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Integrin cell surface interactions

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
Mg2+Collagen type I:Mg2+:Integrin alpha 11 beta 1Collagen type I fibrilIntegrin alpha11beta1Collagen type II fibrilIntegrin alpha10beta1:Collagen type II fibril:Mg2+Integrin alpha10beta1Collagen type VII fibrilCollagen type VII fibril:Integrin alpha2beta1ITGA2:ITGB1ITGA1:ITGB1Collagen type XIII:Integrin alpha1beta1Collagen type XIIICollagen type VI network, Collagen type IXCollagen tupe VI network, Collagen type IX:Integrin alpha10beta1Collagen type X:Integrin alpha11beta1Collagen type IXIntegrins alphaVbeta3, alphaVbeta5, alpha3beta1, alpha5beta1Endostatin:Integrins alphaVbeta3, alphaVbeta5, alpha3beta1, alpha5beta1EndostatinCanstatinCanstatin:Integrins alphaVbeta3, alphaVbeta5Integrins alphaVbeta3, alphaVbeta5Integrin alpha3beta1, alpha4beta1Integrin alpha3beta1, alpha4beta1:THBS1 trimerTHBS1 trimerSPP1Integrin alpha8beta1:SPP1Integrin alpha8beta1CD44SPP1:CD44JAM2:JAM3integrin alpha4beta1:JAM2:JAM3VLA-4MADCAM1-1Integrin alpha4beta7:MADCAM1Integrin alpha4beta7VCAM1Integrin alpha9beta1:VCAM-1Integrin alpha9beta1Integrin alphaDbeta2Integrin alphaDbeta2:fibrin multimer:Mg++fibrin multimerVTNVTN:Integrin alphaVbeta3, 5, 8Integrin alphaVbeta3, 5, 8ICAM 1-5LFA-1:ICAM 1-5Integrin alphaLbeta2JAM3Integrin alphaMbeta2:JAM3Integrin MAC-1IBSPIntegrin alphaVbeta3:IBSPIntegrin alphaVbeta3Integrin alphaVbeta3:Fibrillin-1FBN1PECAM1Integrin alphaVbeta3:PECAM1Integrin alpha2bbeta3Integrin alpha2bbeta3:FN1(32-2386)FNIntegrin alphaIIbbeta3:VWF multimerVWF multimerLUMLUM:Integrin alpha2beta1Integrin alpha5beta1, Integrin alphaVbeta3, CD47COMP pentamer:Integrin alpha5beta1, Integrin alphaVbeta3, CD47COMP pentamerHSPG2(3687-4391):Integrin alpha2beta1EndorepellinCollagen types III, IV, V, VI, VIII, IX, XVICollagen types III, IV, V, VI, VIII, IX, XVI:Integrins alpha1beta 1, alpha2beta1Integrin alpha1beta1, alpha2beta1, alpha10beta1Integrins alpha1beta1, alpha2beta1:Collagen type I fibril:Mg2+Collagen type II fibril:Integrins alpha2beta1, alpha1beta1, alpha11beta1Integrins alpha1beta1, alpha2beta1, alpha11beta1Integrins alpha1beta1, alpha2beta1:Collagen type IV networks:Mg2+Collagen IVCollagen type X networkCollagen type X network:Integrin alpha2beta1Collagen type XXIII:Integrin alpha2beta1Collagen type XXIIICollagen type IV networks:Integrin alpha10beta1ArrestenArresten:Integrin alpha1beta1Integrins alphaVbeta3, alpha3beta1Tumstatin:Integrins alphaVbeta3, alpha3beta1TumstatinTetrastatin:Integrin alphaVbeta3Collagen alpha-4(IV) NC1 domainsFibronectin matrixIntegrin alpha4beta1, alpha8beta1, alphaVbeta6:Fibronectin matrixIntegrin alpha4beta1, alpha8beta1, alphaVbeta1, alphaVbeta3, alphaVbeta6SPP1:Integrin alpha5beta1, alpha9beta1Integrin alpha5beta1, alpha9beta1SPP1:Integrin alpha4beta1SPP1:Integrin alphaVBeta1,3,5Integrin alphaVBeta1,3,5integrin alpha4beta1:VCAM1AN100226ITGA4:ITGB1:natalizumabTenascin-C hexamerIntegrin alpha8beta1:Tenascin-C hexamerIntegrin alpha9beta1:Tenascin-C hexamerIntegrin alphaXbeta2Integrin alphaXbeta2:fibrin multimerIntegrin alphaXbeta2:JAM3F11RIntegrin alphaLbeta2:F11RBSGBSG:Integrin alpha3beta1, alpha6beta1Integrin alpha3beta1, alpha6beta1TNCIntegrin alphaVbeta3:TenascinIntegrin alphaVbeta3:VWF multimerIntegrin alphaEbeta7Integrin alphaEbeta7:Cadherin-1CDH1Integrin alpha IIb beta 3:Fibrin complexIntegrin alphaIIbbeta3:THBS1TSP1Integrins alphaVbeta1 (other beta 1)Agrin:Integrin alphaVbeta1 (other beta1)AGRNKDRHSPG2(3687-4391):KDR
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018
Displaying entries 1 - 10 of 64 in total
UniProt ID Protein Name Gene Symbol Pathway Viewer
O00468 Agrin
  • AGRIN
  • AGRN
 view
O75578 Integrin alpha-10
  • ITGA10
 view
P02462 Collagen alpha-1(IV) chain
  • COL4A1
 view
P02671 Fibrinogen alpha chain
  • FGA
 view
P02675 Fibrinogen beta chain
  • FGB
 view
P02679 Fibrinogen gamma chain
  • FGG
 view
P02751 Fibronectin
  • FN
  • FN1
 view
P04004 Vitronectin
  • VTN
 view
P05106 Integrin beta-3
  • GP3A
  • ITGB3
 view
P05107 Integrin beta-2
  • CD18
  • ITGB2
  • MFI7
 view
Displaying all 5 entries
GlyCosmos Lectin UniProt ID Lectin Name Pathway Viewer
GL_001410 P20849 Collagen alpha-1(IX) chain view
GL_002323 P05362 Intercellular adhesion molecule 1 view
GL_002356 P24821 Tenascin view
GL_002853 P04004 Vitronectin view
GL_004606 P35613 Basigin view
If you want to check the location of a particular molecule, you can do so by clicking on the "Switching Highlight" button on the page you have navigated to by clicking on "view".
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025