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SET domain containing 2, histone lysine methyltransferase

Summary

Gene Symbol

SETD2

Organism

Homo sapiens (human)

External Links

NCBI Gene

29072

PubChem

29072

Alliance of Genome Resources

HGNC:18420

Annotation

Keyword

3D-structure
Activator
Alternative splicing
Antiviral defense
Autism spectrum disorder
Chromatin regulator
Chromosome
Coiled coil
DNA repair
Developmental protein
Differentiation
Disease variant
Host-virus interaction
Innate immunity
Intellectual disability
Isopeptide bond
Metal-binding
Methyltransferase
Nucleus
Phosphoprotein
Reference proteome
S-adenosyl-L-methionine
Transcription regulation
Tumor suppressor
Ubl conjugation
Zinc

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9BYW2	HIF-1 Huntingtin yeast partner B Huntingtin-interacting protein 1 Huntingtin-interacting protein B Lysine N-methyltransferase 3A Protein-lysine N-methyltransferase SETD2 SET domain-containing protein 2 p231HBP

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 33 in total

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GO Term	Evidence Code	PMID
angiogenesis	IEA
morphogenesis of a branching structure	IEA
neural tube closure	IEA
mismatch repair	IMP	23622243
regulation of transcription, DNA-templated	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

mismatch repair

RNA metabolic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein alkylation [inference]

protein methylation [inference]

peptidyl-lysine methylation [inference]

peptidyl-lysine trimethylation

peptidyl-amino acid modification [inference]

peptidyl-lysine modification [inference]

peptidyl-lysine methylation [inference]

peptidyl-lysine trimethylation

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

methylation [inference]

macromolecule methylation [inference]

protein methylation [inference]

peptidyl-lysine methylation [inference]

peptidyl-lysine trimethylation

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

mismatch repair

RNA metabolic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

mismatch repair

RNA metabolic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

mismatch repair

RNA metabolic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

mismatch repair

RNA metabolic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

protein metabolic process [inference]

protein modification process [inference]

protein alkylation [inference]

protein methylation [inference]

peptidyl-lysine methylation [inference]

peptidyl-lysine trimethylation

peptidyl-amino acid modification [inference]

peptidyl-lysine modification [inference]

peptidyl-lysine methylation [inference]

peptidyl-lysine trimethylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

protein metabolic process [inference]

protein modification process [inference]

protein alkylation [inference]

protein methylation [inference]

peptidyl-lysine methylation [inference]

peptidyl-lysine trimethylation

peptidyl-amino acid modification [inference]

peptidyl-lysine modification [inference]

peptidyl-lysine methylation [inference]

peptidyl-lysine trimethylation

macromolecule modification [inference]

protein modification process [inference]

protein alkylation [inference]

protein methylation [inference]

peptidyl-lysine methylation [inference]

peptidyl-lysine trimethylation

peptidyl-amino acid modification [inference]

peptidyl-lysine modification [inference]

peptidyl-lysine methylation [inference]

peptidyl-lysine trimethylation

macromolecule methylation [inference]

protein methylation [inference]

peptidyl-lysine methylation [inference]

peptidyl-lysine trimethylation

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

mismatch repair

RNA metabolic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

mismatch repair

RNA metabolic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein alkylation [inference]

protein methylation [inference]

peptidyl-lysine methylation [inference]

peptidyl-lysine trimethylation

peptidyl-amino acid modification [inference]

peptidyl-lysine modification [inference]

peptidyl-lysine methylation [inference]

peptidyl-lysine trimethylation

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

cellular process [inference]

microtubule-based process [inference]

microtubule cytoskeleton organization [inference]

microtubule cytoskeleton organization involved in mitosis

cell cycle process [inference]

mitotic cell cycle process [inference]

microtubule cytoskeleton organization involved in mitosis

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

mismatch repair

RNA metabolic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

mismatch repair

RNA metabolic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

mismatch repair

RNA metabolic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

cellular developmental process [inference]

cell differentiation [inference]

cell development [inference]

stem cell development

cell motility [inference]

cell migration [inference]

cell migration involved in vasculogenesis

cellular response to stimulus [inference]

cellular response to stress [inference]

DNA damage response [inference]

DNA repair [inference]

mismatch repair

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

microtubule cytoskeleton organization [inference]

microtubule cytoskeleton organization involved in mitosis

protein-containing complex organization [inference]

protein-DNA complex organization [inference]

chromatin organization [inference]

chromatin remodeling [inference]

nucleosome organization

multicellular organismal process [inference]

morphogenesis of a branching structure

developmental process [inference]

anatomical structure morphogenesis [inference]

morphogenesis of a branching structure

animal organ morphogenesis [inference]

embryonic organ morphogenesis [inference]

embryonic skeletal system morphogenesis [inference]

embryonic cranial skeleton morphogenesis

skeletal system morphogenesis [inference]

embryonic skeletal system morphogenesis [inference]

embryonic cranial skeleton morphogenesis

tube morphogenesis [inference]

blood vessel morphogenesis [inference]

coronary vasculature morphogenesis

embryonic morphogenesis [inference]

embryonic organ morphogenesis [inference]

embryonic skeletal system morphogenesis [inference]

embryonic cranial skeleton morphogenesis

embryonic placenta morphogenesis

tissue morphogenesis [inference]

mesoderm morphogenesis

anatomical structure formation involved in morphogenesis [inference]

angiogenesis

tube formation [inference]

tube closure [inference]

neural tube closure

anatomical structure development [inference]

tissue development [inference]

epithelium development [inference]

pericardium development

forebrain development

cell development [inference]

stem cell development

cellular developmental process [inference]

cell differentiation [inference]

cell development [inference]

stem cell development

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to virus [inference]

defense response to virus

defense response to other organism [inference]

defense response to symbiont [inference]

defense response to virus

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to other organism [inference]

defense response to symbiont [inference]

defense response to virus

cellular response to stress [inference]

DNA damage response [inference]

DNA repair [inference]

mismatch repair

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to virus [inference]

defense response to virus

defense response to other organism [inference]

defense response to symbiont [inference]

defense response to virus

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to virus [inference]

defense response to virus

defense response to other organism [inference]

defense response to symbiont [inference]

defense response to virus

response to chemical [inference]

response to organic substance [inference]

response to organonitrogen compound [inference]

response to alkaloid

response to organic cyclic compound

response to cytokine [inference]

response to type I interferon

response to inorganic substance [inference]

response to metal ion

response to nitrogen compound [inference]

response to organonitrogen compound [inference]

response to alkaloid

cellular response to stimulus [inference]

cellular response to stress [inference]

DNA damage response [inference]

DNA repair [inference]

mismatch repair

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of interferon-alpha production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of interferon-alpha production

regulation of type I interferon production [inference]

positive regulation of type I interferon production [inference]

positive regulation of interferon-alpha production

regulation of interferon-alpha production [inference]

positive regulation of interferon-alpha production

regulation of transcription, DNA-templated

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of interferon-alpha production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of interferon-alpha production

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of interferon-alpha production

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of interferon-alpha production

positive regulation of catabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of autophagy

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of interferon-alpha production

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of interferon-alpha production

positive regulation of cellular catabolic process [inference]

positive regulation of autophagy

regulation of catabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of autophagy

regulation of cellular catabolic process [inference]

regulation of autophagy [inference]

positive regulation of autophagy

positive regulation of cellular catabolic process [inference]

positive regulation of autophagy

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of DNA metabolic process [inference]

regulation of DNA recombination [inference]

regulation of double-strand break repair via homologous recombination

regulation of DNA repair [inference]

regulation of double-strand break repair [inference]

regulation of double-strand break repair via homologous recombination

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of interferon-alpha production

positive regulation of cellular catabolic process [inference]

positive regulation of autophagy

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of interferon-alpha production

regulation of type I interferon production [inference]

positive regulation of type I interferon production [inference]

positive regulation of interferon-alpha production

regulation of interferon-alpha production [inference]

positive regulation of interferon-alpha production

regulation of transcription, DNA-templated

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of interferon-alpha production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of interferon-alpha production

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of interferon-alpha production

regulation of cellular catabolic process [inference]

regulation of autophagy [inference]

positive regulation of autophagy

positive regulation of cellular catabolic process [inference]

positive regulation of autophagy

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of DNA metabolic process [inference]

regulation of DNA recombination [inference]

regulation of double-strand break repair via homologous recombination

regulation of DNA repair [inference]

regulation of double-strand break repair [inference]

regulation of double-strand break repair via homologous recombination

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of interferon-alpha production

regulation of type I interferon production [inference]

positive regulation of type I interferon production [inference]

positive regulation of interferon-alpha production

regulation of interferon-alpha production [inference]

positive regulation of interferon-alpha production

regulation of transcription, DNA-templated

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of interferon-alpha production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of interferon-alpha production

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of interferon-alpha production

regulation of DNA metabolic process [inference]

regulation of DNA recombination [inference]

regulation of double-strand break repair via homologous recombination

regulation of DNA repair [inference]

regulation of double-strand break repair [inference]

regulation of double-strand break repair via homologous recombination

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of DNA metabolic process [inference]

regulation of DNA recombination [inference]

regulation of double-strand break repair via homologous recombination

regulation of DNA repair [inference]

regulation of double-strand break repair [inference]

regulation of double-strand break repair via homologous recombination

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of localization [inference]

regulation of transport [inference]

regulation of nucleobase-containing compound transport [inference]

regulation of RNA export from nucleus [inference]

regulation of mRNA export from nucleus

regulation of intracellular transport [inference]

regulation of nucleocytoplasmic transport [inference]

regulation of RNA export from nucleus [inference]

regulation of mRNA export from nucleus

regulation of cellular localization [inference]

regulation of intracellular transport [inference]

regulation of nucleocytoplasmic transport [inference]

regulation of RNA export from nucleus [inference]

regulation of mRNA export from nucleus

regulation of protein localization [inference]

regulation of protein localization to chromatin

regulation of ribonucleoprotein complex localization [inference]

regulation of mRNA export from nucleus

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of interferon-alpha production

positive regulation of catabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of autophagy

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of interferon-alpha production

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of interferon-alpha production

positive regulation of cellular catabolic process [inference]

positive regulation of autophagy

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of interferon-alpha production

positive regulation of cellular catabolic process [inference]

positive regulation of autophagy

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of interferon-alpha production

positive regulation of ossification

regulation of response to stimulus [inference]

regulation of response to stress [inference]

regulation of cellular response to stress [inference]

regulation of DNA repair [inference]

regulation of double-strand break repair [inference]

regulation of double-strand break repair via homologous recombination

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of DNA metabolic process [inference]

regulation of DNA recombination [inference]

regulation of double-strand break repair via homologous recombination

regulation of DNA repair [inference]

regulation of double-strand break repair [inference]

regulation of double-strand break repair via homologous recombination

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of interferon-alpha production

positive regulation of cellular catabolic process [inference]

positive regulation of autophagy

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of interferon-alpha production

regulation of type I interferon production [inference]

positive regulation of type I interferon production [inference]

positive regulation of interferon-alpha production

regulation of interferon-alpha production [inference]

positive regulation of interferon-alpha production

regulation of transcription, DNA-templated

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of interferon-alpha production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of interferon-alpha production

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of interferon-alpha production

regulation of cellular catabolic process [inference]

regulation of autophagy [inference]

positive regulation of autophagy

positive regulation of cellular catabolic process [inference]

positive regulation of autophagy

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of interferon-alpha production

positive regulation of cellular catabolic process [inference]

positive regulation of autophagy

regulation of cell division [inference]

regulation of cytokinesis

regulation of cell cycle [inference]

regulation of cell cycle process [inference]

regulation of cytokinesis

regulation of cellular localization [inference]

regulation of intracellular transport [inference]

regulation of nucleocytoplasmic transport [inference]

regulation of RNA export from nucleus [inference]

regulation of mRNA export from nucleus

regulation of protein localization [inference]

regulation of protein localization to chromatin

regulation of ribonucleoprotein complex localization [inference]

regulation of mRNA export from nucleus

regulation of cellular response to stress [inference]

regulation of DNA repair [inference]

regulation of double-strand break repair [inference]

regulation of double-strand break repair via homologous recombination

regulation of multicellular organismal process [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of interferon-alpha production

