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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
alkaline phosphatase, biomineralization associated
Summary
- Gene Symbol
-
- Alpl
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- Biomineralization
- Calcium
- Cell membrane
- Direct protein sequencing
- Disulfide bond
- GPI-anchor
- Hydrolase
- Magnesium
- Metal-binding
- Mitochondrion
- Phosphoprotein
- Reference proteome
- Signal
- Zinc
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| calcium ion homeostasis | ||
| bone mineralization | ||
| endochondral ossification | ||
| response to insulin | ||
| biomineral tissue development |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular matrix | ||
| mitochondrial membrane | ||
| extracellular membrane-bounded organelle | ||
| plasma membrane | ||
| side of membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| pyridoxal phosphatase activity | ||
| inorganic diphosphate phosphatase activity | ||
| alkaline phosphatase activity | ||
| pyrophosphatase activity | ||
| ATP hydrolysis activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- Alkaline phosphatase
- Functional Category
-
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
- V: Defense mechanisms
| Gene Ontology |
|---|
| alkaline phosphatase activity |
| dephosphorylation |
| hydrolase activity |
| metal ion binding |
| phosphoamidase activity |
| phosphoethanolamine phosphatase activity |
| pyridoxal phosphatase activity |
| InterPro |
|---|
| Alkaline phosphatase, active site |
| Alkaline phosphatase |
| Alkaline-phosphatase-like, core domain superfamily |
Alliance of Genome Resources
- Expression
| Location | References |
|---|---|
Rhea
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0110913 | adult hypophosphatasia | |
| DOID:0110914 | infantile hypophosphatasia | |
| DOID:0110915 | childhood hypophosphatasia | |
| DOID:13809 | familial combined hyperlipidemia | |
| DOID:14213 | hypophosphatasia | |
| DOID:2349 | arteriosclerosis | |
| DOID:4676 | uremia | |
| DOID:8719 | in situ carcinoma | |
| DOID:9452 | steatotic liver disease |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 100927335 | SARHA14096 | |||
| 100952679 | OTOGA16869 | |||
| 100987532 | PANPA00525 | |||
| 101001000 | PAPAN21110 | |||
| 101052916 | SAIBB24455 | |||
| 101123195 | SHEEP10053 | |||
| 101134160 | GORGO18052 | |||
| 101158849 | ORYLA14496 | |||
| 101327213 | TURTR01831 | |||
| 101587992 | 10160_0:002ce1 | OCTDE15741 |
