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inhibitor of nuclear factor kappa B kinase subunit beta

Summary

Gene Symbol

IKBKB

Organism

Homo sapiens (human)

External Links

NCBI Gene

3551

PubChem

3551

Alliance of Genome Resources

HGNC:5960

Annotation

Keyword

3D-structure
ATP-binding
Acetylation
Alternative splicing
Cytoplasm
Direct protein sequencing
Disease variant
Host-virus interaction
Hydroxylation
Isopeptide bond
Membrane
Nucleus
Phosphoprotein
Reference proteome
S-nitrosylation
SCID
Serine/threonine-protein kinase
Ubl conjugation

Proteins

Displaying 1 entry
UniProt	Protein Name
O14920	I-kappa-B kinase 2 Nuclear factor NF-kappa-B inhibitor kinase beta Serine/threonine protein kinase IKBKB

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 33 in total

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GO Term	Evidence Code	PMID
toll-like receptor 3 signaling pathway	TAS
interleukin-1-mediated signaling pathway	IMP TAS	25816133
T cell receptor signaling pathway	TAS
regulation of toll-like receptor signaling pathway
regulation of phosphorylation	IDA	26212789

GO Hierarchy

biological process

immune system process [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 3 signaling pathway

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

antigen receptor-mediated signaling pathway [inference]

T cell receptor signaling pathway

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 3 signaling pathway

immune response [inference]

innate immune response

antigen processing and presentation [inference]

antigen processing and presentation of exogenous antigen [inference]

antigen processing and presentation of exogenous peptide antigen [inference]

antigen processing and presentation of exogenous peptide antigen via MHC class I [inference]

antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent

antigen processing and presentation of peptide antigen [inference]

antigen processing and presentation of peptide antigen via MHC class I [inference]

antigen processing and presentation of exogenous peptide antigen via MHC class I [inference]

antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent

antigen processing and presentation of exogenous peptide antigen [inference]

antigen processing and presentation of exogenous peptide antigen via MHC class I [inference]

antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

peptidyl-amino acid modification [inference]

peptidyl-serine modification [inference]

peptidyl-serine phosphorylation

protein maturation

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

protein phosphorylation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

peptidyl-amino acid modification [inference]

peptidyl-serine modification [inference]

peptidyl-serine phosphorylation

protein maturation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

peptidyl-amino acid modification [inference]

peptidyl-serine modification [inference]

peptidyl-serine phosphorylation

protein maturation

macromolecule modification [inference]

protein modification process [inference]

protein phosphorylation

peptidyl-amino acid modification [inference]

peptidyl-serine modification [inference]

peptidyl-serine phosphorylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

peptidyl-amino acid modification [inference]

peptidyl-serine modification [inference]

peptidyl-serine phosphorylation

protein maturation

cellular process [inference]

signal transduction [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

antigen receptor-mediated signaling pathway [inference]

T cell receptor signaling pathway

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 3 signaling pathway

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

antigen receptor-mediated signaling pathway [inference]

T cell receptor signaling pathway

Fc receptor signaling pathway [inference]

Fc-epsilon receptor signaling pathway

cell surface receptor signaling pathway [inference]

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

antigen receptor-mediated signaling pathway [inference]

T cell receptor signaling pathway

Fc receptor signaling pathway [inference]

Fc-epsilon receptor signaling pathway

cytokine-mediated signaling pathway [inference]

intracellular receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 3 signaling pathway

intracellular signal transduction [inference]

MAPK cascade [inference]

stress-activated MAPK cascade

canonical NF-kappaB signal transduction

stress-activated protein kinase signaling cascade [inference]

stress-activated MAPK cascade

actin filament-based process [inference]

actin cytoskeleton organization [inference]

cortical actin cytoskeleton organization

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

protein phosphorylation

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

protein localization to cell periphery [inference]

protein localization to plasma membrane

cellular response to stimulus [inference]

cellular response to stress [inference]

stress-activated protein kinase signaling cascade [inference]

stress-activated MAPK cascade

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to tumor necrosis factor

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

actin cytoskeleton organization [inference]

cortical actin cytoskeleton organization

cortical cytoskeleton organization [inference]

cortical actin cytoskeleton organization

protein-containing complex organization [inference]

protein-DNA complex organization [inference]

chromatin organization [inference]

chromatin remodeling

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to virus

defense response to other organism [inference]

innate immune response

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response

defense response to other organism [inference]

innate immune response

cellular response to stress [inference]

