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iron responsive element binding protein 2

Summary

Gene Symbol

IREB2

Organism

Homo sapiens (human)

External Links

NCBI Gene

3658

PubChem

3658

Alliance of Genome Resources

HGNC:6115

Annotation

Keyword

3D-structure
4Fe-4S
Alternative splicing
Cytoplasm
Disease variant
Neurodegeneration
RNA-binding
Reference proteome
Ubl conjugation

Proteins

Displaying 1 entry
UniProt	Protein Name
P48200	Iron regulatory protein 2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 12 in total

1

2

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GO Term	Evidence Code	PMID
mRNA stabilization	TAS	9924025
intracellular iron ion homeostasis	IMP TAS	30915432
establishment of localization in cell
intestinal absorption	IEA
protoporphyrinogen IX biosynthetic process	IEA

GO Hierarchy

biological process

immune system process [inference]

myeloid cell homeostasis [inference]

erythrocyte homeostasis

metabolic process [inference]

nitrogen compound metabolic process [inference]

citrate metabolic process

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

tetrapyrrole biosynthetic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

organonitrogen compound metabolic process [inference]

tetrapyrrole metabolic process [inference]

porphyrin-containing compound metabolic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

protoporphyrinogen IX metabolic process [inference]

protoporphyrinogen IX biosynthetic process

tetrapyrrole biosynthetic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

organonitrogen compound biosynthetic process [inference]

tetrapyrrole biosynthetic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

heterocycle biosynthetic process [inference]

tetrapyrrole biosynthetic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

aromatic compound biosynthetic process [inference]

tetrapyrrole biosynthetic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

tetrapyrrole biosynthetic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

organic substance biosynthetic process [inference]

organic cyclic compound biosynthetic process [inference]

tetrapyrrole biosynthetic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

organonitrogen compound biosynthetic process [inference]

tetrapyrrole biosynthetic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

tricarboxylic acid metabolic process [inference]

citrate metabolic process

cellular aromatic compound metabolic process [inference]

aromatic compound biosynthetic process [inference]

tetrapyrrole biosynthetic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

tetrapyrrole metabolic process [inference]

porphyrin-containing compound metabolic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

protoporphyrinogen IX metabolic process [inference]

protoporphyrinogen IX biosynthetic process

tetrapyrrole biosynthetic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

tetrapyrrole biosynthetic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

cellular biosynthetic process [inference]

heterocycle biosynthetic process [inference]

tetrapyrrole biosynthetic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

aromatic compound biosynthetic process [inference]

tetrapyrrole biosynthetic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

tetrapyrrole biosynthetic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

heterocycle metabolic process [inference]

heterocycle biosynthetic process [inference]

tetrapyrrole biosynthetic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

tetrapyrrole metabolic process [inference]

porphyrin-containing compound metabolic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

protoporphyrinogen IX metabolic process [inference]

protoporphyrinogen IX biosynthetic process

tetrapyrrole biosynthetic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

primary metabolic process [inference]

tricarboxylic acid cycle

small molecule metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

tricarboxylic acid metabolic process [inference]

citrate metabolic process

organic substance metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

tricarboxylic acid metabolic process [inference]

citrate metabolic process

organic cyclic compound metabolic process [inference]

tetrapyrrole metabolic process [inference]

porphyrin-containing compound metabolic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

protoporphyrinogen IX metabolic process [inference]

protoporphyrinogen IX biosynthetic process

tetrapyrrole biosynthetic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

organic cyclic compound biosynthetic process [inference]

tetrapyrrole biosynthetic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

organonitrogen compound metabolic process [inference]

tetrapyrrole metabolic process [inference]

porphyrin-containing compound metabolic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

protoporphyrinogen IX metabolic process [inference]

protoporphyrinogen IX biosynthetic process

tetrapyrrole biosynthetic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

organonitrogen compound biosynthetic process [inference]

tetrapyrrole biosynthetic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

organic substance biosynthetic process [inference]

organic cyclic compound biosynthetic process [inference]

tetrapyrrole biosynthetic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

organonitrogen compound biosynthetic process [inference]

tetrapyrrole biosynthetic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

tricarboxylic acid metabolic process [inference]

citrate metabolic process

cellular aromatic compound metabolic process [inference]

aromatic compound biosynthetic process [inference]

tetrapyrrole biosynthetic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

tetrapyrrole metabolic process [inference]

porphyrin-containing compound metabolic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

protoporphyrinogen IX metabolic process [inference]

protoporphyrinogen IX biosynthetic process

tetrapyrrole biosynthetic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

tetrapyrrole biosynthetic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

cellular biosynthetic process [inference]

heterocycle biosynthetic process [inference]

tetrapyrrole biosynthetic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

aromatic compound biosynthetic process [inference]

tetrapyrrole biosynthetic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

tetrapyrrole biosynthetic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

heterocycle metabolic process [inference]

heterocycle biosynthetic process [inference]

tetrapyrrole biosynthetic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

tetrapyrrole metabolic process [inference]

porphyrin-containing compound metabolic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

protoporphyrinogen IX metabolic process [inference]

protoporphyrinogen IX biosynthetic process

tetrapyrrole biosynthetic process [inference]

porphyrin-containing compound biosynthetic process [inference]

protoporphyrinogen IX biosynthetic process

cellular developmental process [inference]

cell differentiation [inference]

leukocyte differentiation [inference]

myeloid leukocyte differentiation [inference]

osteoclast differentiation

myeloid cell differentiation [inference]

myeloid leukocyte differentiation [inference]

osteoclast differentiation

multicellular organismal process [inference]

system process [inference]

digestive system process [inference]

intestinal absorption

post-embryonic development

multicellular organismal-level homeostasis [inference]

homeostasis of number of cells [inference]

myeloid cell homeostasis [inference]

erythrocyte homeostasis

multicellular organismal-level chemical homeostasis [inference]

multicellular organismal-level iron ion homeostasis

developmental process [inference]

cellular developmental process [inference]

cell differentiation [inference]

leukocyte differentiation [inference]

myeloid leukocyte differentiation [inference]

osteoclast differentiation

myeloid cell differentiation [inference]

myeloid leukocyte differentiation [inference]

osteoclast differentiation

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular iron ion homeostasis

multicellular organismal-level homeostasis [inference]

homeostasis of number of cells [inference]

myeloid cell homeostasis [inference]

erythrocyte homeostasis

multicellular organismal-level chemical homeostasis [inference]

multicellular organismal-level iron ion homeostasis

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular iron ion homeostasis

monoatomic cation homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular iron ion homeostasis

multicellular organismal-level iron ion homeostasis

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular iron ion homeostasis

inorganic ion homeostasis [inference]

multicellular organismal-level chemical homeostasis [inference]

multicellular organismal-level iron ion homeostasis

localization [inference]

establishment of localization [inference]

transport [inference]

intestinal absorption

establishment of localization in cell

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of translation

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

post-transcriptional regulation of gene expression [inference]

regulation of translation [inference]

negative regulation of translation

regulation of RNA stability [inference]

regulation of mRNA stability [inference]

mRNA stabilization

RNA stabilization [inference]

mRNA stabilization

positive regulation of gene expression [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of gene expression [inference]

negative regulation of translation

regulation of mRNA catabolic process [inference]

regulation of mRNA stability [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of translation

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of translation

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of translation

negative regulation of catabolic process [inference]

negative regulation of cellular catabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of translation

negative regulation of protein metabolic process [inference]

negative regulation of translation

negative regulation of RNA metabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of translation

negative regulation of cellular catabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of amide metabolic process [inference]

negative regulation of translation

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of protein metabolic process [inference]

negative regulation of translation

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

regulation of catabolic process [inference]

negative regulation of catabolic process [inference]

negative regulation of cellular catabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

regulation of cellular catabolic process [inference]

negative regulation of cellular catabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

regulation of RNA stability [inference]

regulation of mRNA stability [inference]

mRNA stabilization

RNA stabilization [inference]

mRNA stabilization

regulation of mRNA catabolic process [inference]

