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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
filamin, beta
Summary
- Gene Symbol
-
- Flnb
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Acetylation
- Actin-binding
- Cytoskeleton
- Isopeptide bond
- Phosphoprotein
- Reference proteome
- Repeat
- Ubl conjugation
- Proteins
| UniProt | Protein Name |
|---|---|
| Q80X90 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| actin cytoskeleton organization | ||
| keratinocyte development | ||
| skeletal muscle tissue development | ||
| cellular response to type II interferon | ||
| epithelial cell morphogenesis |
| GO Term | Evidence Code | PMID |
|---|---|---|
| cell cortex | ||
| focal adhesion | ||
| neuronal cell body | ||
| plasma membrane | ||
| brush border |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| actin filament binding | ||
| identical protein binding |
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- filamin-B
- Functional Category
-
- H: Coenzyme transport and metabolism
- M: Cell wall/membrane/envelope biogenesis
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| actin binding |
| actin cytoskeleton organization |
| actin filament binding |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050648 | atelosteogenesis | |
| DOID:0050680 | Boomerang dysplasia | |
| DOID:0060564 | spinal disease | |
| DOID:0080006 | bone development disease | |
| DOID:0080096 | myofibrillar myopathy 5 | |
| DOID:0090116 | spondylocarpotarsal synostosis syndrome | |
| DOID:0111190 | distal myopathy 4 | |
| DOID:11836 | clubfoot | |
| DOID:14764 | Larsen syndrome | |
| DOID:2256 | osteochondrodysplasia |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 2317 | HGNC:3755 | HUMAN70715 | ||
| 42066 | FB:FBgn0014141 | |||
| 176855 | WB:WBGene00022048 | |||
| 306204 | 10116_1:00460b | RGD:1311915 | RATNO09979 | |
| 460476 | PANTR31422 | |||
| 484713 | CANLF07393 | |||
| 563023 | ZFIN:ZDB-GENE-041026-1 | |||
| 613533 | BOVIN17603 | |||
| 702732 | MACMU29600 | |||
| 100008760 | RABIT12951 |
