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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
growth factor, augmenter of liver regeneration
Summary
- Gene Symbol
-
- GFER
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cataract
- Cytoplasm
- Deafness
- Disease variant
- Disulfide bond
- FAD
- Growth factor
- Mitochondrion
- Oxidoreductase
- Phosphoprotein
- Primary mitochondrial disease
- Reference proteome
- Secreted
- Proteins
| UniProt | Protein Name |
|---|---|
| P55789 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| positive regulation of DNA biosynthetic process | ||
| cellular response to toxic substance | ||
| liver regeneration | ||
| negative regulation of natural killer cell mediated cytotoxicity | ||
| negative regulation of apoptotic process |
GO Hierarchy
biological process
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of metabolic process [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| mitochondrion | ||
| mitochondrial intermembrane space | ||
| extracellular space | ||
| cytosol |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| protein-disulfide reductase activity | ||
| flavin-dependent sulfhydryl oxidase activity | ||
| growth factor activity | ||
| flavin adenine dinucleotide binding |
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- sulfhydryl oxidase
- Functional Category
-
- G: Carbohydrate transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| flavin adenine dinucleotide binding |
| flavin-dependent sulfhydryl oxidase activity |
| liver development |
| oxidoreductase activity |
| thiol oxidase activity |
| InterPro |
|---|
| ERV/ALR sulfhydryl oxidase domain superfamily |
| ERV/ALR sulfhydryl oxidase domain |
| Sulfhydryl oxidase ALR/ERV |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050855 | renal fibrosis | |
| DOID:0111216 | autosomal recessive centronuclear myopathy | |
| DOID:1074 | kidney failure | |
| DOID:11383 | cryptorchidism | |
| DOID:3021 | acute kidney failure | |
| DOID:5199 | ureteral obstruction | |
| DOID:898 | autosomal dominant polycystic kidney disease |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 11692 | MGI:107757 | MOUSE20400 | ||
| 27100 | RGD:61845 | RATNO00723 | ||
| 32991 | FB:FBgn0031068 | |||
| 171611 | WB:WBGene00018955 | |||
| 560433 | ZFIN:ZDB-GENE-060810-186 | DANRE31214 | ||
| 694203 | MACMU26926 | |||
| 733269 | Xenbase:XB-GENE-987618 | |||
| 750034 | 9598_0:004173 | PANTR11461 | ||
| 852916 | SGD:S000003261 | |||
| 100178035 | CIOIN14048 |