regulation of mRNA stability [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

regulation of RNA metabolic process [inference]

regulation of RNA stability [inference]

regulation of mRNA stability [inference]

mRNA stabilization

RNA stabilization [inference]

mRNA stabilization

negative regulation of RNA metabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

regulation of mRNA metabolic process [inference]

regulation of mRNA catabolic process [inference]

regulation of mRNA stability [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of translation

negative regulation of cellular catabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

post-transcriptional regulation of gene expression [inference]

regulation of translation [inference]

negative regulation of translation

regulation of RNA stability [inference]

regulation of mRNA stability [inference]

mRNA stabilization

RNA stabilization [inference]

mRNA stabilization

positive regulation of gene expression [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of gene expression [inference]

negative regulation of translation

regulation of mRNA catabolic process [inference]

regulation of mRNA stability [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of translation

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of translation

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

regulation of cellular catabolic process [inference]

negative regulation of cellular catabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

regulation of RNA stability [inference]

regulation of mRNA stability [inference]

mRNA stabilization

RNA stabilization [inference]

mRNA stabilization

regulation of mRNA catabolic process [inference]

regulation of mRNA stability [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

regulation of RNA metabolic process [inference]

regulation of RNA stability [inference]

regulation of mRNA stability [inference]

mRNA stabilization

RNA stabilization [inference]

mRNA stabilization

negative regulation of RNA metabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

regulation of mRNA metabolic process [inference]

regulation of mRNA catabolic process [inference]

regulation of mRNA stability [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

regulation of amide metabolic process [inference]

regulation of translation [inference]

negative regulation of translation

negative regulation of amide metabolic process [inference]

negative regulation of translation

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of amide metabolic process [inference]

negative regulation of translation

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of protein metabolic process [inference]

negative regulation of translation

regulation of protein metabolic process [inference]

regulation of translation [inference]

negative regulation of translation

negative regulation of protein metabolic process [inference]

negative regulation of translation

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

post-transcriptional regulation of gene expression [inference]

regulation of translation [inference]

negative regulation of translation

regulation of RNA stability [inference]

regulation of mRNA stability [inference]

mRNA stabilization

RNA stabilization [inference]

mRNA stabilization

positive regulation of gene expression [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of gene expression [inference]

negative regulation of translation

regulation of mRNA catabolic process [inference]

regulation of mRNA stability [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of translation

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of translation

negative regulation of protein metabolic process [inference]

negative regulation of translation

negative regulation of RNA metabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

regulation of protein metabolic process [inference]

regulation of translation [inference]

negative regulation of translation

negative regulation of protein metabolic process [inference]

negative regulation of translation

regulation of RNA metabolic process [inference]

regulation of RNA stability [inference]

regulation of mRNA stability [inference]

mRNA stabilization

RNA stabilization [inference]

mRNA stabilization

negative regulation of RNA metabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

regulation of mRNA metabolic process [inference]

regulation of mRNA catabolic process [inference]

regulation of mRNA stability [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

regulation of RNA metabolic process [inference]

regulation of RNA stability [inference]

regulation of mRNA stability [inference]

mRNA stabilization

RNA stabilization [inference]

mRNA stabilization

negative regulation of RNA metabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

regulation of mRNA metabolic process [inference]

regulation of mRNA catabolic process [inference]

regulation of mRNA stability [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

regulation of protein metabolic process [inference]

regulation of translation [inference]

negative regulation of translation

negative regulation of protein metabolic process [inference]

negative regulation of translation

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of translation

negative regulation of catabolic process [inference]

negative regulation of cellular catabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of translation

negative regulation of protein metabolic process [inference]

negative regulation of translation

negative regulation of RNA metabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of translation

negative regulation of cellular catabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of amide metabolic process [inference]

negative regulation of translation

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of protein metabolic process [inference]

negative regulation of translation

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of translation

negative regulation of cellular catabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

regulation of RNA metabolic process [inference]

regulation of RNA stability [inference]

regulation of mRNA stability [inference]

mRNA stabilization

RNA stabilization [inference]