stress-activated protein kinase signaling cascade [inference]

stress-activated MAPK cascade

immune response [inference]

innate immune response

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to virus

defense response to other organism [inference]

innate immune response

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to virus

defense response to other organism [inference]

innate immune response

response to lectin [inference]

cellular response to lectin [inference]

stimulatory C-type lectin receptor signaling pathway

response to chemical [inference]

response to organic substance [inference]

response to cytokine [inference]

response to tumor necrosis factor [inference]

cellular response to tumor necrosis factor

cellular response to cytokine stimulus [inference]

cellular response to tumor necrosis factor

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to tumor necrosis factor

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to tumor necrosis factor

cellular response to stimulus [inference]

cellular response to stress [inference]

stress-activated protein kinase signaling cascade [inference]

stress-activated MAPK cascade

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to tumor necrosis factor

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

protein localization to cell periphery [inference]

protein localization to plasma membrane

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

protein localization to cell periphery [inference]

protein localization to plasma membrane

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

positive regulation of immune system process [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 3 signaling pathway

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

antigen receptor-mediated signaling pathway [inference]

T cell receptor signaling pathway

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 3 signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 3 signaling pathway

regulation of immune response [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

antigen receptor-mediated signaling pathway [inference]

T cell receptor signaling pathway

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 3 signaling pathway

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

antigen receptor-mediated signaling pathway [inference]

T cell receptor signaling pathway

Fc receptor signaling pathway [inference]

Fc-epsilon receptor signaling pathway

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 3 signaling pathway

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor signaling pathway

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 3 signaling pathway

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

antigen receptor-mediated signaling pathway [inference]

T cell receptor signaling pathway

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 3 signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 3 signaling pathway

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of myosin-light-chain-phosphatase activity

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of dephosphorylation [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of myosin-light-chain-phosphatase activity

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of myosin-light-chain-phosphatase activity

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of myosin-light-chain-phosphatase activity

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of dephosphorylation [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of myosin-light-chain-phosphatase activity

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of myosin-light-chain-phosphatase activity

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of phosphorus metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of dephosphorylation [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of myosin-light-chain-phosphatase activity

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of myosin-light-chain-phosphatase activity

regulation of phosphate metabolic process [inference]

regulation of dephosphorylation [inference]

regulation of phosphatase activity [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of myosin-light-chain-phosphatase activity

regulation of phosphoprotein phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of myosin-light-chain-phosphatase activity

regulation of myosin-light-chain-phosphatase activity [inference]

negative regulation of myosin-light-chain-phosphatase activity

regulation of protein dephosphorylation [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of myosin-light-chain-phosphatase activity

regulation of phosphoprotein phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of myosin-light-chain-phosphatase activity

regulation of myosin-light-chain-phosphatase activity [inference]

negative regulation of myosin-light-chain-phosphatase activity

negative regulation of dephosphorylation [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of myosin-light-chain-phosphatase activity

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of myosin-light-chain-phosphatase activity

regulation of phosphorylation

negative regulation of phosphate metabolic process [inference]

negative regulation of dephosphorylation [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of myosin-light-chain-phosphatase activity

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of myosin-light-chain-phosphatase activity

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of myosin-light-chain-phosphatase activity

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of myosin-light-chain-phosphatase activity

regulation of protein dephosphorylation [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of myosin-light-chain-phosphatase activity

regulation of phosphoprotein phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of myosin-light-chain-phosphatase activity

regulation of myosin-light-chain-phosphatase activity [inference]

negative regulation of myosin-light-chain-phosphatase activity

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of myosin-light-chain-phosphatase activity

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of myosin-light-chain-phosphatase activity

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of myosin-light-chain-phosphatase activity

regulation of protein dephosphorylation [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of myosin-light-chain-phosphatase activity

regulation of phosphoprotein phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of myosin-light-chain-phosphatase activity

regulation of myosin-light-chain-phosphatase activity [inference]

negative regulation of myosin-light-chain-phosphatase activity

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of myosin-light-chain-phosphatase activity

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of myosin-light-chain-phosphatase activity

regulation of protein dephosphorylation [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of myosin-light-chain-phosphatase activity

regulation of phosphoprotein phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of myosin-light-chain-phosphatase activity

regulation of myosin-light-chain-phosphatase activity [inference]

negative regulation of myosin-light-chain-phosphatase activity

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of myosin-light-chain-phosphatase activity

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of cytokine-mediated signaling pathway [inference]

regulation of tumor necrosis factor-mediated signaling pathway

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor signaling pathway

regulation of intracellular signal transduction [inference]

regulation of canonical NF-kappaB signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 3 signaling pathway

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

antigen receptor-mediated signaling pathway [inference]

T cell receptor signaling pathway

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 3 signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 3 signaling pathway

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of response to stimulus [inference]

positive regulation of response to biotic stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 3 signaling pathway

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of defense response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 3 signaling pathway

positive regulation of response to external stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 3 signaling pathway

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 3 signaling pathway

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

antigen receptor-mediated signaling pathway [inference]

T cell receptor signaling pathway

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 3 signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 3 signaling pathway

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of myosin-light-chain-phosphatase activity

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of dephosphorylation [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of myosin-light-chain-phosphatase activity

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of myosin-light-chain-phosphatase activity

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of myosin-light-chain-phosphatase activity

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of dephosphorylation [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of myosin-light-chain-phosphatase activity

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of myosin-light-chain-phosphatase activity

negative regulation of cellular component organization [inference]

negative regulation of cell junction assembly [inference]

negative regulation of bicellular tight junction assembly

regulation of response to stimulus [inference]

regulation of response to biotic stimulus [inference]

positive regulation of response to biotic stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 3 signaling pathway

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 3 signaling pathway

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor signaling pathway

regulation of signal transduction [inference]

regulation of cytokine-mediated signaling pathway [inference]

regulation of tumor necrosis factor-mediated signaling pathway

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor signaling pathway

regulation of intracellular signal transduction [inference]

regulation of canonical NF-kappaB signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

regulation of response to external stimulus [inference]

positive regulation of response to external stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 3 signaling pathway

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 3 signaling pathway

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor signaling pathway

positive regulation of response to stimulus [inference]

positive regulation of response to biotic stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 3 signaling pathway

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of defense response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 3 signaling pathway

positive regulation of response to external stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 3 signaling pathway

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 3 signaling pathway

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

antigen receptor-mediated signaling pathway [inference]

T cell receptor signaling pathway

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 3 signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 3 signaling pathway

regulation of immune response [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

antigen receptor-mediated signaling pathway [inference]

T cell receptor signaling pathway

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 3 signaling pathway

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

antigen receptor-mediated signaling pathway [inference]

T cell receptor signaling pathway

Fc receptor signaling pathway [inference]

Fc-epsilon receptor signaling pathway

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 3 signaling pathway

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor signaling pathway

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 3 signaling pathway

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

antigen receptor-mediated signaling pathway [inference]

T cell receptor signaling pathway

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 3 signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 3 signaling pathway

regulation of response to cytokine stimulus [inference]

regulation of cytokine-mediated signaling pathway [inference]

regulation of tumor necrosis factor-mediated signaling pathway

regulation of response to stress [inference]

regulation of defense response [inference]

positive regulation of defense response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 3 signaling pathway

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 3 signaling pathway

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor signaling pathway

regulation of developmental process [inference]

regulation of cell differentiation [inference]

regulation of epithelial cell differentiation [inference]

regulation of endothelial cell differentiation [inference]

regulation of endothelial cell development [inference]

regulation of establishment of endothelial barrier

regulation of cell development [inference]

regulation of endothelial cell development [inference]

regulation of establishment of endothelial barrier

regulation of multicellular organismal development [inference]

regulation of epithelial cell differentiation [inference]

regulation of endothelial cell differentiation [inference]

regulation of endothelial cell development [inference]

regulation of establishment of endothelial barrier

regulation of cellular process [inference]

signal transduction [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

antigen receptor-mediated signaling pathway [inference]

T cell receptor signaling pathway

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 3 signaling pathway

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

antigen receptor-mediated signaling pathway [inference]

T cell receptor signaling pathway

Fc receptor signaling pathway [inference]

Fc-epsilon receptor signaling pathway

cell surface receptor signaling pathway [inference]

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

antigen receptor-mediated signaling pathway [inference]

T cell receptor signaling pathway

Fc receptor signaling pathway [inference]

Fc-epsilon receptor signaling pathway

cytokine-mediated signaling pathway [inference]

intracellular receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

toll-like receptor 3 signaling pathway

intracellular signal transduction [inference]

MAPK cascade [inference]

stress-activated MAPK cascade

canonical NF-kappaB signal transduction

stress-activated protein kinase signaling cascade [inference]

stress-activated MAPK cascade

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of cytokine-mediated signaling pathway [inference]

regulation of tumor necrosis factor-mediated signaling pathway

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor signaling pathway

regulation of intracellular signal transduction [inference]

regulation of canonical NF-kappaB signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of dephosphorylation [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of myosin-light-chain-phosphatase activity

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of myosin-light-chain-phosphatase activity

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of phosphorus metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of dephosphorylation [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of myosin-light-chain-phosphatase activity

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of myosin-light-chain-phosphatase activity

regulation of phosphate metabolic process [inference]

regulation of dephosphorylation [inference]

regulation of phosphatase activity [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of myosin-light-chain-phosphatase activity

regulation of phosphoprotein phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of myosin-light-chain-phosphatase activity

regulation of myosin-light-chain-phosphatase activity [inference]

negative regulation of myosin-light-chain-phosphatase activity

regulation of protein dephosphorylation [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of myosin-light-chain-phosphatase activity

regulation of phosphoprotein phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of myosin-light-chain-phosphatase activity

regulation of myosin-light-chain-phosphatase activity [inference]

negative regulation of myosin-light-chain-phosphatase activity

negative regulation of dephosphorylation [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of myosin-light-chain-phosphatase activity

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of myosin-light-chain-phosphatase activity

regulation of phosphorylation

negative regulation of phosphate metabolic process [inference]

negative regulation of dephosphorylation [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of myosin-light-chain-phosphatase activity

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of myosin-light-chain-phosphatase activity

regulation of cellular component biogenesis [inference]

regulation of cell junction assembly [inference]

negative regulation of cell junction assembly [inference]

negative regulation of bicellular tight junction assembly

regulation of bicellular tight junction assembly [inference]

negative regulation of bicellular tight junction assembly

regulation of cell differentiation [inference]

regulation of epithelial cell differentiation [inference]

regulation of endothelial cell differentiation [inference]

regulation of endothelial cell development [inference]

regulation of establishment of endothelial barrier

regulation of cell development [inference]

regulation of endothelial cell development [inference]

regulation of establishment of endothelial barrier

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of dephosphorylation [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of myosin-light-chain-phosphatase activity

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of myosin-light-chain-phosphatase activity

negative regulation of cellular component organization [inference]

negative regulation of cell junction assembly [inference]

negative regulation of bicellular tight junction assembly

regulation of cellular component organization [inference]

negative regulation of cellular component organization [inference]

negative regulation of cell junction assembly [inference]

negative regulation of bicellular tight junction assembly

regulation of cell junction assembly [inference]

negative regulation of cell junction assembly [inference]

negative regulation of bicellular tight junction assembly

regulation of bicellular tight junction assembly [inference]

negative regulation of bicellular tight junction assembly

regulation of multicellular organismal process [inference]

regulation of multicellular organismal development [inference]

regulation of epithelial cell differentiation [inference]

regulation of endothelial cell differentiation [inference]

regulation of endothelial cell development [inference]

regulation of establishment of endothelial barrier

regulation of molecular function [inference]

negative regulation of molecular function [inference]

negative regulation of catalytic activity [inference]

negative regulation of hydrolase activity [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of myosin-light-chain-phosphatase activity

positive regulation of molecular function [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

regulation of catalytic activity [inference]

negative regulation of catalytic activity [inference]

negative regulation of hydrolase activity [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of myosin-light-chain-phosphatase activity

regulation of hydrolase activity [inference]

regulation of phosphatase activity [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of myosin-light-chain-phosphatase activity

regulation of phosphoprotein phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of myosin-light-chain-phosphatase activity

regulation of myosin-light-chain-phosphatase activity [inference]

negative regulation of myosin-light-chain-phosphatase activity

negative regulation of hydrolase activity [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of myosin-light-chain-phosphatase activity

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

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GO Term	Evidence Code	PMID
IkappaB kinase complex	IBA IPI TAS	18626576 20434986
membrane raft	IEA
cytoplasmic side of plasma membrane	ISS
CD40 receptor complex	ISS
nucleus	IEA

GO Hierarchy

cellular component

protein-containing complex [inference]

receptor complex [inference]

plasma membrane signaling receptor complex [inference]

CD40 receptor complex

membrane protein complex [inference]

plasma membrane protein complex [inference]

plasma membrane signaling receptor complex [inference]

CD40 receptor complex

catalytic complex [inference]

transferase complex [inference]

transferase complex, transferring phosphorus-containing groups [inference]

protein kinase complex [inference]

serine/threonine protein kinase complex [inference]

IkappaB kinase complex

cellular anatomical entity [inference]

membrane [inference]

membrane microdomain [inference]

membrane raft

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

side of membrane [inference]

cytoplasmic side of membrane [inference]

cytoplasmic side of plasma membrane

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
protein binding	IPI	10521409 10733566 11297557 11971985 12482991 12486103 12656673 12842894 14743216 15084260 15389287 15601829 15749833 16126728 16129692 16286467 16319058 16365431 16938294 17363973 17568778 17693255 17939994 18198944 18266467 18462684 18930133 19196987 19345327 19365808 19666608 19675099 19706536 19883646 20098747 20211142 20368414 20434986 20600852 21399639 21423167 21474709 21765415 21903422 22037600 22810585 22904686 23091055 23104095 24618592 25036637 25241761 25326418 25759022 25852190 26212789 26334375 26496610 27426725 28514442 30561431 30833792 32209697 32707033 32814053 32935379 33895773 33961781 35271311 9520446 9751060
protein serine kinase activity	IEA
protein heterodimerization activity	IDA	23091055
protein serine/threonine kinase activity	EXP IBA IDA TAS	11297557 12656673 14673179 15084260 18692471 23613522 25326418 25636800 32209697
identical protein binding	IPI	16319058 21423167 23776406

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

protein kinase activity

protein serine/threonine kinase activity

histone kinase activity [inference]

histone H2A kinase activity [inference]

histone H2AS1 kinase activity

protein serine kinase activity

phosphotransferase activity, alcohol group as acceptor [inference]

protein kinase activity

protein serine/threonine kinase activity

histone kinase activity [inference]

histone H2A kinase activity [inference]

histone H2AS1 kinase activity

protein serine kinase activity

catalytic activity, acting on a protein [inference]

protein kinase activity

protein serine/threonine kinase activity

histone kinase activity [inference]

histone H2A kinase activity [inference]

histone H2AS1 kinase activity

protein serine kinase activity

histone modifying activity [inference]

histone kinase activity [inference]

histone H2A kinase activity [inference]

histone H2AS1 kinase activity

binding [inference]

protein binding

signaling receptor binding [inference]

transferrin receptor binding

enzyme binding [inference]

kinase binding [inference]

protein kinase binding

identical protein binding

protein homodimerization activity

protein dimerization activity [inference]

scaffold protein binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

inhibitor of nuclear factor kappa-B kinase subunit alpha

Functional Category

O: Posttranslational modification, protein turnover, chaperones
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 7** entries
Gene Ontology
ATP binding
IkappaB kinase activity
kinase activity
nucleotide binding
phosphorylation
transferase activity
tumor necrosis factor-mediated signaling pathway

Displaying **all 5** entries
InterPro
IKBKB, scaffold dimerization domain superfamily
IKBKB, scaffold dimerization domain
Protein kinase domain
Protein kinase-like domain superfamily
Serine/threonine-protein kinase, active site

Disease

Disease Ontology

Displaying entries **1 - 10** of 15 in total

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DO ID	Disease Name	Source
DOID:0060180	colitis	Alliance of Genome Resources
DOID:0111959	immunodeficiency 15B	Alliance of Genome Resources
DOID:0111960	immunodeficiency 15A	Alliance of Genome Resources
DOID:10283	prostate cancer	Alliance of Genome Resources
DOID:10652	Alzheimer's disease	Alliance of Genome Resources
DOID:10763	hypertension	Alliance of Genome Resources
DOID:1612	breast cancer	Alliance of Genome Resources
DOID:219	colon cancer	Alliance of Genome Resources
DOID:224	transient cerebral ischemia	Alliance of Genome Resources
DOID:2526	prostate adenocarcinoma	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 65 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Mus musculus	16150		MGI:1338071	MOUSE58559
Drosophila melanogaster	44432		FB:FBgn0024222
Rattus norvegicus	84351		RGD:621375	RATNO10999
Bos taurus	281854			BOVIN22161
Xenopus laevis	432200		Xenbase:XB-GENE-949882
Xenopus tropicalis	448125		Xenbase:XB-GENE-949877
Pan troglodytes	472749	9598_0:002641
Canis lupus familiaris	482839			CANLF04654
Danio rerio	563560		ZFIN:ZDB-GENE-071115-2	DANRE43216
Macaca mulatta	704683			MACMU43308

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements