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solute carrier family 2 member 3

Summary

Gene Symbol

Slc2a3

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

25551

PubChem

25551

Alliance of Genome Resources

RGD:3706

Annotation

Keyword

Cell membrane
Cell projection
Glycoprotein
Phosphoprotein
Reference proteome
Sugar transport
Transmembrane helix

Proteins

Displaying **all 4** entries
UniProt	Protein Name
A0A0G2JT05	Glucose transporter type 3
A0A0G2JSJ3	Glucose transporter type 3
Q07647	Glucose transporter type 3, brain
A6ILF8	Glucose transporter type 3

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
response to glucose	IEP	12882795
glucose import	IBA IDA	15320870
negative regulation of apoptotic process	IDA	15320870
transport across blood-brain barrier	ISO
dehydroascorbic acid transport	IBA IDA IEA ISO	18668520

GO Hierarchy

biological process

cellular process [inference]

transmembrane transport [inference]

carbohydrate transmembrane transport [inference]

monosaccharide transmembrane transport

hexose transmembrane transport [inference]

hexose import across plasma membrane [inference]

glucose import across plasma membrane

glucose transmembrane transport

carbohydrate import across plasma membrane [inference]

hexose import across plasma membrane [inference]

glucose import across plasma membrane

import across plasma membrane [inference]

carbohydrate import across plasma membrane [inference]

hexose import across plasma membrane [inference]

glucose import across plasma membrane

multicellular organismal process [inference]

system process [inference]

circulatory system process [inference]

vascular process in circulatory system [inference]

vascular transport [inference]

transport across blood-brain barrier

developmental process [inference]

anatomical structure development [inference]

cerebral cortex development

response to stimulus [inference]

response to chemical [inference]

response to organic substance [inference]

response to carbohydrate [inference]

response to monosaccharide [inference]

response to hexose [inference]

response to glucose

response to Thyroglobulin triiodothyronine

response to oxygen-containing compound [inference]

response to carbohydrate [inference]

response to monosaccharide [inference]

response to hexose [inference]

response to glucose

localization [inference]

establishment of localization [inference]

transport [inference]

vascular transport [inference]

transport across blood-brain barrier

vitamin transport [inference]

dehydroascorbic acid transport

transmembrane transport [inference]

carbohydrate transmembrane transport [inference]

monosaccharide transmembrane transport

hexose transmembrane transport [inference]

hexose import across plasma membrane [inference]

glucose import across plasma membrane

glucose transmembrane transport

carbohydrate import across plasma membrane [inference]

hexose import across plasma membrane [inference]

glucose import across plasma membrane

import across plasma membrane [inference]

carbohydrate import across plasma membrane [inference]

hexose import across plasma membrane [inference]

glucose import across plasma membrane

organic substance transport [inference]

carbohydrate transport [inference]

carbohydrate transmembrane transport [inference]

monosaccharide transmembrane transport

hexose transmembrane transport [inference]

hexose import across plasma membrane [inference]

glucose import across plasma membrane

glucose transmembrane transport

carbohydrate import across plasma membrane [inference]

hexose import across plasma membrane [inference]

glucose import across plasma membrane

organic anion transport [inference]

dehydroascorbic acid transport

import into cell [inference]

carbohydrate import across plasma membrane [inference]

hexose import across plasma membrane [inference]

glucose import across plasma membrane

biological regulation [inference]

regulation of biological process [inference]

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

regulation of cellular process [inference]

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

negative regulation of apoptotic process

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

negative regulation of cellular process [inference]

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
synaptic vesicle membrane	IDA	10318820
membrane	ISO ISS
acrosomal membrane	IEA ISO
perikaryon	IEA
plasma membrane	IBA IDA IEA ISO ISS	18668520 27881773

GO Hierarchy

cellular component

cellular anatomical entity [inference]

intracellular anatomical structure [inference]

inclusion body [inference]

aggresome

cytoplasm

membrane

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

transport vesicle membrane [inference]

exocytic vesicle membrane [inference]

synaptic vesicle membrane

secretory granule membrane [inference]

acrosomal membrane

bounding membrane of organelle [inference]

transport vesicle membrane [inference]

exocytic vesicle membrane [inference]

synaptic vesicle membrane

secretory granule membrane [inference]

acrosomal membrane

plasma membrane region [inference]

plasma membrane raft [inference]

caveola

synaptic membrane

membrane microdomain [inference]

membrane raft [inference]

plasma membrane raft [inference]

caveola

cell junction [inference]

synapse [inference]

glutamatergic synapse

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
kinase binding	IPI	16419038
protein binding	IPI	16419038
dehydroascorbic acid transmembrane transporter activity	IDA IEA ISO	18668520
monosaccharide transmembrane transporter activity	IDA	8645164
galactoside binding	IDA	8645164

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

organic anion transmembrane transporter activity [inference]

dehydroascorbic acid transmembrane transporter activity

carbohydrate transmembrane transporter activity [inference]

sugar transmembrane transporter activity [inference]

monosaccharide transmembrane transporter activity

hexose transmembrane transporter activity [inference]

glucose transmembrane transporter activity

D-glucose transmembrane transporter activity

vitamin transmembrane transporter activity [inference]

dehydroascorbic acid transmembrane transporter activity

binding [inference]

protein binding

enzyme binding [inference]

kinase binding

carbohydrate binding [inference]

monosaccharide binding [inference]

small molecule binding [inference]

monosaccharide binding [inference]

carbohydrate derivative binding [inference]

galactoside binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

solute carrier family 2, facilitated glucose transporter member 3

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
P: Inorganic ion transport and metabolism

Displaying **all 6** entries
Gene Ontology
D-glucose transmembrane transporter activity
dehydroascorbic acid transport
glucose binding
glucose import
hexose transmembrane transporter activity
organic substance transport

Displaying **all 7** entries
InterPro
Glucose transporter GLUT
Glucose transporter, type 3 (GLUT3)
MFS transporter superfamily
Major facilitator superfamily domain
Major facilitator, sugar transporter-like
Sugar transporter, conserved site
Sugar/inositol transporter

Alliance of Genome Resources

Expression

Displaying **all 2** entries
Location	References
synaptic vesicle membrane	PMID:10318820
caveola	PMID:16419038

Disease

Disease Ontology

Displaying **all 6** entries
DO ID	Disease Name	Source
DOID:10652	Alzheimer's disease	Alliance of Genome Resources
DOID:10763	hypertension	Alliance of Genome Resources
DOID:3138	acanthosis nigricans	Alliance of Genome Resources
DOID:83	cataract	Alliance of Genome Resources
DOID:9351	diabetes mellitus	Alliance of Genome Resources
DOID:9352	type 2 diabetes mellitus	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of **141** in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	6515		HGNC:11007	HUMAN10977
Mus musculus	20527	10090_1:001cc6	MGI:95757	MOUSE47724
Drosophila melanogaster	38109		FB:FBgn0264574
Homo sapiens	144195		HGNC:18301	HUMAN10958
Caenorhabditis elegans	173525		WB:WBGene00019207
Caenorhabditis elegans	178634		WB:WBGene00019979
Bos taurus	282358			BOVIN30344
Canis lupus familiaris	403997			CANLF11104
Danio rerio	436916		ZFIN:ZDB-GENE-040718-390	DANRE15073
Ovis aries	443308			SHEEP14947

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Summary

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Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements