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MIRAGE
apoptosis-inducing factor, mitochondrion-associated 1
Summary
- Gene Symbol
-
- Aifm1
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Alternative splicing
- Apoptosis
- Cytoplasm
- DNA-binding
- Direct protein sequencing
- FAD
- Isopeptide bond
- Mitochondrion inner membrane
- NAD
- Nucleus
- Oxidoreductase
- Phosphoprotein
- Proteomics identification
- Reference proteome
- Transit peptide
- Transmembrane helix
- Ubl conjugation
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| response to ischemia | ||
| apoptotic process | ||
| apoptotic process | ||
| activation of cysteine-type endopeptidase activity involved in apoptotic process |
|
|
| response to oxidative stress |
GO Hierarchy
biological process
cellular process [inference]
response to stimulus [inference]
response to stress [inference]
response to chemical [inference]
cellular response to stimulus [inference]
localization [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of primary metabolic process [inference]
positive regulation of biological process [inference]
regulation of molecular function [inference]
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| DNA binding | ||
| DNA binding | ||
| NADH dehydrogenase activity | ||
| electron-transferring-flavoprotein dehydrogenase activity | ||
| protein binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- apoptosis-inducing factor
- Functional Category
-
- E: Amino acid transport and metabolism
- G: Carbohydrate transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
| Gene Ontology |
|---|
| flavin adenine dinucleotide binding |
| oxidoreductase activity |
| InterPro |
|---|
| FAD/NAD(P)-binding domain superfamily |
| FAD/NAD(P)-binding domain |
| FAD/NAD-linked reductase, dimerisation domain superfamily |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060536 | mitochondrial complex I deficiency |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 9131 | Xenbase:XB-GENE-1016872 | HUMAN102137 | |
| 26926 | Xenbase:XB-GENE-1016872 | ||
| 51060 | Xenbase:XB-GENE-1016872 | ||
| 83533 | RATNO45050 | ||
| 481048 | CANLF20149 | ||
| 535714 | BOVIN36295 | ||
| 702773 | MACMU47373 | ||
| 768258 | FELCA39472 | ||
| 100021984 | MONDO36257 | ||
| 100054546 | HORSE43505 |
