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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Dopamine transporter
Summary
- Gene Symbol
-
- DAT
- Organism
- Drosophila melanogaster (fruit fly)
Annotation
- Keyword
-
- 3D-structure
- Cell membrane
- Disulfide bond
- Glycoprotein
- Metal-binding
- Neurotransmitter transport
- Reference proteome
- Sodium
- Symport
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| A0A0B4KEX2 |
|
| Q7K4Y6 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| norepinephrine transport | ||
| dopamine uptake involved in synaptic transmission | ||
| amino acid transport | ||
| sleep | ||
| sodium ion transmembrane transport |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| membrane | ||
| neuronal cell body membrane | ||
| plasma membrane | ||
| presynaptic membrane | ||
| axon |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| metal ion binding |
|
|
| cocaine binding | ||
| dopamine:sodium symporter activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Transporter
- Functional Category
-
- E: Amino acid transport and metabolism
- K: Transcription
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| symporter activity |
Alliance of Genome Resources
- Expression
| Location | References |
|---|---|
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050741 | alcohol dependence | |
| DOID:0050742 | nicotine dependence | |
| DOID:0060041 | autism spectrum disorder | |
| DOID:0070489 | classic dopamine transporter deficiency syndrome | |
| DOID:0080832 | mild cognitive impairment | |
| DOID:0080855 | Parkinsonism | |
| DOID:0090145 | dopamine beta-hydroxylase deficiency | |
| DOID:10273 | heart conduction disease | |
| DOID:10763 | hypertension | |
| DOID:1094 | attention deficit hyperactivity disorder |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 6494123 | 7217_0:002848 | |||
| 6531391 | 7245_1:001353 | |||
| 6548430 | 7220_1:0022b4 | |||
| 6571527 | 7222_1:000635 | |||
| 6579673 | 7230_0:001e3c | |||
| 6590142 | 7234_1:000d52 | |||
| 6609460 | 7238_1:001336 | |||
| 6624853 | 7244_1:001c57 | |||
| 6640614 | 7260_0:000893 | |||
| 6734787 | 7240_0:002483 |