mRNA stabilization

negative regulation of RNA metabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

regulation of mRNA metabolic process [inference]

regulation of mRNA catabolic process [inference]

regulation of mRNA stability [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of translation

negative regulation of cellular catabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

post-transcriptional regulation of gene expression [inference]

regulation of translation [inference]

negative regulation of translation

regulation of RNA stability [inference]

regulation of mRNA stability [inference]

mRNA stabilization

RNA stabilization [inference]

mRNA stabilization

positive regulation of gene expression [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of gene expression [inference]

negative regulation of translation

regulation of mRNA catabolic process [inference]

regulation of mRNA stability [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of translation

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of translation

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

regulation of cellular catabolic process [inference]

negative regulation of cellular catabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

regulation of RNA stability [inference]

regulation of mRNA stability [inference]

mRNA stabilization

RNA stabilization [inference]

mRNA stabilization

regulation of mRNA catabolic process [inference]

regulation of mRNA stability [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of translation

negative regulation of cellular catabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

regulation of biological quality [inference]

regulation of RNA stability [inference]

regulation of mRNA stability [inference]

mRNA stabilization

RNA stabilization [inference]

mRNA stabilization

Displaying **all 3** entries
GO Term	Evidence Code	PMID
mitochondrion	IBA
cytosol	IBA TAS
cytoplasm	NAS	7983023

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
protein binding	IPI	19762596 19762597 23891004
iron-responsive element binding	IBA IMP TAS	23891004 9924025
aconitate hydratase activity	IBA
metal ion binding	IEA
4 iron, 4 sulfur cluster binding	IBA

GO Hierarchy

molecular function

catalytic activity [inference]

lyase activity [inference]

carbon-oxygen lyase activity [inference]

hydro-lyase activity [inference]

aconitate hydratase activity

binding [inference]

protein binding

ion binding [inference]

cation binding [inference]

metal ion binding

metal cluster binding [inference]

iron-sulfur cluster binding [inference]

4 iron, 4 sulfur cluster binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

RNA binding

mRNA binding [inference]

iron-responsive element binding

translation regulator activity, nucleic acid binding [inference]

mRNA regulatory element binding translation repressor activity

translation regulator activity [inference]

translation repressor activity [inference]

mRNA regulatory element binding translation repressor activity

translation regulator activity, nucleic acid binding [inference]

mRNA regulatory element binding translation repressor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

3-isopropylmalate dehydratase

Functional Category

C: Energy production and conversion
E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones

Displaying **all 7** entries
Gene Ontology
3-isopropylmalate dehydratase activity
4 iron, 4 sulfur cluster binding
amino acid biosynthetic process
iron-sulfur cluster binding
leucine biosynthetic process
lyase activity
metal ion binding

Displaying **all 6** entries
InterPro
Aconitase A/isopropylmalate dehydratase small subunit, swivel domain
Aconitase family, 4Fe-4S cluster binding site
Aconitase, iron-sulfur domain
Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain
Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3
Aconitase/3-isopropylmalate dehydratase, swivel

Disease

Disease Ontology

Displaying **all 5** entries
DO ID	Disease Name	Source
DOID:10652	Alzheimer's disease	Alliance of Genome Resources
DOID:11758	iron deficiency anemia	Alliance of Genome Resources
DOID:13268	porphyria	Alliance of Genome Resources
DOID:2018	hyperinsulinism	Alliance of Genome Resources
DOID:2355	anemia	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 92 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	41269		FB:FBgn0024957
Drosophila melanogaster	42689		FB:FBgn0024958
Mus musculus	64602		MGI:1928268	MOUSE61197
Rattus norvegicus	64831		RGD:621539	RATNO41513
Xenopus laevis	414584		Xenbase:XB-GENE-943202
Pan troglodytes	467731	9598_0:003d1b		PANTR10915
Canis lupus familiaris	475134			CANLF03347
Bos taurus	539404			BOVIN16578
Danio rerio	652982		ZFIN:ZDB-GENE-051205-1	DANRE27569
Macaca mulatta	710239			MACMU42867

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements