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domeless

Summary

Gene Symbol

dome

Organism

Drosophila melanogaster (fruit fly)

External Links

NCBI Gene

32976

PubChem

32976

Alliance of Genome Resources

FB:FBgn0043903

Annotation

Keyword

Cell membrane
Developmental protein
Disulfide bond
Glycoprotein
Phosphoprotein
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9VWE0	Protein domeless

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **6 - 10** of 14 in total

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GO Term	Evidence Code	PMID
wing disc morphogenesis	IMP	28045022
locomotor rhythm	IMP	22305007
compound eye morphogenesis	IMP	15170700
cytokine-mediated signaling pathway	IGI	16277982
receptor signaling pathway via JAK-STAT	IDA IGI IMP	11696329 11825879 16094372 17855388 19520911 20841381 26658615 31072879 32917740 35905720

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

cytokine-mediated signaling pathway

receptor signaling pathway via STAT [inference]

receptor signaling pathway via JAK-STAT

cellular process involved in reproduction in multicellular organism [inference]

follicle cell of egg chamber migration [inference]

border follicle cell migration

cell motility [inference]

cell migration [inference]

ameboidal-type cell migration [inference]

epithelial cell migration [inference]

follicle cell of egg chamber migration [inference]

border follicle cell migration

reproductive process [inference]

cellular process involved in reproduction in multicellular organism [inference]

follicle cell of egg chamber migration [inference]

border follicle cell migration

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

cognition [inference]

learning or memory [inference]

memory [inference]

long-term memory

pattern specification process [inference]

regionalization [inference]

segmentation [inference]

blastoderm segmentation

specification of symmetry [inference]

determination of bilateral symmetry [inference]

determination of left/right symmetry [inference]

determination of digestive tract left/right asymmetry

embryonic pattern specification [inference]

blastoderm segmentation

behavior [inference]

learning or memory [inference]

memory [inference]

long-term memory

rhythmic behavior [inference]

circadian behavior [inference]

locomotor rhythm

locomotory behavior [inference]

locomotor rhythm

developmental process [inference]

anatomical structure morphogenesis [inference]

hindgut morphogenesis

animal organ morphogenesis [inference]

imaginal disc morphogenesis [inference]

wing disc morphogenesis

sensory organ morphogenesis [inference]

eye morphogenesis [inference]

compound eye morphogenesis

anatomical structure development [inference]

regeneration [inference]

tissue regeneration

system development [inference]

respiratory system development [inference]

open tracheal system development

growth [inference]

developmental growth [inference]

tissue regeneration

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium [inference]

defense response to Gram-negative bacterium

defense response to other organism [inference]

defense response to bacterium [inference]

defense response to Gram-negative bacterium

rhythmic process [inference]

circadian rhythm [inference]

circadian behavior [inference]

locomotor rhythm

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to other organism [inference]

defense response to bacterium [inference]

defense response to Gram-negative bacterium

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium [inference]

defense response to Gram-negative bacterium

defense response to other organism [inference]

defense response to bacterium [inference]

defense response to Gram-negative bacterium

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium [inference]

defense response to Gram-negative bacterium

defense response to other organism [inference]

defense response to bacterium [inference]

defense response to Gram-negative bacterium

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

cytokine-mediated signaling pathway

receptor signaling pathway via STAT [inference]

receptor signaling pathway via JAK-STAT

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

Displaying **all 3** entries
GO Term	Evidence Code	PMID
apicolateral plasma membrane
apical plasma membrane	IDA	12403714 18424141
plasma membrane

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

plasma membrane region [inference]

Displaying entry **6 - 6** of 6 in total

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GO Term	Evidence Code	PMID
SOCS family protein binding	IPI	23885117

GO Hierarchy

molecular function

binding [inference]

protein binding

transcription factor binding [inference]

DNA-binding transcription factor binding [inference]

RNA polymerase II-specific DNA-binding transcription factor binding [inference]

STAT family protein binding

enzyme binding [inference]

kinase binding [inference]

protein kinase binding [inference]

protein tyrosine kinase binding

protein dimerization activity [inference]

protein heterodimerization activity

SOCS family protein binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

cytokine receptor activity

immune receptor activity [inference]

cytokine receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Uncharacterized protein

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
J: Translation, ribosomal structure and biogenesis

Displaying **all 3** entries
InterPro
Fibronectin type III superfamily
Fibronectin type III
Immunoglobulin-like fold

Alliance of Genome Resources

Expression

Displaying **all 3** entries
Location	References
nucleus	PMID:12586061
membrane	FB:FBrf0231198
apical plasma membrane	PMID:12403714 PMID:18424141

Disease

Disease Ontology

Displaying **all 3** entries
DO ID	Disease Name	Source
DOID:0080269	autosomal dominant nonsyndromic deafness 73	Alliance of Genome Resources
DOID:0110529	autosomal recessive nonsyndromic deafness 84A	Alliance of Genome Resources
DOID:934	viral infectious disease	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 41 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources
Homo sapiens	23628		HGNC:9679
Mus musculus	237523		MGI:1096349
Rattus norvegicus	360417		RGD:620779
Danio rerio	555426		ZFIN:ZDB-GENE-050419-183
Drosophila pseudoobscura	4814949	7237_1:003557
Drosophila ananassae	6502981	7217_1:00327b
Drosophila yakuba	6525150	7245_1:000063
Drosophila erecta	6550496	7220_1:002fce
Drosophila grimshawi	6564859	7222_1:00000a
Drosophila mojavensis	6585956	7230_1:000284

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements