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Repository for lectin-assisted multimodality data
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MIRAGE
Low-density lipoprotein receptor
Summary
- UniProt ID
- P35952
- Gene Symbol
-
- Ldlr
- Gene ID
- 300438
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- Cell membrane
- Cholesterol metabolism
- Coated pit
- Disulfide bond
- EGF-like domain
- Endocytosis
- Endosome
- Glycoprotein
- Golgi apparatus
- LDL
- Lipid transport
- Lysosome
- Phosphoprotein
- Receptor
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| lysosome |
| plasma membrane |
| somatodendritic compartment |
| receptor complex |
| endosome |
| early endosome |
| late endosome |
| caveola |
| clathrin-coated pit |
| low-density lipoprotein particle |
Sequence
MSTADLMLRWAIALLLAAAGVAAEDSCGKNEFQCRDGKCIVSKWVCDGSRECPDGSDESPETCMSVTCRSGEFSCGGRVSRCIPDSWRCDGRTDCENGSDELDCSPKTCSLDEFRCQDGKCISRQFVCDQDWDCLDGSDEAHCAATTCGPAHFRCNSSSCIPSLWACDGDRDCDDGSDEWPQNCGAEDTAAEVVSSPCSSLEFHCGSSECIHRSWVCDGAADCKDKSDEENCAVTTCRPDEFQCADGSCIHGSRQCDREHDCKDMSDELGCINVTQCDGPNKFKCHSGECISLDKVCNSARDCRDWSDEPIKECKTNECLDNNGGCSHICKDLKIGYECLCPSGFRLVDGHQCEDIDECQEPDTCSQLCVNLEGSFKCECRAGFHMDPHTRVCKAVGSIGFLLFTNRHEVRKMTLDRSEYTSLIPNLKNVVALDTEVANNRIYWSDLSQRKIYSAVMDQGTSLSYDAIISGDLHAPDGLAVDWIHGNIYWTDSVPGTVSVADTKGVRRRTLFREKGSRPRAIVVDPVHGFMYWTDWGTPAKIKKGGLNGVDIYSLVTEDIQWPNGITLDLPSGRLYWVDSKLHSISSIDVNGGGRKTILEDEKQLAHPFSLAIYEDKVYWTDVLNEAIFSANRLTGSDVNLVAKNLMSPEDIVLFHNVTQPRGVNWCEATVLPNGGCQYMCLPAPQISAHSPKFTCACPDGMLLAKDMRSCLPEVDTVPTTQGTSTIGPVVTTSAAVSLKRKEDPSATRHKEDPSATRHNEDPSATSTSRQPGDTPELSTVESVTVSSQVQGDMAGRGDEVQRHGVGFLSIFLPIALVALLVFGAILLWRNWRLRNINSINFDNPVYQKTTEDEIHICRSQDGYTYPSRQMVSLEDDVA
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Cargo recognition for clathrin-mediated endocytosis | Rattus norvegicus |
| Chylomicron clearance | Rattus norvegicus |
| Clathrin-mediated endocytosis | Rattus norvegicus |
| LDL clearance | Rattus norvegicus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:10230 | aortic atherosclerosis | |
| DOID:1168 | familial hyperlipidemia | |
| DOID:1936 | atherosclerosis | |
| DOID:3345 | xanthomatosis | |
| DOID:9452 | steatotic liver disease |
