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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
major histocompatibility complex, class II, DQ alpha 2
Summary
- Gene Symbol
-
- HLA-DQA2
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Cell membrane
- Disulfide bond
- Endoplasmic reticulum
- Endosome
- Glycoprotein
- Golgi apparatus
- Lysosome
- MHC II
- Reference proteome
- Signal
- Transmembrane helix
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| antigen processing and presentation of exogenous peptide antigen via MHC class II | ||
| positive regulation of immune response | ||
| peptide antigen assembly with MHC class II protein complex | ||
| adaptive immune response | ||
| immune response |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| transport vesicle membrane | ||
| MHC class II protein complex | ||
| endocytic vesicle membrane | ||
| plasma membrane | ||
| trans-Golgi network membrane |
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| MHC class II protein complex binding | ||
| MHC class II receptor activity | ||
| peptide antigen binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- HLA class II histocompatibility antigen, DO alpha chain
- Functional Category
-
- M: Cell wall/membrane/envelope biogenesis
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| adaptive immune response |
| antigen processing and presentation of peptide or polysaccharide antigen via MHC class II |
| immune response |
| immune system process |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:13141 | uveitis | |
| DOID:2841 | asthma |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 14960 | MGI:95895 | MOUSE20169 | ||
| 282494 | BOVIN18692 | |||
| 282535 | BOVIN18687 | |||
| 309621 | RGD:1595867 | RATNO21825 | ||
| 368614 | ZFIN:ZDB-GENE-030616-505 | |||
| 471976 | 9598_0:001d14 | PANTR37846 | ||
| 474861 | CANLF02605 | |||
| 571282 | ZFIN:ZDB-GENE-081105-52 | |||
| 100026007 | MONDO11906 | |||
| 100026112 | MONDO11955 |
