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MIRAGE
stimulator of interferon response cGAMP interactor 1
Summary
- Gene Symbol
-
- STING1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Autophagy
- Cell membrane
- Cytoplasm
- Cytoplasmic vesicle
- Disease variant
- Endoplasmic reticulum
- Golgi apparatus
- Host-virus interaction
- Innate immunity
- Ion channel
- Isopeptide bond
- Mitochondrion outer membrane
- Nucleotide-binding
- Palmitate
- Phosphoprotein
- Proteomics identification
- Reference proteome
- Signal
- Transmembrane helix
- Ubl conjugation
- Proteins
| UniProt | Protein Name |
|---|---|
| Q86WV6 |
|
| A0A494C0W5 |
|
| J3QTB1 |
|
| V5V0K2 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| autophagosome assembly | ||
| autophagosome assembly | ||
| activation of innate immune response | ||
| activation of innate immune response | ||
| activation of innate immune response |
GO Hierarchy
biological process
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of primary metabolic process [inference]
positive regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
regulation of cellular metabolic process [inference]
positive regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| Golgi membrane | ||
| autophagosome membrane | ||
| nucleoplasm | ||
| mitochondrial outer membrane | ||
| endosome |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| proton channel activity | ||
| protein kinase binding | ||
| protein kinase binding | ||
| ubiquitin protein ligase binding |
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Stimulator of interferon genes protein
- Functional Category
-
- E: Amino acid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| autophagosome assembly |
| cyclic-di-GMP binding |
| defense response to virus |
| nucleotide binding |
| positive regulation of macroautophagy |
| positive regulation of type I interferon production |
| InterPro |
|---|
| Stimulator of interferon genes protein, C-terminal domain superfamily |
| Stimulator of interferon genes protein |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0111457 | STING-associated vasculopathy with onset in infancy |