regulation of type I interferon production [inference]

positive regulation of type I interferon production [inference]

positive regulation of interferon-alpha production

regulation of interferon-alpha production [inference]

positive regulation of interferon-alpha production

regulation of ossification [inference]

positive regulation of ossification

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of interferon-alpha production

positive regulation of ossification

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
nucleus	ISS
nucleus	IBA
nucleoplasm	TAS
chromosome	ISS
chromosome	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

chromosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular non-membrane-bounded organelle [inference]

chromosome

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GO Term	Evidence Code	PMID
protein binding	IPI	17500595 19141475 21988832 28753426 36537238
protein-lysine N-methyltransferase activity	IDA	28753426
alpha-tubulin binding	IDA	27518565
metal ion binding	IEA
histone H3K36 methyltransferase activity	IDA	23043551 24843002 26002201 27474439 28753426

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring one-carbon groups [inference]

methyltransferase activity [inference]

N-methyltransferase activity [inference]

lysine N-methyltransferase activity [inference]

protein-lysine N-methyltransferase activity

histone H3K36 methyltransferase activity

histone H3K36 trimethyltransferase activity

protein methyltransferase activity [inference]

protein-lysine N-methyltransferase activity

histone H3K36 methyltransferase activity

histone H3K36 trimethyltransferase activity

histone methyltransferase activity [inference]

histone H3 methyltransferase activity

histone H3K36 methyltransferase activity

histone H3K36 trimethyltransferase activity

S-adenosylmethionine-dependent methyltransferase activity [inference]

lysine N-methyltransferase activity [inference]

protein-lysine N-methyltransferase activity

histone H3K36 methyltransferase activity

histone H3K36 trimethyltransferase activity

catalytic activity, acting on a protein [inference]

protein methyltransferase activity [inference]

protein-lysine N-methyltransferase activity

histone H3K36 methyltransferase activity

histone H3K36 trimethyltransferase activity

histone methyltransferase activity [inference]

histone H3 methyltransferase activity

histone H3K36 methyltransferase activity

histone H3K36 trimethyltransferase activity

histone modifying activity [inference]

histone methyltransferase activity [inference]

histone H3 methyltransferase activity

histone H3K36 methyltransferase activity

histone H3K36 trimethyltransferase activity

binding [inference]

protein binding

cytoskeletal protein binding [inference]

tubulin binding [inference]

alpha-tubulin binding

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Histone-lysine N-methyltransferase

Functional Category

C: Energy production and conversion
J: Translation, ribosomal structure and biogenesis
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
histone H3K36 methyltransferase activity
histone methyltransferase activity
methylation
transferase activity

Displaying **all 4** entries
InterPro
AWS domain
Post-SET domain
SET domain superfamily
SET domain

Disease

Disease Ontology

Displaying **all 8** entries
DO ID	Disease Name	Source
DOID:0050156	idiopathic pulmonary fibrosis	Alliance of Genome Resources
DOID:0060307	autosomal dominant intellectual developmental disorder	Alliance of Genome Resources
DOID:1790	malignant mesothelioma	Alliance of Genome Resources
DOID:3910	lung adenocarcinoma	Alliance of Genome Resources
DOID:4467	clear cell renal cell carcinoma	Alliance of Genome Resources
DOID:7474	malignant pleural mesothelioma	Alliance of Genome Resources
DOID:9253	gastrointestinal stromal tumor	Alliance of Genome Resources
DOID:9256	colorectal cancer	Alliance of Genome Resources

Ortholog

Displaying entries **11 - 20** of 81 in total

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Species	Gene ID	Orthologous MAtrix
Bos taurus	539860	BOVIN17943
Macaca mulatta	711825	MACMU28642
Danio rerio	794199	DANRE10909
Monodelphis domestica	100024848	MONDO28719
Equus caballus	100064888	HORSE12210
Taeniopygia guttata	100224614	TAEGU18197
Callithrix jacchus	100411953	CALJA12098
Pongo abelii	100433116	PONAB25101
Ailuropoda melanoleuca	100466135	AILME19366
Anolis carolinensis	100559621	ANOCA11188

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements