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synapsin II

Summary

Gene Symbol

Syn2

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

29179

PubChem

29179

Alliance of Genome Resources

RGD:3798

Annotation

Keyword

3D-structure
Alternative splicing
Direct protein sequencing
Phosphoprotein
Reference proteome
Synapse

Proteins

Displaying 1 entry
UniProt	Protein Name
Q63537	Synapsin II

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
synaptic vesicle clustering	IBA IEA ISO
synaptic vesicle cycle	ISO
synapse organization	IBA
neurotransmitter secretion	IEA ISO ISS
regulation of neurotransmitter secretion	TAS	2506642

GO Hierarchy

biological process

cellular process [inference]

vesicle-mediated transport [inference]

exocytosis [inference]

regulated exocytosis [inference]

calcium-ion regulated exocytosis

vesicle-mediated transport in synapse [inference]

synaptic vesicle cycle

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell junction organization [inference]

synapse organization

export from cell [inference]

secretion by cell [inference]

exocytosis [inference]

regulated exocytosis [inference]

calcium-ion regulated exocytosis

signal release [inference]

signal release from synapse [inference]

neurotransmitter secretion

localization [inference]

establishment of localization [inference]

transport [inference]

neurotransmitter transport [inference]

neurotransmitter secretion

vesicle-mediated transport [inference]

exocytosis [inference]

regulated exocytosis [inference]

calcium-ion regulated exocytosis

vesicle-mediated transport in synapse [inference]

synaptic vesicle cycle

secretion [inference]

secretion by cell [inference]

exocytosis [inference]

regulated exocytosis [inference]

calcium-ion regulated exocytosis

signal release [inference]

signal release from synapse [inference]

neurotransmitter secretion

export from cell [inference]

secretion by cell [inference]

exocytosis [inference]

regulated exocytosis [inference]

calcium-ion regulated exocytosis

signal release [inference]

signal release from synapse [inference]

neurotransmitter secretion

establishment of localization in cell [inference]

organelle localization [inference]

vesicle localization [inference]

synaptic vesicle localization [inference]

synaptic vesicle clustering

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of neurotransmitter secretion

regulation of localization [inference]

regulation of transport [inference]

regulation of secretion [inference]

regulation of secretion by cell [inference]

regulation of neurotransmitter secretion

regulation of neurotransmitter transport [inference]

regulation of neurotransmitter secretion

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of neurotransmitter secretion

regulation of secretion by cell [inference]

regulation of neurotransmitter secretion

Displaying entries **6 - 10** of 11 in total

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GO Term	Evidence Code	PMID
plasma membrane	IEA ISO
extrinsic component of synaptic vesicle membrane	EXP IDA IMP	2118908 23622064
synapse	ISO ISS
SNARE complex	IEA ISO
synaptic vesicle	IDA TAS	11867766 2506642

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

SNARE complex

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

transport vesicle membrane [inference]

exocytic vesicle membrane [inference]

synaptic vesicle membrane

bounding membrane of organelle [inference]

transport vesicle membrane [inference]

exocytic vesicle membrane [inference]

synaptic vesicle membrane

extrinsic component of membrane [inference]

extrinsic component of organelle membrane [inference]

extrinsic component of synaptic vesicle membrane

cell junction [inference]

synapse

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

postsynaptic specialization [inference]

postsynaptic density

presynapse

terminal bouton

Displaying **all 5** entries
GO Term	Evidence Code	PMID
protein binding	IPI	11867766 17442889
calcium-dependent protein binding	IPI	10567243
identical protein binding	IEA ISO
ATP binding	IEA
cytoskeletal protein binding	TAS	2506642

GO Hierarchy

molecular function

binding [inference]

protein binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

Synapsin

Functional Category

N: Cell motility
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
ATP binding

Displaying **all 3** entries
InterPro
Synapsin, ATP-binding domain
Synapsin, conserved site
Synapsin

Disease

Disease Ontology

Displaying **all 3** entries
DO ID	Disease Name	Source
DOID:0060041	autism spectrum disorder	Alliance of Genome Resources
DOID:1826	epilepsy	Alliance of Genome Resources
DOID:5419	schizophrenia	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 63 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	6854		HGNC:11495
Mus musculus	20965	10090_1:001ed2	MGI:103020	MOUSE50319
Drosophila melanogaster	41247		FB:FBgn0004575
Caenorhabditis elegans	176987		WB:WBGene00004913
Danio rerio	436870		ZFIN:ZDB-GENE-040718-341	DANRE23986
Danio rerio	641578		ZFIN:ZDB-GENE-051127-49
Taeniopygia guttata	751980			TAEGU03458
Salmo salar	100136520			SALSA38744
Xenopus tropicalis	100490046		Xenbase:XB-GENE-959237
Loxodonta africana	100654690			LOXAF14938