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ALG11, alpha-1,2-mannosyltransferase

Summary

Gene Symbol

Alg11

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

361174

KEGG Gene ID

rno:361174

PubChem

361174

Alliance of Genome Resources

RGD:1564725

Annotation

Keyword

Endoplasmic reticulum
Glycosyltransferase
Reference proteome
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
D3ZCQ2
A6IW88

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
protein N-linked glycosylation	IBA ISO
dolichol-linked oligosaccharide biosynthetic process	IBA ISO

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

biosynthetic process [inference]

organic substance biosynthetic process [inference]

carbohydrate derivative biosynthetic process [inference]

oligosaccharide-lipid intermediate biosynthetic process [inference]

dolichol-linked oligosaccharide biosynthetic process

cellular metabolic process [inference]

cellular lipid metabolic process [inference]

oligosaccharide-lipid intermediate biosynthetic process [inference]

dolichol-linked oligosaccharide biosynthetic process

isoprenoid metabolic process [inference]

polyprenol metabolic process [inference]

dolichol metabolic process [inference]

dolichol-linked oligosaccharide biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

oligosaccharide-lipid intermediate biosynthetic process [inference]

dolichol-linked oligosaccharide biosynthetic process

isoprenoid metabolic process [inference]

polyprenol metabolic process [inference]

dolichol metabolic process [inference]

dolichol-linked oligosaccharide biosynthetic process

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

small molecule metabolic process [inference]

alcohol metabolic process [inference]

polyprenol metabolic process [inference]

dolichol metabolic process [inference]

dolichol-linked oligosaccharide biosynthetic process

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein N-linked glycosylation

organic substance metabolic process [inference]

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

oligosaccharide-lipid intermediate biosynthetic process [inference]

dolichol-linked oligosaccharide biosynthetic process

isoprenoid metabolic process [inference]

polyprenol metabolic process [inference]

dolichol metabolic process [inference]

dolichol-linked oligosaccharide biosynthetic process

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein N-linked glycosylation

carbohydrate derivative metabolic process [inference]

carbohydrate derivative biosynthetic process [inference]

oligosaccharide-lipid intermediate biosynthetic process [inference]

dolichol-linked oligosaccharide biosynthetic process

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

organic substance biosynthetic process [inference]

carbohydrate derivative biosynthetic process [inference]

oligosaccharide-lipid intermediate biosynthetic process [inference]

dolichol-linked oligosaccharide biosynthetic process

organic hydroxy compound metabolic process [inference]

alcohol metabolic process [inference]

polyprenol metabolic process [inference]

dolichol metabolic process [inference]

dolichol-linked oligosaccharide biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular lipid metabolic process [inference]

oligosaccharide-lipid intermediate biosynthetic process [inference]

dolichol-linked oligosaccharide biosynthetic process

isoprenoid metabolic process [inference]

polyprenol metabolic process [inference]

dolichol metabolic process [inference]

dolichol-linked oligosaccharide biosynthetic process

Displaying 1 entry
GO Term	Evidence Code	PMID
endoplasmic reticulum membrane	IBA ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

Displaying 1 entry
GO Term	Evidence Code	PMID
GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity	IBA ISO

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

hexosyltransferase activity [inference]

mannosyltransferase activity [inference]

alpha-1,2-mannosyltransferase activity [inference]

GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity

glycolipid mannosyltransferase activity [inference]

GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase

Functional Category

M: Cell wall/membrane/envelope biogenesis
P: Inorganic ion transport and metabolism
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
GDP-Man
oligosaccharide-lipid intermediate biosynthetic process
protein N-linked glycosylation
transferase activity

Displaying **all 3** entries
InterPro
ALG11 mannosyltransferase, N-terminal
ALG11 mannosyltransferase
Glycosyl transferase, family 1

KEGG BRITE Database

Orthology

K03844

Name

alpha-1,2-mannosyltransferase [EC:2.4.1.131]

References

11278778

Reactions

Displaying **all 2** entries
KEGG Reaction	Enzyme	Acceptor	Product
R06127	2.4.1.131	G43547MI	G35257SQ
R06128	2.4.1.131	G35257SQ	G59406KS

Rhea

GDP-α-D-mannose

H⁺ + GDP

Enzyme

2.4.1.131

PMID

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0080567	congenital disorder of glycosylation Ip	Alliance of Genome Resources

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP013428
Gene Name: ALG11, alpha-1,2-mannosyltransferase

Ortholog

Displaying entries **1 - 10** of **130** in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	40402		FB:FBgn0037108
Caenorhabditis elegans	176032		WB:WBGene00015162
Mus musculus	207958	10090_1:002aae	MGI:2142632	MOUSE58423
Xenopus tropicalis	394898		Xenbase:XB-GENE-5934131
Danio rerio	407614		ZFIN:ZDB-GENE-030131-7282	DANRE18152
Homo sapiens	440138		HGNC:32456	HUMAN17181
Pan troglodytes	452735			PANTR07826
Bos taurus	540845			BOVIN03731
Saccharomyces cerevisiae S288C	855679		SGD:S000004993
Monodelphis domestica	100028147			MONDO22477

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Last updated: December 9, 2024