Submissions
GlyTouCan
Glycan Structure Repository
GlyComb
Glycoconjugate Repository
GlycoPOST
Glycomics MS raw data Repository
UniCarb-DR
Glycomics MS Repository for glycan annotations from GlycoWorkbench
LM-GlycoRepo
Repository for lectin-assisted multimodality data
All Resources
Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / OrganismsTools
SugarDrawer
GlycanBuilder
Glycan Converters
GlycoMaple
GlycomeAtlas
LM-GlycomeAtlas
GALAXY
MCAW
GlycoSim
GRable
Guidelines
MIRAGE
insulin like growth factor 1 receptor
Summary
- Gene Symbol
-
- IGF1R
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Cell membrane
- Cleavage on pair of basic residues
- Direct protein sequencing
- Disease variant
- Disulfide bond
- Glycoprotein
- Host-virus interaction
- Isopeptide bond
- Phosphoprotein
- Proteomics identification
- Receptor
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Tyrosine-protein kinase
- Ubl conjugation
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| positive regulation of cell population proliferation | ||
| insulin receptor signaling pathway | ||
| insulin receptor signaling pathway | ||
| fibroblast growth factor receptor signaling pathway | ||
| negative regulation of muscle cell apoptotic process |
GO Hierarchy
- insulin receptor signaling pathway
- fibroblast growth factor receptor signaling pathway
- brain-derived neurotrophic factor receptor signaling pathway
- collagen-activated tyrosine kinase receptor signaling pathway
- vascular endothelial growth factor signaling pathway
- Kit signaling pathway
- insulin-like growth factor receptor signaling pathway
- hepatocyte growth factor receptor signaling pathway
- ephrin receptor signaling pathway
- immune response
- response to nicotine
- insulin receptor signaling pathway
- fibroblast growth factor receptor signaling pathway
- brain-derived neurotrophic factor receptor signaling pathway
- collagen-activated tyrosine kinase receptor signaling pathway
- vascular endothelial growth factor signaling pathway
- Kit signaling pathway
- insulin-like growth factor receptor signaling pathway
- hepatocyte growth factor receptor signaling pathway
- ephrin receptor signaling pathway
biological process
metabolic process [inference]
cellular process [inference]
signal transduction
cell surface receptor signaling pathway [inference]
enzyme-linked receptor protein signaling pathway [inference]
transmembrane receptor protein tyrosine kinase signaling pathway [inference]
cellular response to stimulus [inference]
cellular response to chemical stimulus [inference]
cellular response to organic substance [inference]
cellular response to hormone stimulus [inference]
cellular response to lipid [inference]
cellular response to organic cyclic compound [inference]
response to stimulus [inference]
response to endogenous stimulus [inference]
response to chemical [inference]
response to organic substance [inference]
response to hormone [inference]
response to organonitrogen compound [inference]
response to organic cyclic compound [inference]
response to lipid [inference]
cellular response to organic substance [inference]
cellular response to hormone stimulus [inference]
cellular response to lipid [inference]
cellular response to organic cyclic compound [inference]
cellular response to chemical stimulus [inference]
cellular response to organic substance [inference]
cellular response to hormone stimulus [inference]
cellular response to lipid [inference]
cellular response to organic cyclic compound [inference]
response to nitrogen compound [inference]
response to oxygen-containing compound [inference]
cellular response to stimulus [inference]
cellular response to chemical stimulus [inference]
cellular response to organic substance [inference]
cellular response to hormone stimulus [inference]
cellular response to lipid [inference]
cellular response to organic cyclic compound [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of signaling [inference]
positive regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
signal transduction
cell surface receptor signaling pathway [inference]
enzyme-linked receptor protein signaling pathway [inference]
transmembrane receptor protein tyrosine kinase signaling pathway [inference]
regulation of cell communication [inference]
regulation of cellular metabolic process [inference]
regulation of programmed cell death [inference]
positive regulation of cellular process [inference]
regulation of cellular component organization [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| nucleolus | ||
| plasma membrane | ||
| plasma membrane | ||
| plasma membrane | ||
| plasma membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| G-protein alpha-subunit binding | ||
| protein tyrosine kinase activity | ||
| protein tyrosine kinase activity | ||
| protein tyrosine kinase activity | ||
| GPI-linked ephrin receptor activity |
GO Hierarchy
- epidermal growth factor receptor activity
- fibroblast growth factor receptor activity
- hepatocyte growth factor receptor activity
- insulin receptor activity
- insulin-like growth factor receptor activity
- macrophage colony-stimulating factor receptor activity
- stem cell factor receptor activity
- vascular endothelial growth factor receptor activity
- boss receptor activity
- placental growth factor receptor activity
- protein tyrosine kinase collagen receptor activity
- brain-derived neurotrophic factor receptor activity
- epidermal growth factor receptor activity
- fibroblast growth factor receptor activity
- hepatocyte growth factor receptor activity
- insulin receptor activity
- insulin-like growth factor receptor activity
- macrophage colony-stimulating factor receptor activity
- stem cell factor receptor activity
- vascular endothelial growth factor receptor activity
- boss receptor activity
- placental growth factor receptor activity
- protein tyrosine kinase collagen receptor activity
- brain-derived neurotrophic factor receptor activity
- epidermal growth factor receptor activity
- fibroblast growth factor receptor activity
- hepatocyte growth factor receptor activity
- insulin receptor activity
- insulin-like growth factor receptor activity
- macrophage colony-stimulating factor receptor activity
- stem cell factor receptor activity
- vascular endothelial growth factor receptor activity
- boss receptor activity
- placental growth factor receptor activity
- protein tyrosine kinase collagen receptor activity
- brain-derived neurotrophic factor receptor activity
- epidermal growth factor receptor activity
- fibroblast growth factor receptor activity
- hepatocyte growth factor receptor activity
- insulin receptor activity
- insulin-like growth factor receptor activity
- macrophage colony-stimulating factor receptor activity
- stem cell factor receptor activity
- vascular endothelial growth factor receptor activity
- boss receptor activity
- placental growth factor receptor activity
- protein tyrosine kinase collagen receptor activity
- brain-derived neurotrophic factor receptor activity
- epidermal growth factor receptor activity
- fibroblast growth factor receptor activity
- hepatocyte growth factor receptor activity
- insulin receptor activity
- insulin-like growth factor receptor activity
- macrophage colony-stimulating factor receptor activity
- stem cell factor receptor activity
- vascular endothelial growth factor receptor activity
- boss receptor activity
- placental growth factor receptor activity
- protein tyrosine kinase collagen receptor activity
- brain-derived neurotrophic factor receptor activity
- epidermal growth factor receptor activity
- fibroblast growth factor receptor activity
- hepatocyte growth factor receptor activity
- insulin receptor activity
- insulin-like growth factor receptor activity
- macrophage colony-stimulating factor receptor activity
- stem cell factor receptor activity
- vascular endothelial growth factor receptor activity
- boss receptor activity
- placental growth factor receptor activity
- protein tyrosine kinase collagen receptor activity
- brain-derived neurotrophic factor receptor activity
- structural molecule activity
- epidermal growth factor receptor activity
- fibroblast growth factor receptor activity
- hepatocyte growth factor receptor activity
- insulin receptor activity
- insulin-like growth factor receptor activity
- macrophage colony-stimulating factor receptor activity
- stem cell factor receptor activity
- vascular endothelial growth factor receptor activity
- boss receptor activity
- placental growth factor receptor activity
- protein tyrosine kinase collagen receptor activity
- brain-derived neurotrophic factor receptor activity
molecular function
catalytic activity [inference]
transferase activity [inference]
transferase activity, transferring phosphorus-containing groups [inference]
kinase activity [inference]
protein kinase activity [inference]
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity [inference]
transmembrane receptor protein kinase activity [inference]
transmembrane receptor protein tyrosine kinase activity [inference]
phosphotransferase activity, alcohol group as acceptor [inference]
protein kinase activity [inference]
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity [inference]
transmembrane receptor protein kinase activity [inference]
transmembrane receptor protein tyrosine kinase activity [inference]
catalytic activity, acting on a protein [inference]
protein kinase activity [inference]
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity [inference]
transmembrane receptor protein kinase activity [inference]
transmembrane receptor protein tyrosine kinase activity [inference]
binding [inference]
molecular transducer activity [inference]
signaling receptor activity [inference]
transmembrane signaling receptor activity [inference]
transmembrane receptor protein kinase activity [inference]
transmembrane receptor protein tyrosine kinase activity [inference]
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- insulin receptor a
- Functional Category
-
- E: Amino acid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 105594004 | CERAT18055 | ||
| 105707635 | AOTNA11142 | ||
| 105809892 | PROCO03734 | ||
| 106573762 | SALSA47015 | ||
| 106836604 | EQUAS12857 | ||
| 107594738 | SINGR52076 | ||
| 107596941 | SINGR32147 | ||
| 108271091 | ICTPU01120 | ||
| 108538668 | RHIBE28551 | ||
| 109079742 | CYPCA11128 |
