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integrin subunit alpha V

Summary

Gene Symbol

ITGAV

Organism

Bos taurus (domestic cattle)

External Links

NCBI Gene: 281875
PubChem: 281875

Annotation

Keyword

Calcium
Cell adhesion
Cell junction
Cell membrane
Cleavage on pair of basic residues
Direct protein sequencing
Disulfide bond
Glycoprotein
Host cell receptor for virus entry
Host-virus interaction
Integrin
Metal-binding
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
P80746	Vitronectin receptor subunit alpha
A0A3Q1MXS2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
cell-matrix adhesion	IEA	30032202
cell-cell adhesion	IEA	30032202
cell adhesion mediated by integrin	IEA	30032202
integrin-mediated signaling pathway	IEA	30032202
angiogenesis	IEA	30032202

GO Hierarchy

biological process

cellular process [inference]

cell adhesion [inference]

cell-substrate adhesion [inference]

cell-matrix adhesion

signal transduction [inference]

cell surface receptor signaling pathway [inference]

integrin-mediated signaling pathway

developmental process [inference]

anatomical structure formation involved in morphogenesis [inference]

angiogenesis

anatomical structure development [inference]

blood vessel development

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

integrin-mediated signaling pathway

Displaying **all 5** entries
GO Term	Evidence Code	PMID
external side of plasma membrane	IEA	30032202
integrin alphav-beta8 complex
focal adhesion
integrin alphav-beta6 complex
integrin complex	IEA	22301074 30032202

GO Hierarchy

cellular component

protein-containing complex [inference]

receptor complex [inference]

plasma membrane signaling receptor complex [inference]

integrin complex

protein complex involved in cell adhesion [inference]

integrin complex

membrane protein complex [inference]

plasma membrane protein complex [inference]

plasma membrane signaling receptor complex [inference]

integrin complex

cellular anatomical entity [inference]

cell junction [inference]

anchoring junction [inference]

cell-substrate junction [inference]

focal adhesion

side of membrane [inference]

external side of plasma membrane

Displaying **all 3** entries
GO Term	Evidence Code	PMID
integrin binding	IEA	30032202
metal ion binding
virus receptor activity

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

integrin binding

cell adhesion molecule binding [inference]

integrin binding

exogenous protein binding [inference]

virus receptor activity

ion binding [inference]

cation binding [inference]

metal ion binding

protein-containing complex binding [inference]

integrin binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

integrin

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying **all 4** entries
Gene Ontology
cell adhesion mediated by integrin
cell-matrix adhesion
integrin binding
integrin-mediated signaling pathway

Displaying **all 7** entries
InterPro
FG-GAP repeat
Integrin alpha beta-propellor
Integrin alpha chain
Integrin alpha, N-terminal
Integrin alpha, first immunoglubulin-like domain
Integrin alpha, second immunoglobulin-like domain
Integrin domain superfamily

Ortholog

Displaying entries **1 - 10** of 92 in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Homo sapiens	3685		HUMAN65925
Mus musculus	16410		MOUSE34001
Rattus norvegicus	296456		RATNO25867
Sus scrofa	397285	9823_0:00437a	PIGXX09620
Ovis aries	443143	9940_0:000d3b	SHEEP09342
Pan troglodytes	459807		PANTR29329
Canis lupus familiaris	488437		CANLF14037
Macaca mulatta	707756		MACMU06307
Oryctolagus cuniculus	100008956		RABIT11838
Monodelphis domestica	100028127		MONDO21357