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GO Term	Evidence Code	PMID
MAP kinase kinase kinase kinase activity	ISO
enzyme binding	IEA
receptor tyrosine kinase binding	ISO
ubiquitin protein ligase binding	IPI	30760025
histone kinase activity	IDA	16125722

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

protein kinase activity [inference]

protein serine/threonine kinase activity

MAP kinase activity

MAP kinase kinase kinase activity

JUN kinase kinase kinase activity

MAP kinase kinase kinase kinase activity

protein serine/threonine/tyrosine kinase activity [inference]

MAP kinase kinase activity

phosphotransferase activity, alcohol group as acceptor [inference]

protein kinase activity [inference]

protein serine/threonine kinase activity

MAP kinase activity

MAP kinase kinase kinase activity

JUN kinase kinase kinase activity

MAP kinase kinase kinase kinase activity

protein serine/threonine/tyrosine kinase activity [inference]

MAP kinase kinase activity

catalytic activity, acting on a protein [inference]

protein kinase activity [inference]

protein serine/threonine kinase activity

MAP kinase activity

MAP kinase kinase kinase activity

JUN kinase kinase kinase activity

MAP kinase kinase kinase kinase activity

protein serine/threonine/tyrosine kinase activity [inference]

MAP kinase kinase activity

histone modifying activity [inference]

histone kinase activity

binding [inference]

protein binding

signaling receptor binding [inference]

cytokine receptor binding [inference]

transforming growth factor beta receptor binding [inference]

type II transforming growth factor beta receptor binding

receptor tyrosine kinase binding

transcription factor binding [inference]

transcription coregulator binding [inference]

transcription coactivator binding

DNA-binding transcription factor binding

enzyme binding

kinase binding [inference]

protein kinase binding [inference]

protein serine/threonine kinase binding

protein tyrosine kinase binding [inference]

receptor tyrosine kinase binding

ubiquitin-like protein ligase binding [inference]

ubiquitin protein ligase binding

ubiquitin-like protein binding [inference]

ubiquitin binding [inference]

linear polyubiquitin binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

cation binding [inference]

metal ion binding [inference]

magnesium ion binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

Mitogen-activated protein kinase kinase kinase 7

Functional Category

D: Cell cycle control, cell division, chromosome partitioning
J: Translation, ribosomal structure and biogenesis
T: Signal transduction mechanisms

Displaying **all 10** entries
Gene Ontology
ATP binding
JNK cascade
immune response
kinase activity
magnesium ion binding
metal ion binding
nucleotide binding
phosphorylation
positive regulation of canonical NF-kappaB signal transduction
transferase activity

Displaying **all 7** entries
InterPro
Mitogen-activated protein (MAP) kinase kinase kinase 7-like
Mitogen-activated protein kinase kinase kinase 7
Protein kinase domain
Protein kinase, ATP binding site
Protein kinase-like domain superfamily
Serine-threonine/tyrosine-protein kinase, catalytic domain
Serine/threonine-protein kinase, active site

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:2349	arteriosclerosis	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 81 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	6885	Xenbase:XB-GENE-481530	HUMAN85792
Mus musculus	26409	Xenbase:XB-GENE-481530	MOUSE42368
Xenopus tropicalis	313121	Xenbase:XB-GENE-481530
Pan troglodytes	462888		PANTR38711
Bos taurus	529146		BOVIN35676
Danio rerio	553788		DANRE18992
Macaca mulatta	703101		MACMU33403
Monodelphis domestica	100019975		MONDO12228
Equus caballus	100065841		HORSE01106
Sus scrofa	100135663		PIGXX13693

GlyTouCan

GlyComb

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LM-GlycoRepo

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OrthoDB (Group)

International Collaboration

Acknowledgements