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protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)

Summary

Gene Symbol

Pomgnt1

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

362567

KEGG Gene ID

rno:362567

PubChem

362567

Alliance of Genome Resources

RGD:1359396

Annotation

Keyword

Disulfide bond
Glycosyltransferase
Golgi apparatus
Lectin
Manganese
Metal-binding
Phosphoprotein
Reference proteome
Signal-anchor
Transmembrane helix

Proteins

Displaying **all 3** entries
UniProt	Protein Name
Q5XIN7
A0A8I6AMP8
A6JZ66

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 14 in total

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GO Term	Evidence Code	PMID
sensory perception of sound	IEA ISO
reactive gliosis	IEA ISO
biological_process	ND
myelination	IEA ISO
localization of cell	IEA ISO

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process

protein glycosylation

protein O-linked glycosylation

protein mannosylation [inference]

protein O-linked mannosylation

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process

protein glycosylation

protein O-linked glycosylation

protein mannosylation [inference]

protein O-linked mannosylation

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation

protein O-linked glycosylation

protein mannosylation [inference]

protein O-linked mannosylation

mannosylation [inference]

protein mannosylation [inference]

protein O-linked mannosylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

gene expression

protein metabolic process [inference]

protein modification process

protein glycosylation

protein O-linked glycosylation

protein mannosylation [inference]

protein O-linked mannosylation

macromolecule modification [inference]

protein modification process

protein glycosylation

protein O-linked glycosylation

protein mannosylation [inference]

protein O-linked mannosylation

macromolecule glycosylation [inference]

protein glycosylation

protein O-linked glycosylation

protein mannosylation [inference]

protein O-linked mannosylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process

protein glycosylation

protein O-linked glycosylation

protein mannosylation [inference]

protein O-linked mannosylation

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

cellular process [inference]

ensheathment of neurons [inference]

axon ensheathment [inference]

myelination

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

localization of cell

cellular component organization or biogenesis [inference]

cellular component organization [inference]

extracellular structure organization [inference]

extracellular matrix organization [inference]

basement membrane organization

external encapsulating structure organization [inference]

extracellular matrix organization [inference]

basement membrane organization

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

sensory perception [inference]

sensory perception of mechanical stimulus [inference]

sensory perception of sound

developmental process [inference]

anatomical structure development [inference]

dentate gyrus development

animal organ development [inference]

brain development

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response [inference]

neuroinflammatory response [inference]

reactive gliosis

localization [inference]

localization of cell

Displaying **all 2** entries
GO Term	Evidence Code	PMID
membrane	ISO ISS
Golgi membrane	IBA IEA ISO ISS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle membrane [inference]

bounding membrane of organelle [inference]

Golgi membrane

Displaying **all 5** entries
GO Term	Evidence Code	PMID
manganese ion binding	IEA ISO ISS
alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity	IEA
beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity	IBA IEA ISO
acetylglucosaminyltransferase activity	IEA ISO ISS
carbohydrate binding	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

UDP-glycosyltransferase activity [inference]

acetylglucosaminyltransferase activity

hexosyltransferase activity [inference]

acetylglucosaminyltransferase activity

catalytic activity, acting on a protein [inference]

catalytic activity, acting on a glycoprotein [inference]

binding [inference]

carbohydrate binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

manganese ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1

Functional Category

E: Amino acid transport and metabolism
F: Nucleotide transport and metabolism
T: Signal transduction mechanisms

Displaying **all 6** entries
Gene Ontology
O-glycan processing
acetylglucosaminyltransferase activity
beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity
manganese ion binding
metal ion binding
transferase activity

Displaying **all 4** entries
InterPro
Glycosyl transferase, family 13
ILEI/PANDER domain
Nucleotide-diphospho-sugar transferases
Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1, PANDER-like domain

KEGG BRITE Database

Orthology

K09666

Name

beta-1,2-N-acetylglucosaminyltransferase [EC:2.4.1.-]

References

11709191

Reactions

Displaying 1 entry
KEGG Reaction	Enzyme	Acceptor	Product
R07619	2.4.1.-	G61491DK	G85856KC

Disease

Disease Ontology

Displaying **all 8** entries
DO ID	Disease Name	Source
DOID:0050453	lissencephaly	Alliance of Genome Resources
DOID:0050560	Walker-Warburg syndrome	Alliance of Genome Resources
DOID:0050588	muscular dystrophy-dystroglycanopathy type B1	Alliance of Genome Resources
DOID:0110292	autosomal recessive limb-girdle muscular dystrophy type 2O	Alliance of Genome Resources
DOID:0111236	congenital muscular dystrophy-dystroglycanopathy type A3	Alliance of Genome Resources
DOID:0112378	muscular dystrophy-dystroglycanopathy type B3	Alliance of Genome Resources
DOID:10584	retinitis pigmentosa	Alliance of Genome Resources
DOID:9884	muscular dystrophy	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of **115** in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	55624		HGNC:19139	HUMAN49644
Mus musculus	68273	10090_1:001098	MGI:1915523	MOUSE40777
Pan troglodytes	456564			PANTR20974
Canis lupus familiaris	482511			CANLF04063
Bos taurus	506551			BOVIN27036
Danio rerio	571876		ZFIN:ZDB-GENE-070112-991	DANRE37989
Macaca mulatta	707205			MACMU25446
Sus scrofa	780413			PIGXX30490
Monodelphis domestica	100024121			MONDO10163
Xenopus tropicalis	100158594		Xenbase:XB-GENE-959856

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.1.0

Last updated: December 9, 2024