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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
acyl-CoA dehydrogenase long chain
Summary
- Gene Symbol
-
- ACADL
- Aliases
-
- ACAD4
- LCAD
- long-chain acyl-CoA dehydrogenase
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Acetylation
- FAD
- Fatty acid metabolism
- Mitochondrion
- Oxidoreductase
- Phosphoprotein
- Reference proteome
- Transit peptide
- Proteins
| UniProt | Protein Name |
|---|---|
| P28330 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| long-chain fatty acid catabolic process | ||
| temperature homeostasis | ||
| positive regulation of cold-induced thermogenesis | ||
| negative regulation of fatty acid oxidation | ||
| regulation of cholesterol metabolic process |
GO Hierarchy
biological process
metabolic process [inference]
cellular process [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
negative regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of small molecule metabolic process [inference]
negative regulation of biological process [inference]
regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| cytoplasm | ||
| mitochondrial membrane | ||
| mitochondrial matrix |
|
|
| mitochondrion |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| fatty-acyl-CoA binding | ||
| long-chain-acyl-CoA dehydrogenase activity | ||
| flavin adenine dinucleotide binding | ||
| protein binding | ||
| palmitoyl-CoA oxidase activity |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
KEGG BRITE Database
Rhea
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:3748 | esophagus squamous cell carcinoma | |
| DOID:4766 | embryoma | |
| DOID:631 | fibromyalgia | |
| DOID:633 | myositis | |
| DOID:684 | hepatocellular carcinoma | |
| DOID:686 | liver carcinoma | |
| DOID:784 | chronic kidney disease | |
| DOID:9267 | urea cycle disorder | |
| DOID:9452 | steatotic liver disease | |
| DOID:9993 | hypoglycemia |
LIPID MAPS Gene / Proteome Database
- LMPD ID
- LMP000072
- Gene Name
- acyl-CoA dehydrogenase, long chain
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 36242 | FB:FBgn0086712 | ||
| 100180056 | CIOIN11529 | ||
| 102362263 | LATCH05938 | ||
| 394156 | ZFIN:ZDB-GENE-040426-771 | DANRE13576 | |
| 124627118 | ICTPU28947 | ||
| 115179855 | SALTR05811 | ||
| 115547731 | GADMO53010 | ||
| 101159651 | ORYLA08621 | ||
| 100698696 | ORENI43505 | ||
| 115577180 | SPAAU66091 |
