GlyCosmos Portal

Submissions

ADAM metallopeptidase with thrombospondin type 1 motif 16

Summary

Gene Symbol

Adamts16

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

271127

PubChem

271127

Alliance of Genome Resources

MGI:2429637

Annotation

Keyword

Alternative splicing
Cleavage on pair of basic residues
Disulfide bond
Extracellular matrix
Glycoprotein
Metal-binding
Metalloprotease
Reference proteome
Repeat
Signal
Zinc
Zymogen

Proteins

Displaying 1 entry
UniProt	Protein Name
Q69Z28

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
proteolysis	IBA IEA
male gamete generation	IEA ISO
branching involved in ureteric bud morphogenesis	IMP	23661704
regulation of systemic arterial blood pressure	IEA ISO
regulation of cilium assembly	IEA ISO

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

proteolysis

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis

cellular process [inference]

cellular component organization or biogenesis [inference]

cellular component organization [inference]

extracellular structure organization [inference]

extracellular matrix organization

external encapsulating structure organization [inference]

extracellular matrix organization

reproductive process [inference]

multicellular organismal reproductive process [inference]

gamete generation [inference]

male gamete generation

multicellular organismal process [inference]

morphogenesis of a branching structure [inference]

morphogenesis of a branching epithelium [inference]

branching morphogenesis of an epithelial tube [inference]

branching involved in ureteric bud morphogenesis

developmental process [inference]

anatomical structure morphogenesis [inference]

morphogenesis of a branching structure [inference]

morphogenesis of a branching epithelium [inference]

branching morphogenesis of an epithelial tube [inference]

branching involved in ureteric bud morphogenesis

tube morphogenesis [inference]

branching morphogenesis of an epithelial tube [inference]

branching involved in ureteric bud morphogenesis

tissue morphogenesis [inference]

morphogenesis of an epithelium [inference]

morphogenesis of a branching epithelium [inference]

branching morphogenesis of an epithelial tube [inference]

branching involved in ureteric bud morphogenesis

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

regulation of cellular component biogenesis [inference]

regulation of cell projection assembly [inference]

regulation of plasma membrane bounded cell projection assembly [inference]

regulation of cilium assembly

regulation of organelle assembly [inference]

regulation of cilium assembly

regulation of cellular component organization [inference]

regulation of cell projection organization [inference]

regulation of cell projection assembly [inference]

regulation of plasma membrane bounded cell projection assembly [inference]

regulation of cilium assembly

regulation of plasma membrane bounded cell projection organization [inference]

regulation of plasma membrane bounded cell projection assembly [inference]

regulation of cilium assembly

regulation of organelle organization [inference]

regulation of organelle assembly [inference]

regulation of cilium assembly

regulation of biological quality [inference]

regulation of blood pressure [inference]

regulation of systemic arterial blood pressure

Displaying **all 2** entries
GO Term	Evidence Code	PMID
extracellular matrix	IBA
extracellular region	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular region

external encapsulating structure [inference]

extracellular matrix

Displaying **all 2** entries
GO Term	Evidence Code	PMID
metal ion binding	IEA
metalloendopeptidase activity	IBA IEA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

peptidase activity [inference]

endopeptidase activity [inference]

metalloendopeptidase activity

metallopeptidase activity [inference]

metalloendopeptidase activity

catalytic activity, acting on a protein [inference]

peptidase activity [inference]

endopeptidase activity [inference]

metalloendopeptidase activity

metallopeptidase activity [inference]

metalloendopeptidase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

Thrombospondin type-1 (TSP1) repeat

Functional Category

I: Lipid transport and metabolism
T: Signal transduction mechanisms

Displaying **all 6** entries
Gene Ontology
extracellular matrix organization
hydrolase activity
metal ion binding
metalloendopeptidase activity
metallopeptidase activity
proteolysis

Displaying **all 10** entries
InterPro
ADAMTS, cysteine-rich domain 2
ADAMTS/ADAMTS-like, Spacer 1
ADAMTS/ADAMTS-like, cysteine-rich domain 3
ADAMTS/ADAMTS-like
Metallopeptidase, catalytic domain superfamily
PLAC
Peptidase M12B, ADAM/reprolysin
Peptidase M12B, propeptide
Thrombospondin type-1 (TSP1) repeat superfamily
Thrombospondin type-1 (TSP1) repeat

Disease

Disease Ontology

Displaying **all 3** entries
DO ID	Disease Name	Source
DOID:10763	hypertension	Alliance of Genome Resources
DOID:11383	cryptorchidism	Alliance of Genome Resources
DOID:12336	male infertility	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 98 in total

1

2

3

4

5

…

Next ›

Last »
Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	37619		FB:FBgn0086408
Homo sapiens	170690		HGNC:17108	HUMAN78561
Rattus norvegicus	306664	10116_1:0004a1	RGD:1310046	RATNO15746
Pan troglodytes	471451			PANTR35017
Bos taurus	520133			BOVIN16200
Danio rerio	568792			DANRE11462
Macaca mulatta	694474			MACMU38539
Monodelphis domestica	100017054			MONDO20363
Equus caballus	100071544			HORSE20581
Ornithorhynchus anatinus	100080561			ORNAN30544

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements