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Integrin alpha-7

Summary

UniProt ID

Q13683

Gene Symbol

ITGA7
UNQ406/PRO768

Gene ID

3679

Organism

Homo sapiens (human)

External Links

GlyGen: Q13683
PubChem: Q13683
Re-Glyco: Q13683

Annotation

Keyword

ADP-ribosylation
Alternative splicing
Calcium
Cell adhesion
Cell shape
Cleavage on pair of basic residues
Congenital muscular dystrophy
Direct protein sequencing
Disulfide bond
Glycoprotein
Integrin
Metal-binding
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix

Gene Ontology (GO)

Displaying **all 4** entries
GO Term
plasma membrane
external side of plasma membrane
cell surface
integrin complex

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying **all 9** entries
GO Term
cell-matrix adhesion
integrin-mediated signaling pathway
regulation of cell shape
heterotypic cell-cell adhesion
endodermal cell differentiation
leukocyte migration
cell-cell adhesion
muscle organ development
cell adhesion mediated by integrin

Displaying **all 2** entries
GO Term
metal ion binding
integrin binding

Annotation information from UniProt.

Sequence

MAGARSRDPWGASGICYLFGSLLVELLFSRAVAFNLDVMGALRKEGEPGSLFGFSVALHRQLQPRPQSWLLVGAPQALALPGQQANRTGGLFACPLSLEETDCYRVDIDQGADMQKESKENQWLGVSVRSQGPGGKIVTCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGEWKFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSADLAHLDDGPYEAGGEKEQDPRLIPVPANSYFGLLFVTNIDSSDPDQLVYKTLDPADRLPGPAGDLALNSYLGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVMLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQGGHWAGISPLRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSLGVVAKPSQVLEGEAVGIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSIDLEQPNCAGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALDPAEKPLCLSNENASHVECELGNPMKRGAQVTFYLILSTSGISIETTELEVELLLATISEQELHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNITLDCARGTANCVVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNLMLRDASTVIPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAKHPEATVPQYHAVKIPREDRQQFKEEKTGTILRNNWGSPRREGPDAHPILAADGHPELGPDGHPGPGTA

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 5** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
86	N-linked (GlcNAc...) asparagine			UniProt GlyGen
786	N-linked (GlcNAc...) asparagine		G80920RR	UniProt GlyGen
989	N-linked (GlcNAc...) asparagine		G01650EU G28541PG G31852PQ G41247ZX	UniProt GlyGen
1025	N-linked (GlcNAc...) asparagine	19159218	G46503DX G80920RR G62765YT	UniProt GlyGen
1045	N-linked (GlcNAc...) asparagine		G00912UN G80920RR G62765YT G31852PQ G41247ZX	UniProt GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 3** entries
Pathway Name	Organism
ECM proteoglycans	Homo sapiens
Integrin cell surface interactions	Homo sapiens
Laminin interactions	Homo sapiens

Disease

Displaying **all 3** entries
DO ID	Disease Name	Source
DOID:0080000	muscular disease	Alliance of Genome Resources
DOID:0110639	congenital muscular dystrophy due to integrin alpha-7 deficiency	Alliance of Genome Resources
DOID:11723	Duchenne muscular dystrophy	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

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Guidelines

Summary

External Links

Annotation

International Collaboration

Acknowledgements