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Beta-2 adrenergic receptor

Summary

UniProt ID

P07550

Gene Symbol

ADRB2
ADRB2R
B2AR

Organism

Homo sapiens (human)

External Links

GlyGen: P07550
PubChem: P07550
The Human Metabolome Database: HMDBP01634
The O-GlcNAc Database: P07550

Annotation

Keyword

3D-structure
Cell membrane
Disulfide bond
Endosome
G-protein coupled receptor
Glycoprotein
Golgi apparatus
Hydroxylation
Palmitate
Phosphoprotein
Reference proteome
Transmembrane helix
Ubl conjugation

Gene Ontology (GO)

Displaying entries **1 - 10** of 33 in total

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GO Term
positive regulation of transcription by RNA polymerase II
diet induced thermogenesis
norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure
desensitization of G protein-coupled receptor signaling pathway by arrestin
endosome to lysosome transport
smooth muscle contraction
cell surface receptor signaling pathway
activation of transmembrane receptor protein tyrosine kinase activity
bone resorption
positive regulation of bone mineralization

Displaying entries **1 - 10** of 12 in total

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GO Term
endosome
endosome membrane
early endosome
nucleus
lysosome
Golgi apparatus
plasma membrane
membrane
receptor complex
apical plasma membrane

Displaying **all 8** entries
GO Term
protein-containing complex binding
norepinephrine binding
potassium channel regulator activity
identical protein binding
protein homodimerization activity
amyloid-beta binding
beta2-adrenergic receptor activity
adenylate cyclase binding

Annotation information from UniProt.

Sequence

MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQEAINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNTGEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 4** entries
Position	Description	GlyTouCan ID	Source
6	N-linked (GlcNAc...) asparagine		UniProt GlyGen
15	N-linked (GlcNAc...) asparagine		UniProt GlyGen
146		G49108TO	GlyGen The O-GlcNAc Database
187			GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 5** entries
Pathway Name	Organism
Adrenoceptors	Homo sapiens
Cargo recognition for clathrin-mediated endocytosis	Homo sapiens
Clathrin-mediated endocytosis	Homo sapiens
G alpha (s) signalling events	Homo sapiens
Ub-specific processing proteases	Homo sapiens