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Imaginal disc growth factor 6

Summary

Gene Symbol

Idgf6

Organism

Drosophila melanogaster (fruit fly)

External Links

NCBI Gene

36868

PubChem

36868

Alliance of Genome Resources

FB:FBgn0013763

Annotation

Keyword

Chitin-binding
Developmental protein
Direct protein sequencing
Disulfide bond
Glycoprotein
Reference proteome
Secreted
Signal

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q23997
A0A0B4LFJ1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
wound healing	IMP	26838602
regulation of chitin metabolic process	IMP	32770153
regulation of tube architecture, open tracheal system	IMP	32770153
chitin catabolic process	IBA
chitin-based cuticle development	IMP	26838602 32770153

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan catabolic process [inference]

chitin catabolic process

chitin metabolic process [inference]

chitin catabolic process

organonitrogen compound catabolic process [inference]

aminoglycan catabolic process [inference]

chitin catabolic process

catabolic process [inference]

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

aminoglycan catabolic process [inference]

chitin catabolic process

carbohydrate derivative catabolic process [inference]

aminoglycan catabolic process [inference]

chitin catabolic process

amino sugar catabolic process [inference]

glucosamine-containing compound catabolic process [inference]

chitin catabolic process

organonitrogen compound catabolic process [inference]

aminoglycan catabolic process [inference]

chitin catabolic process

primary metabolic process [inference]

carbohydrate metabolic process

organic substance metabolic process [inference]

carbohydrate metabolic process

macromolecule metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan catabolic process [inference]

chitin catabolic process

chitin metabolic process [inference]

chitin catabolic process

macromolecule catabolic process [inference]

aminoglycan catabolic process [inference]

chitin catabolic process

carbohydrate derivative metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan catabolic process [inference]

chitin catabolic process

chitin metabolic process [inference]

chitin catabolic process

amino sugar metabolic process [inference]

amino sugar catabolic process [inference]

glucosamine-containing compound catabolic process [inference]

chitin catabolic process

glucosamine-containing compound metabolic process [inference]

chitin metabolic process [inference]

chitin catabolic process

glucosamine-containing compound catabolic process [inference]

chitin catabolic process

carbohydrate derivative catabolic process [inference]

aminoglycan catabolic process [inference]

chitin catabolic process

amino sugar catabolic process [inference]

glucosamine-containing compound catabolic process [inference]

chitin catabolic process

organonitrogen compound metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan catabolic process [inference]

chitin catabolic process

chitin metabolic process [inference]

chitin catabolic process

organonitrogen compound catabolic process [inference]

aminoglycan catabolic process [inference]

chitin catabolic process

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

aminoglycan catabolic process [inference]

chitin catabolic process

carbohydrate derivative catabolic process [inference]

aminoglycan catabolic process [inference]

chitin catabolic process

amino sugar catabolic process [inference]

glucosamine-containing compound catabolic process [inference]

chitin catabolic process

organonitrogen compound catabolic process [inference]

aminoglycan catabolic process [inference]

chitin catabolic process

multicellular organismal process [inference]

molting cycle process [inference]

ecdysis, chitin-based cuticle

developmental process [inference]

anatomical structure development [inference]

cuticle development [inference]

chitin-based cuticle development

animal organ development [inference]

imaginal disc development

response to stimulus [inference]

response to stress [inference]

response to wounding [inference]

wound healing

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of nitrogen compound metabolic process [inference]

regulation of chitin metabolic process

regulation of macromolecule metabolic process [inference]

regulation of polysaccharide metabolic process [inference]

regulation of chitin metabolic process

regulation of primary metabolic process [inference]

regulation of carbohydrate metabolic process [inference]

regulation of polysaccharide metabolic process [inference]

regulation of chitin metabolic process

regulation of biological quality [inference]

regulation of tube architecture, open tracheal system

Displaying **all 2** entries
GO Term	Evidence Code	PMID
extracellular region	HDA IBA	15466469
extracellular space	IDA	18342251

GO Hierarchy

cellular component

cellular anatomical entity [inference]

Displaying **all 3** entries
GO Term	Evidence Code	PMID
chitinase activity	IDA IKR IMR	18342251 7875581
chitin binding	IDA IEA	18342251
imaginal disc growth factor receptor binding	ISS

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on glycosyl bonds [inference]

hydrolase activity, hydrolyzing O-glycosyl compounds [inference]

chitinase activity

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

growth factor receptor binding [inference]

imaginal disc growth factor receptor binding

carbohydrate derivative binding [inference]

chitin binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Chitinase A

Functional Category

G: Carbohydrate transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying **all 5** entries
Gene Ontology
chitin binding
chitin catabolic process
chitinase activity
hydrolase activity, acting on glycosyl bonds
hydrolase activity

Displaying **all 5** entries
InterPro
Chitinase II
Chitinase insertion domain superfamily
Glycoside hydrolase family 18, catalytic domain
Glycoside hydrolase superfamily
Glycosyl hydrolases family 18 (GH18) active site

Alliance of Genome Resources

Expression

Displaying **all 4** entries
Location	References
cytoplasm	FB:FBrf0219073
membrane	FB:FBrf0231198
extracellular region	PMID:15466469
extracellular space	PMID:18342251

Disease

Disease Ontology

Displaying entries **11 - 20** of 30 in total

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DO ID	Disease Name	Source
DOID:1909	melanoma	Alliance of Genome Resources
DOID:2349	arteriosclerosis	Alliance of Genome Resources
DOID:2394	ovarian cancer	Alliance of Genome Resources
DOID:2841	asthma	Alliance of Genome Resources
DOID:3068	glioblastoma	Alliance of Genome Resources
DOID:3083	chronic obstructive pulmonary disease	Alliance of Genome Resources
DOID:3371	chondrosarcoma	Alliance of Genome Resources
DOID:3393	coronary artery disease	Alliance of Genome Resources
DOID:3770	pulmonary fibrosis	Alliance of Genome Resources
DOID:3908	lung non-small cell carcinoma	Alliance of Genome Resources

Ortholog

Displaying entries **31 - 40** of 54 in total

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Species	Gene ID	OrthoDB
Drosophila rhopaloa	108051241	1041015_1:0005ac
Drosophila takahashii	108054645	29030_0:00132a
Drosophila kikkawai	108076345	30033_1:003506
Drosophila ficusphila	108090378	30025_1:00212f
Drosophila eugracilis	108112555	29029_1:003443
Drosophila bipectinata	108133077	42026_0:0011b5
Drosophila elegans	108144350	30023_1:000a79
Drosophila miranda	108159613	7229_0:003223
Drosophila busckii	108596771	30019_1:000aae
Drosophila navojoa	108653651	7232_1:000e2f

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Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements