenesis [inference]

cell projection morphogenesis [inference]

plasma membrane bounded cell projection morphogenesis [inference]

neuron projection morphogenesis [inference]

dendrite morphogenesis

developmental maturation [inference]

anatomical structure maturation [inference]

cerebellum maturation

anatomical structure development [inference]

neural nucleus development [inference]

vestibular nucleus development

cellular developmental process [inference]

cell differentiation [inference]

cell differentiation in spinal cord [inference]

spinal cord motor neuron differentiation

cell differentiation in hindbrain [inference]

cerebellar Purkinje cell differentiation

neuron differentiation [inference]

central nervous system neuron differentiation

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic anion homeostasis [inference]

intracellular chloride ion homeostasis

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis [inference]

regulation of cytosolic calcium ion concentration [inference]

regulation of presynaptic cytosolic calcium ion concentration

neuron cellular homeostasis

regulation of presynaptic cytosolic calcium ion concentration

chemical homeostasis [inference]

carbohydrate homeostasis [inference]

glucose homeostasis

monoatomic ion homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic anion homeostasis [inference]

intracellular chloride ion homeostasis

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis [inference]

regulation of cytosolic calcium ion concentration [inference]

regulation of presynaptic cytosolic calcium ion concentration

monoatomic cation homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis [inference]

regulation of cytosolic calcium ion concentration [inference]

regulation of presynaptic cytosolic calcium ion concentration

calcium ion homeostasis [inference]

intracellular calcium ion homeostasis [inference]

regulation of cytosolic calcium ion concentration [inference]

regulation of presynaptic cytosolic calcium ion concentration

monoatomic anion homeostasis [inference]

intracellular monoatomic anion homeostasis [inference]

intracellular chloride ion homeostasis

chloride ion homeostasis [inference]

intracellular chloride ion homeostasis

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic anion homeostasis [inference]

intracellular chloride ion homeostasis

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis [inference]

regulation of cytosolic calcium ion concentration [inference]

regulation of presynaptic cytosolic calcium ion concentration

inorganic ion homeostasis [inference]

chloride ion homeostasis [inference]

intracellular chloride ion homeostasis

calcium ion homeostasis [inference]

intracellular calcium ion homeostasis [inference]

regulation of cytosolic calcium ion concentration [inference]

regulation of presynaptic cytosolic calcium ion concentration

response to stimulus [inference]

response to stress [inference]

multicellular organismal response to stress [inference]

response to pain

response to external stimulus [inference]

reflex [inference]

musculoskeletal movement, spinal reflex action

response to endogenous stimulus [inference]

cellular response to endogenous stimulus [inference]

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to amyloid-beta

response to chemical [inference]

response to organic substance [inference]

response to organonitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to amyloid-beta

response to peptide [inference]

cellular response to peptide [inference]

cellular response to amyloid-beta

response to amyloid-beta

cellular response to amyloid-beta

cellular response to organic substance [inference]

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to amyloid-beta

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to amyloid-beta

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to amyloid-beta

cellular response to oxygen-containing compound [inference]

cellular response to peptide [inference]

cellular response to amyloid-beta

response to nitrogen compound [inference]

response to organonitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to amyloid-beta

response to peptide [inference]

cellular response to peptide [inference]

cellular response to amyloid-beta

response to amyloid-beta

cellular response to amyloid-beta

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to amyloid-beta

response to oxygen-containing compound [inference]

response to peptide [inference]

cellular response to peptide [inference]

cellular response to amyloid-beta

response to amyloid-beta

cellular response to amyloid-beta

cellular response to oxygen-containing compound [inference]

cellular response to peptide [inference]

cellular response to amyloid-beta

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to amyloid-beta

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to amyloid-beta

cellular response to oxygen-containing compound [inference]

cellular response to peptide [inference]

cellular response to amyloid-beta

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to membrane [inference]

receptor clustering

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

calcium ion transport

calcium ion import

calcium ion transmembrane transport

calcium ion transmembrane import into cytosol [inference]

calcium ion import across plasma membrane

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport

calcium ion transmembrane import into cytosol [inference]

calcium ion import across plasma membrane

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport

calcium ion transmembrane import into cytosol [inference]

calcium ion import across plasma membrane

vesicle-mediated transport [inference]

exocytosis [inference]

regulated exocytosis [inference]

synaptic vesicle exocytosis [inference]

calcium ion-regulated exocytosis of neurotransmitter

calcium-ion regulated exocytosis

calcium ion-regulated exocytosis of neurotransmitter

vesicle-mediated transport in synapse [inference]

synaptic vesicle exocytosis [inference]

calcium ion-regulated exocytosis of neurotransmitter

secretion [inference]

secretion by cell [inference]

exocytosis [inference]

regulated exocytosis [inference]

synaptic vesicle exocytosis [inference]

calcium ion-regulated exocytosis of neurotransmitter

calcium-ion regulated exocytosis

calcium ion-regulated exocytosis of neurotransmitter

signal release [inference]

signal release from synapse [inference]

synaptic vesicle exocytosis [inference]

calcium ion-regulated exocytosis of neurotransmitter

acid secretion [inference]

gamma-aminobutyric acid secretion

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport

calcium ion transmembrane import into cytosol [inference]

calcium ion import across plasma membrane

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

calcium ion transmembrane transport

calcium ion transmembrane import into cytosol [inference]

calcium ion import across plasma membrane

inorganic cation import across plasma membrane [inference]

calcium ion import across plasma membrane

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

calcium ion import across plasma membrane

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

calcium ion import across plasma membrane

organic substance transport [inference]

calcium ion transport

calcium ion import

calcium ion transmembrane transport

calcium ion transmembrane import into cytosol [inference]

calcium ion import across plasma membrane

organic anion transport [inference]

carboxylic acid transport [inference]

amino acid transport [inference]

gamma-aminobutyric acid transport [inference]

gamma-aminobutyric acid secretion

organic acid transport [inference]

carboxylic acid transport [inference]

amino acid transport [inference]

gamma-aminobutyric acid transport [inference]

gamma-aminobutyric acid secretion

nitrogen compound transport [inference]

amino acid transport [inference]

gamma-aminobutyric acid transport [inference]

gamma-aminobutyric acid secretion

import into cell [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

calcium ion import across plasma membrane

export from cell [inference]

secretion by cell [inference]

exocytosis [inference]

regulated exocytosis [inference]

synaptic vesicle exocytosis [inference]

calcium ion-regulated exocytosis of neurotransmitter

calcium-ion regulated exocytosis

calcium ion-regulated exocytosis of neurotransmitter

signal release [inference]

signal release from synapse [inference]

synaptic vesicle exocytosis [inference]

calcium ion-regulated exocytosis of neurotransmitter

establishment of localization in cell

synaptic vesicle exocytosis [inference]

calcium ion-regulated exocytosis of neurotransmitter

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

receptor clustering

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to membrane [inference]

receptor clustering

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of hormone biosynthetic process

regulation of cellular biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of hormone biosynthetic process

regulation of hormone biosynthetic process [inference]

negative regulation of hormone biosynthetic process

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of hormone biosynthetic process

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of hormone biosynthetic process

negative regulation of hormone metabolic process [inference]

negative regulation of hormone biosynthetic process

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of hormone biosynthetic process

regulation of cellular biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of hormone biosynthetic process

regulation of hormone biosynthetic process [inference]

negative regulation of hormone biosynthetic process

regulation of sulfur metabolic process [inference]

regulation of sulfur amino acid metabolic process

regulation of hormone metabolic process [inference]

negative regulation of hormone metabolic process [inference]

negative regulation of hormone biosynthetic process

regulation of hormone biosynthetic process [inference]

negative regulation of hormone biosynthetic process

regulation of nitrogen compound metabolic process [inference]

regulation of sulfur amino acid metabolic process

regulation of small molecule metabolic process [inference]

regulation of sulfur amino acid metabolic process

regulation of signaling [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission

regulation of synaptic transmission, cholinergic [inference]

regulation of acetylcholine secretion, neurotransmission

regulation of neurotransmitter secretion [inference]

regulation of acetylcholine secretion, neurotransmission

rhythmic synaptic transmission

signaling [inference]

cell-cell signaling [inference]

gamma-aminobutyric acid signaling pathway

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission

regulation of localization [inference]

regulation of transport [inference]

regulation of transmembrane transport [inference]

regulation of transmembrane transporter activity [inference]

regulation of monoatomic ion transmembrane transporter activity [inference]

regulation of calcium ion transmembrane transporter activity [inference]

regulation of voltage-gated calcium channel activity

regulation of cation channel activity [inference]

regulation of voltage-gated calcium channel activity

regulation of monoatomic ion transmembrane transport [inference]

regulation of monoatomic cation transmembrane transport [inference]

regulation of calcium ion transmembrane transport [inference]

regulation of calcium ion transmembrane transporter activity [inference]

regulation of voltage-gated calcium channel activity

regulation of cation channel activity [inference]

regulation of voltage-gated calcium channel activity

regulation of monoatomic ion transport [inference]

regulation of metal ion transport [inference]

regulation of calcium ion transport [inference]

regulation of calcium ion transmembrane transport [inference]

regulation of calcium ion transmembrane transporter activity [inference]

regulation of voltage-gated calcium channel activity

regulation of monoatomic ion transmembrane transport [inference]

regulation of monoatomic cation transmembrane transport [inference]

regulation of calcium ion transmembrane transport [inference]

regulation of calcium ion transmembrane transporter activity [inference]

regulation of voltage-gated calcium channel activity

regulation of cation channel activity [inference]

regulation of voltage-gated calcium channel activity

regulation of secretion [inference]

regulation of secretion by cell [inference]

regulation of exocytosis [inference]

regulation of regulated secretory pathway [inference]

regulation of calcium ion-dependent exocytosis

regulation of neurotransmitter secretion [inference]

regulation of acetylcholine secretion, neurotransmission

regulation of neurotransmitter transport [inference]

regulation of neurotransmitter secretion [inference]

regulation of acetylcholine secretion, neurotransmission

regulation of amine transport [inference]

regulation of acetylcholine secretion, neurotransmission

regulation of vesicle-mediated transport [inference]

regulation of exocytosis [inference]

regulation of regulated secretory pathway [inference]

regulation of calcium ion-dependent exocytosis

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of hormone biosynthetic process

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of hormone biosynthetic process

negative regulation of hormone metabolic process [inference]

negative regulation of hormone biosynthetic process

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of hormone biosynthetic process

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of neuron apoptotic process

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of axonogenesis

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission

regulation of synaptic transmission, cholinergic [inference]

regulation of acetylcholine secretion, neurotransmission

regulation of neurotransmitter secretion [inference]

regulation of acetylcholine secretion, neurotransmission

rhythmic synaptic transmission

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of hormone biosynthetic process

regulation of cellular biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of hormone biosynthetic process

regulation of hormone biosynthetic process [inference]

negative regulation of hormone biosynthetic process

regulation of sulfur metabolic process [inference]

regulation of sulfur amino acid metabolic process

regulation of transmembrane transport [inference]

regulation of transmembrane transporter activity [inference]

regulation of monoatomic ion transmembrane transporter activity [inference]

regulation of calcium ion transmembrane transporter activity [inference]

regulation of voltage-gated calcium channel activity

regulation of cation channel activity [inference]

regulation of voltage-gated calcium channel activity

regulation of monoatomic ion transmembrane transport [inference]

regulation of monoatomic cation transmembrane transport [inference]

regulation of calcium ion transmembrane transport [inference]

regulation of calcium ion transmembrane transporter activity [inference]

regulation of voltage-gated calcium channel activity

regulation of cation channel activity [inference]

regulation of voltage-gated calcium channel activity

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

negative regulation of apoptotic process [inference]

negative regulation of neuron apoptotic process

regulation of neuron apoptotic process [inference]

negative regulation of neuron apoptotic process

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of neuron apoptotic process

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of hormone biosynthetic process

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of neuron apoptotic process

regulation of cellular component organization [inference]

regulation of cell projection organization [inference]

regulation of plasma membrane bounded cell projection organization [inference]

regulation of neuron projection development [inference]

regulation of axonogenesis

regulation of vesicle-mediated transport [inference]

regulation of exocytosis [inference]

regulation of regulated secretory pathway [inference]

regulation of calcium ion-dependent exocytosis

regulation of secretion by cell [inference]

regulation of exocytosis [inference]

regulation of regulated secretory pathway [inference]

regulation of calcium ion-dependent exocytosis

regulation of neurotransmitter secretion [inference]

regulation of acetylcholine secretion, neurotransmission

regulation of biological quality [inference]

positive regulation of cytosolic calcium ion concentration

regulation of hormone levels

regulation of hormone metabolic process [inference]

negative regulation of hormone metabolic process [inference]

negative regulation of hormone biosynthetic process

regulation of hormone biosynthetic process [inference]

negative regulation of hormone biosynthetic process

hormone metabolic process [inference]

hormone biosynthetic process

regulation of membrane potential

membrane depolarization

regulation of molecular function [inference]

regulation of transporter activity [inference]

regulation of transmembrane transporter activity [inference]

regulation of monoatomic ion transmembrane transporter activity [inference]

regulation of calcium ion transmembrane transporter activity [inference]

regulation of voltage-gated calcium channel activity

regulation of cation channel activity [inference]

regulation of voltage-gated calcium channel activity

Displaying entries **1 - 5** of 26 in total

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GO Term	Evidence Code	PMID
nucleus	ISO
nucleus	IEA
cytoplasm	ISO
cytoplasm	IEA
plasma membrane	ISO

GO Hierarchy

cellular component

protein-containing complex

membrane protein complex [inference]

plasma membrane protein complex [inference]

voltage-gated calcium channel complex

transmembrane transporter complex [inference]

monoatomic ion channel complex

cation channel complex [inference]

calcium channel complex [inference]

voltage-gated calcium channel complex

transporter complex [inference]

transmembrane transporter complex [inference]

monoatomic ion channel complex

cation channel complex [inference]

calcium channel complex [inference]

voltage-gated calcium channel complex

cellular anatomical entity [inference]

cytoplasm

membrane [inference]

plasma membrane

plasma membrane region [inference]

synaptic membrane [inference]

cell junction [inference]

synapse [inference]

glutamatergic synapse

somatodendritic compartment

cell projection

plasma membrane bounded cell projection [inference]

neuron projection [inference]

dendrite

perikaryon

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

cell body [inference]

neuronal cell body

neuron projection terminus [inference]

axon terminus [inference]

calyx of Held

presynapse [inference]

axon terminus [inference]

calyx of Held

Displaying entries **1 - 5** of 17 in total

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GO Term	Evidence Code	PMID
voltage-gated calcium channel activity	ISS
voltage-gated calcium channel activity	ISO
voltage-gated calcium channel activity	TAS	9593738
voltage-gated calcium channel activity	IDA	15980432 16049183 9593738
voltage-gated calcium channel activity	IEA

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic ion channel activity [inference]

voltage-gated monoatomic ion channel activity [inference]

voltage-gated monoatomic cation channel activity

voltage-gated calcium channel activity

high voltage-gated calcium channel activity

voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels [inference]

voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels

monoatomic cation channel activity [inference]

calcium channel activity

voltage-gated calcium channel activity

high voltage-gated calcium channel activity

voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels [inference]

voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels

voltage-gated monoatomic cation channel activity

voltage-gated calcium channel activity

high voltage-gated calcium channel activity

voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels [inference]

voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels

monoatomic cation transmembrane transporter activity [inference]

monoatomic cation channel activity [inference]

calcium channel activity

voltage-gated calcium channel activity

high voltage-gated calcium channel activity

voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels [inference]

voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels

voltage-gated monoatomic cation channel activity

voltage-gated calcium channel activity

high voltage-gated calcium channel activity

voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels [inference]

voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels

metal ion transmembrane transporter activity [inference]

calcium ion transmembrane transporter activity [inference]

calcium channel activity

voltage-gated calcium channel activity

high voltage-gated calcium channel activity

voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels [inference]

voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels

inorganic molecular entity transmembrane transporter activity [inference]

inorganic cation transmembrane transporter activity [inference]

metal ion transmembrane transporter activity [inference]

calcium ion transmembrane transporter activity [inference]

calcium channel activity

voltage-gated calcium channel activity

high voltage-gated calcium channel activity

voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels [inference]

voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels

passive transmembrane transporter activity [inference]

channel activity [inference]

monoatomic ion channel activity [inference]

voltage-gated monoatomic ion channel activity [inference]

voltage-gated monoatomic cation channel activity

voltage-gated calcium channel activity

high voltage-gated calcium channel activity

voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels [inference]

voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels

monoatomic cation channel activity [inference]

calcium channel activity

voltage-gated calcium channel activity

high voltage-gated calcium channel activity

voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels [inference]

voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels

voltage-gated monoatomic cation channel activity

voltage-gated calcium channel activity

high voltage-gated calcium channel activity

voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels [inference]

voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels

gated channel activity [inference]

voltage-gated channel activity [inference]

voltage-gated monoatomic ion channel activity [inference]

voltage-gated monoatomic cation channel activity

voltage-gated calcium channel activity

high voltage-gated calcium channel activity

voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels [inference]

voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels

salt transmembrane transporter activity [inference]

calcium ion transmembrane transporter activity [inference]

calcium channel activity

voltage-gated calcium channel activity

high voltage-gated calcium channel activity

voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels [inference]

voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels

binding [inference]

protein binding

SNARE binding [inference]

syntaxin binding

calmodulin binding

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

voltage-dependent calcium channel

Functional Category

E: Amino acid transport and metabolism
J: Translation, ribosomal structure and biogenesis
P: Inorganic ion transport and metabolism
T: Signal transduction mechanisms

Displaying **all 7** entries
Gene Ontology
calcium channel activity
calcium ion transmembrane transport
calcium ion transport
high voltage-gated calcium channel activity
metal ion binding
monoatomic ion channel activity
monoatomic ion transport

Displaying **all 2** entries
InterPro
Ion transport domain
Voltage-dependent channel domain superfamily

Alliance of Genome Resources

Expression

Displaying **all 3** entries
Location	References
protein-containing complex	PMID:17068255
perikaryon	PMID:16736476
voltage-gated calcium channel complex	PMID:16049183 PMID:21611731

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:1825	childhood absence epilepsy	Alliance of Genome Resources

Ortholog

Displaying entries **51 - 60** of 95 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Saccharomyces cerevisiae S288C	114493	SGD:S000003449
Saccharomyces cerevisiae S288C	114862	SGD:S000003449
Saccharomyces cerevisiae S288C	170581	SGD:S000003449
Saccharomyces cerevisiae S288C	259232	SGD:S000003449
Bos taurus	282648		BOVIN32470
Saccharomyces cerevisiae S288C	338370	SGD:S000003449
Saccharomyces cerevisiae S288C	403310	SGD:S000003449
Saccharomyces cerevisiae S288C	405791	SGD:S000003449
Pan troglodytes	455766		PANTR17359
Saccharomyces cerevisiae S288C	497770	SGD:S000003449

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements