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MIRAGE
cytochrome P450 family 2 subfamily E member 1

Summary
Gene Symbol
  • CYP2E1
Organism
Bos taurus (domestic cattle)
NCBI Gene
282213
KEGG Gene ID
bta:282213
PubChem
282213
Annotation
Keyword
  • Fatty acid metabolism
  • Heme
  • Microsome
  • Mitochondrion inner membrane
  • Monooxygenase
  • NADP
  • Reference proteome
  • Transmembrane helix
Proteins
Displaying all 2 entries
UniProt Protein Name
Q2TBV4
O18963
  • 4-nitrophenol 2-hydroxylase
  • CYPIIE1
Annotation information from UniProt.
Gene Ontology (GO)
Displaying all 2 entries
GO Term Evidence Code PMID
xenobiotic metabolic process
epoxygenase P450 pathway
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Eukaryota
Group Name
CYTOCHROME P450
Functional Category
  • I: Lipid transport and metabolism
  • Q: Secondary metabolites biosynthesis, transport and catabolism
  • T: Signal transduction mechanisms
Displaying all 6 entries
Gene Ontology
heme binding
iron ion binding
metal ion binding
monooxygenase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
oxidoreductase activity
Displaying all 4 entries
InterPro
Cytochrome P450 superfamily
Cytochrome P450, E-class, group I
Cytochrome P450, conserved site
Cytochrome P450
KEGG BRITE Database
Orthology
K07415
Name
cytochrome P450 family 2 subfamily E1 [EC:1.14.14.-]
References
Rhea

RHEA:26205

H+ + O2 + NADPH + 4-nitrophenol
H2O + 4-nitrocatechol + NADP+
Enzyme
PMID

RHEA:17149

an organic molecule + O2
H2O + H+ + an alcohol
Enzyme
PMID
Ortholog
Displaying entries 1 - 10 of 53 in total
Species Gene ID Alliance of Genome Resources Orthologous MAtrix
1571 HUMAN03501
13106 MOUSE56695
25086 RATNO19827
403216 PIGXX08765
415128 CANLF11620
450857 PANTR01866
554227 FELCA26840
554344 FELCA26840
678688 MACMU00260
100015828 MONDO01628
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025