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protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)

Summary

Gene Symbol

Pomgnt1

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

362567

KEGG Gene ID

rno:362567

PubChem

362567

Alliance of Genome Resources

RGD:1359396

Annotation

Keyword

Disulfide bond
Glycosyltransferase
Golgi apparatus
Lectin
Manganese
Metal-binding
Phosphoprotein
Reference proteome
Signal-anchor
Transmembrane helix

Proteins

Displaying **all 3** entries
UniProt	Protein Name
Q5XIN7
A0A8I6AMP8
A6JZ66

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 14 in total

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GO Term	Evidence Code	PMID
myelination	IEA ISO
brain development	ISO
reactive gliosis	IEA ISO
protein O-linked glycosylation	ISO ISS
biological_process	ND

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process

protein glycosylation

protein O-linked glycosylation

protein mannosylation [inference]

protein O-linked mannosylation

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process

protein glycosylation

protein O-linked glycosylation

protein mannosylation [inference]

protein O-linked mannosylation

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation

protein O-linked glycosylation

protein mannosylation [inference]

protein O-linked mannosylation

mannosylation [inference]

protein mannosylation [inference]

protein O-linked mannosylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

gene expression

protein metabolic process [inference]

protein modification process

protein glycosylation

protein O-linked glycosylation

protein mannosylation [inference]

protein O-linked mannosylation

macromolecule modification [inference]

protein modification process

protein glycosylation

protein O-linked glycosylation

protein mannosylation [inference]

protein O-linked mannosylation

macromolecule glycosylation [inference]

protein glycosylation

protein O-linked glycosylation

protein mannosylation [inference]

protein O-linked mannosylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process

protein glycosylation

protein O-linked glycosylation

protein mannosylation [inference]

protein O-linked mannosylation

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

cellular process [inference]

ensheathment of neurons [inference]

axon ensheathment [inference]

myelination

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

localization of cell

cellular component organization or biogenesis [inference]

cellular component organization [inference]

extracellular structure organization [inference]

extracellular matrix organization [inference]

basement membrane organization

external encapsulating structure organization [inference]

extracellular matrix organization [inference]

basement membrane organization

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

sensory perception [inference]

sensory perception of mechanical stimulus [inference]

sensory perception of sound

developmental process [inference]

anatomical structure development [inference]

dentate gyrus development

animal organ development [inference]

brain development

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response [inference]

neuroinflammatory response [inference]

reactive gliosis

localization [inference]

localization of cell

Displaying **all 2** entries
GO Term	Evidence Code	PMID
membrane	ISO ISS
Golgi membrane	IBA IEA ISO ISS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle membrane [inference]

bounding membrane of organelle [inference]

Golgi membrane

Displaying **all 5** entries
GO Term	Evidence Code	PMID
manganese ion binding	IEA ISO ISS
alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity	IEA
carbohydrate binding	IEA
acetylglucosaminyltransferase activity	IEA ISO ISS
beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity	IBA IEA ISO

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

UDP-glycosyltransferase activity [inference]

acetylglucosaminyltransferase activity

hexosyltransferase activity [inference]

acetylglucosaminyltransferase activity

catalytic activity, acting on a protein [inference]

catalytic activity, acting on a glycoprotein [inference]

binding [inference]

carbohydrate binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

manganese ion binding

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K09666

Name

beta-1,2-N-acetylglucosaminyltransferase [EC:2.4.1.-]

References

11709191

Reactions

Displaying 1 entry
KEGG Reaction	Enzyme	Acceptor	Product
R07619	2.4.1.-	G61491DK	G85856KC

Disease

Disease Ontology

Displaying **all 8** entries
DO ID	Disease Name	Source
DOID:0050453	lissencephaly	Alliance of Genome Resources
DOID:0050560	Walker-Warburg syndrome	Alliance of Genome Resources
DOID:0050588	muscular dystrophy-dystroglycanopathy type B1	Alliance of Genome Resources
DOID:0110292	autosomal recessive limb-girdle muscular dystrophy type 2O	Alliance of Genome Resources
DOID:0111236	congenital muscular dystrophy-dystroglycanopathy type A3	Alliance of Genome Resources
DOID:0112378	muscular dystrophy-dystroglycanopathy type B3	Alliance of Genome Resources
DOID:10584	retinitis pigmentosa	Alliance of Genome Resources
DOID:9884	muscular dystrophy	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 81 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Callorhinchus milii	103182759		CALMI25672
Danio rerio	571876	ZFIN:ZDB-GENE-070112-991	DANRE37989
Astyanax mexicanus	103031352		ASTMX11543
Ictalurus punctatus	108272261		ICTPU02282
Electrophorus electricus	113570473		ELEEL08533
Salmo salar	106584015		SALSA85750
Salmo trutta	115192207		SALTR29006
Gadus morhua	115555450		GADMO08131
Oryzias latipes	101165468		ORYLA13372
Oreochromis niloticus	100693796		ORENI23922

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Supported by JST NBDC Grant Number JPMJND2204

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Last updated: August 19, 2024