steatotic liver disease

Summary
Synonym
  • Fatty change of liver
  • SLD
  • Steatosis of liver
  • alcoholic fatty liver
  • fatty liver disease
  • hepatic lipidosis
  • hepatic steatosis
Definition
A lipid storage disease characterized by the accumulation of large vacuoles of triglyceride fat in at least 5% of hepatocytes.
Super Class
lipid storage disease liver disease
Disease Ontology
DOID:9452
Mondo Disease Ontology
MeSH
UMLS
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying all 6 entries
Gene ID Gene Symbol Description Source
154 ADRB2 adrenoceptor beta 2
1571 CYP2E1 cytochrome P450 family 2 subfamily E member 1
3030 HADHA hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha
3356 HTR2A 5-hydroxytryptamine receptor 2A
3357 HTR2B 5-hydroxytryptamine receptor 2B
80339 PNPLA3 patatin like domain 3, 1-acylglycerol-3-phosphate O-acyltransferase
Displaying all 4 entries
Gene ID Gene Symbol Description Source
16835 Ldlr low density lipoprotein receptor
16846 Lep leptin
16974 Lrp6 low density lipoprotein receptor-related protein 6
17202 Mc4r melanocortin 4 receptor
Displaying all 5 entries
Gene ID Gene Symbol Description Source
24385 Gck glucokinase
29527 Ptgs2 prostaglandin-endoperoxide synthase 2
83516 Ppargc1a PPARG coactivator 1 alpha
252900 Dgat2 diacylglycerol O-acyltransferase 2
300438 Ldlr low density lipoprotein receptor
Displaying 1 entry
Gene ID Gene Symbol Description Source
856386 LAG1 sphingosine N-acyltransferase LAG1

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: March 31, 2025