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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
acyl-CoA dehydrogenase medium chain
Summary
- Gene Symbol
-
- ACADM
- Aliases
-
- ACAD1
- MCAD
- MCADH
- medium-chain acyl-CoA dehydrogenase
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Alternative splicing
- Direct protein sequencing
- Disease variant
- FAD
- Fatty acid metabolism
- Mitochondrion
- Oxidoreductase
- Phosphoprotein
- Proteomics identification
- Reference proteome
- Transit peptide
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| medium-chain fatty acid metabolic process | ||
| response to cold | ||
| carnitine biosynthetic process | ||
| regulation of gluconeogenesis | ||
| fatty acid beta-oxidation |
GO Hierarchy
biological process
metabolic process [inference]
cellular process [inference]
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| flavin adenine dinucleotide binding | ||
| medium-chain-acyl-CoA dehydrogenase activity | ||
| acyl-CoA dehydrogenase activity | ||
| identical protein binding |
GO Hierarchy
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
KEGG BRITE Database
Rhea
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:9008 | psoriatic arthritis | |
| DOID:9256 | colorectal cancer | |
| DOID:9266 | cystinuria | |
| DOID:9267 | urea cycle disorder | |
| DOID:9281 | phenylketonuria | |
| DOID:9452 | steatotic liver disease | |
| DOID:9870 | galactosemia | |
| DOID:9970 | obesity | |
| DOID:9993 | hypoglycemia |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0001315 | Reduced tendon reflexes |
| HP:0001397 | Hepatic steatosis |
| HP:0001410 | Decreased liver function |
| HP:0001640 | Cardiomegaly |
| HP:0001942 | Metabolic acidosis |
| HP:0001943 | Hypoglycemia |
| HP:0001946 | Ketosis |
| HP:0001987 | Hyperammonemia |
| HP:0002013 | Vomiting |
| HP:0002014 | Diarrhea |
| Disease ID | Disease Name |
|---|---|
| OMIM:201450 |
|
| ORPHA:42 |
|
PubChem Disease
- GHR Health Conditions
- MedGen Diseases
- OMIM Phenotypes
- KEGG Diseases
LIPID MAPS Gene / Proteome Database
- LMPD ID
- LMP000167
- Gene Name
- acyl-CoA dehydrogenase, C-4 to C-12 straight chain
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 173979 | WB:WBGene00019406 | ||
| 181758 | WB:WBGene00020812 | ||
| 24104866 | WB:WBGene00020366 | ||
| 38864 | FB:FBgn0035811 | ||
| 103174736 | CALMI06023 | ||
| 102354536 | LATCH07272 | ||
| 102354968 | LATCH07272 | ||
| 406283 | ZFIN:ZDB-GENE-040426-1945 | DANRE28378 | |
| 103046142 | ASTMX03172 | ||
| 108278040 | ICTPU09639 |
