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Peroxisome proliferator-activated receptor gamma coactivator 1-alpha

Summary

UniProt ID

Q9QYK2

Gene Symbol

Pgc1
Pgc1a
Ppargc1
Ppargc1a

Gene ID

83516

Organism

Rattus norvegicus (Norway rat)

External Links

PubChem: Q9QYK2
The O-GlcNAc Database: Q9QYK2
Re-Glyco: Q9QYK2

Annotation

Keyword

Acetylation
Activator
Biological rhythms
Nucleus
Phosphoprotein
RNA-binding
Reference proteome
Transcription regulation
Ubl conjugation

Gene Ontology (GO)

Displaying **all 6** entries
GO Term
nucleus
euchromatin
neuronal cell body
PML body
cytosolic ribosome
apical dendrite

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

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GO Term
regulation of DNA-templated transcription
positive regulation of DNA-templated transcription
positive regulation of transcription by RNA polymerase II
response to dietary excess
response to fructose
response to electrical stimulus involved in regulation of muscle adaptation
response to leucine
positive regulation of fatty acid oxidation
flavone metabolic process
cellular response to fructose stimulus

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GO Term
chromatin binding
transcription coactivator activity
DNA binding
transcription coregulator activity
nuclear receptor binding
nuclear estrogen receptor binding
nuclear receptor coactivator activity
chromatin DNA binding
ubiquitin protein ligase binding
sequence-specific DNA binding

Annotation information from UniProt.

Sequence

MAWDMCSQDSVWSDIECAALVGEDQPLCPDLPELDLSELDVNDLDTDSFLGGLKWCSDQSEIISNQYNNEPANIFEKIDEENEANLLAVLTETLDSLPVDEDGLPSFDALTDGDVTTDNEASPSSMPDGTPPPQEAEEPSLLKKLLLAPANTQLSYNECSGLSTQNHANHTHRIRTNPAIVKTENSWSNKAKSICQQQKPQRRPCSELLKYLTTNDDPPHTKPTENRNSSRDKCASKKKSHTQPQSQHAQAKPTTLSLPLTPESPNDPKGSPFENKTIERTLSVELSGTAGLTPPTTPPHKANQDNPFKASPKLKPSCKTVVPPPTKRARYSECSGTQGSHSTKKGPEQSELYAQLSKSSVLSRGHEERKTKRPSLRLFGDHDYCQSVNSKTDILINISQELQDSRQLDFKDASCDWQGHICSSTDSSQCYLRETLEASKQVSPCSTRKQLQDQEIRAELNKHFGHPSQAVFDDKVDKTSELRDGNFSNEQFSKLPVFINSGLAMDGLFDDSEDENDKLSYPWDGTQSYSLFDVSPSCSSFNSPCRDSVSPPKSLFSQRPQRMRSRSRSFSRHRSCSRSPYSRSRSRSPGSRSSSRSCYYYESSHYRHRTHRNSPLYVRSRSRSPYSRRPRYDSYEANEHERLKRDEYRREYEKRESERAKQRERQKQKAIEERRVIYVGKIRPDTTRTELRDRFEVFGEIEECTVNLRDDGDSYGFITYRYTCDAFAALENGYTLRRSNETDFELYFCGRKQFFKSNYADLDSNSDDFDPASTKSKYDSLDFDSLLKEAQRSLRR

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
332			G49108TO	The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying 1 entry
Pathway Name	Organism
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis	Rattus norvegicus

Disease

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DO ID	Disease Name	Source
DOID:0060180	colitis	Alliance of Genome Resources
DOID:0080208	metabolic dysfunction-associated steatotic liver disease	Alliance of Genome Resources
DOID:10652	Alzheimer's disease	Alliance of Genome Resources
DOID:1074	kidney failure	Alliance of Genome Resources
DOID:114	heart disease	Alliance of Genome Resources
DOID:11446	sciatic neuropathy	Alliance of Genome Resources
DOID:12858	Huntington's disease	Alliance of Genome Resources
DOID:12930	dilated cardiomyopathy	Alliance of Genome Resources
DOID:4195	hyperglycemia	Alliance of Genome Resources
DOID:8947	diabetic retinopathy	Alliance of Genome Resources

GlyTouCan

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UniCarb-DR

LM-GlycoRepo

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External Links

Annotation

International Collaboration

Acknowledgements