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interferon lambda 2

Summary

Gene Symbol

Ifnl2

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

330496

PubChem

330496

Alliance of Genome Resources

MGI:3647279

Annotation

Keyword

Antiviral defense
Cytokine
Glycoprotein
Reference proteome
Secreted
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
Q4VK74	Interleukin-28A

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
mucosal immune response	IDA	21518880
receptor signaling pathway via JAK-STAT	IEA
innate immune response	IBA
positive regulation of immune response	IEA
defense response to virus	IDA	21518880

GO Hierarchy

biological process

immune system process [inference]

immune response [inference]

organ or tissue specific immune response [inference]

mucosal immune response

innate immune response

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

receptor signaling pathway via STAT [inference]

receptor signaling pathway via JAK-STAT

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to virus [inference]

defense response to virus

defense response to other organism [inference]

innate immune response

defense response to symbiont [inference]

defense response to virus

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to other organism [inference]

innate immune response

defense response to symbiont [inference]

defense response to virus

immune response [inference]

organ or tissue specific immune response [inference]

mucosal immune response

innate immune response

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to virus [inference]

defense response to virus

defense response to other organism [inference]

innate immune response

defense response to symbiont [inference]

defense response to virus

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to virus [inference]

defense response to virus

defense response to other organism [inference]

innate immune response

defense response to symbiont [inference]

defense response to virus

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

positive regulation of immune system process [inference]

positive regulation of immune response

regulation of immune response [inference]

positive regulation of immune response

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of immune response

positive regulation of response to stimulus [inference]

positive regulation of immune response

regulation of response to stimulus [inference]

positive regulation of response to stimulus [inference]

positive regulation of immune response

regulation of immune response [inference]

positive regulation of immune response

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

receptor signaling pathway via STAT [inference]

receptor signaling pathway via JAK-STAT

Displaying **all 4** entries
GO Term	Evidence Code	PMID
extracellular region	ISO
extracellular space	IBA
extracellular space	IEA
interleukin-28 receptor complex	ISO

GO Hierarchy

cellular component

protein-containing complex [inference]

receptor complex [inference]

plasma membrane signaling receptor complex [inference]

interleukin-28 receptor complex

membrane protein complex [inference]

plasma membrane protein complex [inference]

plasma membrane signaling receptor complex [inference]

interleukin-28 receptor complex

cellular anatomical entity [inference]

Displaying **all 4** entries
GO Term	Evidence Code	PMID
signaling receptor binding	ISO
signaling receptor binding	IBA
cytokine activity	IEA
interleukin-28 receptor binding	ISO

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding

cytokine receptor binding [inference]

interleukin-28 receptor binding

receptor ligand activity [inference]

cytokine activity

molecular function regulator activity [inference]

signaling receptor regulator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

cytokine activity

molecular function activator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

cytokine activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Interferon lambda

Functional Category

K: Transcription
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
cytokine activity
defense response to virus
positive regulation of immune response
receptor signaling pathway via JAK-STAT
signaling receptor binding

Displaying **all 2** entries
InterPro
Interferon lambda superfamily
Interferon lambda

Ortholog

Displaying entries **1 - 10** of 78 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	282616		HUMAN43361
Homo sapiens	282617		HUMAN43355
Homo sapiens	282618	HGNC:18363	HUMAN43362
Xenopus tropicalis	330496	Xenbase:XB-GENE-855697
Canis lupus familiaris	611377		CANLF09644
Canis lupus familiaris	612539		CANLF01089
Rattus norvegicus	685840		RATNO17018
Felis catus	692347		FELCA06581
Macaca mulatta	695997		MACMU18875
Macaca mulatta	696117		MACMU18896

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements