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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
integrin subunit alpha 7
Summary
- Gene Symbol
-
- ITGA7
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- ADP-ribosylation
- Alternative splicing
- Calcium
- Cell adhesion
- Cell shape
- Cleavage on pair of basic residues
- Congenital muscular dystrophy
- Direct protein sequencing
- Disulfide bond
- Glycoprotein
- Integrin
- Metal-binding
- Receptor
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| regulation of cell shape | ||
| heterotypic cell-cell adhesion | ||
| integrin-mediated signaling pathway | ||
| muscle organ development |
| GO Term | Evidence Code | PMID |
|---|---|---|
| external side of plasma membrane | ||
| plasma membrane | ||
| integrin complex | ||
| cell surface |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| integrin binding | ||
| metal ion binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- integrin
- Functional Category
-
- E: Amino acid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- Q: Secondary metabolites biosynthesis, transport and catabolism
| Gene Ontology |
|---|
| cell adhesion mediated by integrin |
| cell-matrix adhesion |
| integrin binding |
| integrin-mediated signaling pathway |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050700 | cardiomyopathy | |
| DOID:0080000 | muscular disease | |
| DOID:0110639 | congenital muscular dystrophy due to integrin alpha-7 deficiency | |
| DOID:11723 | Duchenne muscular dystrophy | |
| DOID:162 | cancer | |
| DOID:1826 | epilepsy | |
| DOID:2349 | arteriosclerosis |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 16404 | MGI:102700 | MOUSE01674 | ||
| 32275 | FB:FBgn0004456 | |||
| 81008 | RGD:71022 | RATNO39097 | ||
| 176296 | WB:WBGene00002081 | |||
| 451967 | 9598_0:00352a | PANTR05644 | ||
| 481097 | CANLF01275 | |||
| 506953 | BOVIN29675 | |||
| 707279 | MACMU03983 | |||
| 100006255 | ZFIN:ZDB-GENE-070501-10 | |||
| 100087799 | ORNAN01580 |
