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Apoptosis-inducing factor 1, mitochondrial

Summary

UniProt ID

Q9Z0X1

Gene Symbol

Aif
Aifm1
Pdcd8

Gene ID

26926

Organism

Mus musculus (house mouse)

External Links

GlyGen: Q9Z0X1
PubChem: Q9Z0X1
RaftProt: Q9Z0X1
Re-Glyco: Q9Z0X1

Annotation

Keyword

3D-structure
Acetylation
Alternative splicing
Apoptosis
Cytoplasm
DNA-binding
Direct protein sequencing
FAD
Isopeptide bond
Mitochondrion inner membrane
NAD
Nucleus
Oxidoreductase
Phosphoprotein
Reference proteome
Transit peptide
Ubl conjugation

Gene Ontology (GO)

Displaying **all 8** entries
GO Term
nucleus
cytoplasm
mitochondrion
mitochondrial inner membrane
cytosol
perinuclear region of cytoplasm
mitochondrial outer membrane
mitochondrial intermembrane space

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 19 in total

1

2

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GO Term
response to ischemia
response to oxidative stress
neuron apoptotic process
cellular response to hydrogen peroxide
cellular response to hypoxia
response to toxic substance
positive regulation of apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
apoptotic mitochondrial changes
mitochondrial respiratory chain complex assembly

Displaying **all 7** entries
GO Term
poly-ADP-D-ribose binding
DNA binding
electron-transferring-flavoprotein dehydrogenase activity
protein dimerization activity
FAD binding
NADH dehydrogenase activity
NAD(P)H oxidase H2O2-forming activity

Annotation information from UniProt.

Sequence

MFRCGGLAGAFKQKLVPLVRTVYVQRPKQRNRLPGNLFQQWRVPLELQMARQMASSGSSGGKMDNSVLVLIVGLSTIGAGAYAYKTIKEDQKRYNERVMGLGLSPEEKQRRAIASATEGGSVPQIRAPSHVPFLLIGGGTAAFAAARSIRARDPGARVLIVSEDPELPYMRPPLSKELWFSDDPNVTKTLQFRQWNGKERSIYFQPPSFYVSAQDLPNIENGGVAVLTGKKVVHLDVRGNMVKLNDGSQITFEKCLIATGGTPRSLSAIDRAGAEVKSRTTLFRKIGDFRALEKISREVKSITVIGGGFLGSELACALGRKSQASGIEVIQLFPEKGNMGKILPQYLSNWTMEKVKREGVKVMPNAIVQSVGVSGGRLLIKLKDGRKVETDHIVTAVGLEPNVELAKTGGLEIDSDFGGFRVNAELQARSNIWVAGDAACFYDIKLGRRRVEHHDHAVVSGRLAGENMTGAAKPYWHQSMFWSDLGPDVGYEAIGLVDSSLPTVGVFAKATAQDNPKSATEQSGTGIRSESETESEASEITIPPSAPAVPQVPVEGEDYGKGVIFYLRDKVVVGIVLWNVFNRMPIARKIIKDGEQHEDLNEVAKLFNIHED

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites