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HLA class II histocompatibility antigen, DQ alpha 2 chain
Summary
- UniProt ID
- P01906
- Gene Symbol
-
- HLA-DQA2
- HLA-DXA
- Gene ID
- 3118
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Cell membrane
- Disulfide bond
- Endoplasmic reticulum
- Endosome
- Glycoprotein
- Golgi apparatus
- Lysosome
- MHC II
- Reference proteome
- Signal
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| MHC class II protein complex binding |
| MHC class II receptor activity |
| peptide antigen binding |
Sequence
MILNKALLLGALALTAVMSPCGGEDIVADHVASYGVNFYQSHGPSGQYTHEFDGDEEFYVDLETKETVWQLPMFSKFISFDPQSALRNMAVGKHTLEFMMRQSNSTAATNEVPEVTVFSKFPVTLGQPNTLICLVDNIFPPVVNITWLSNGHSVTEGVSETSFLSKSDHSFFKISYLTFLPSADEIYDCKVEHWGLDEPLLKHWEPEIPAPMSELTETLVCALGLSVGLMGIVVGTVFIIQGLRSVGASRHQGLL
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Downstream TCR signaling | Homo sapiens |
| Generation of second messenger molecules | Homo sapiens |
| Interferon gamma signaling | Homo sapiens |
| MHC class II antigen presentation | Homo sapiens |
| PD-1 signaling | Homo sapiens |
| Phosphorylation of CD3 and TCR zeta chains | Homo sapiens |
| Translocation of ZAP-70 to Immunological synapse | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:2841 | asthma |
